Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Tong-Xin Xie"'
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19412 (2011)
Squamous cell carcinoma of the head and neck (SCCHN) is the seventh most common cancer worldwide. Unfortunately, the survival of patients with SCCHN has not improved in the last 40 years, and thus new targets for therapy are needed. Recently, elevati
Externí odkaz:
https://doaj.org/article/3beda1567b1042a089b9622c4ad8b7a0
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
Supplementary Figures PDF - file 648K, This file contains supplementary figures S1-S5. Figure S1 has additional copy number analysis. Figure S2 expands on the integration of gene expression and copy number analysis. Figures S3-S4 provide additional d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15405d8619b8a7073c811fb586348df3
https://doi.org/10.1158/2159-8290.22530170.v1
https://doi.org/10.1158/2159-8290.22530170.v1
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
Supplementary Tables -XLSX file 2328K, This file contains supplemental tables S1-S14. These tables describe the clinical, pathological and genomic information for this study. Also included are GISTIC peak information, expression and copy number corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea24a3d1cce25ad579996d2700b9847
https://doi.org/10.1158/2159-8290.22530167
https://doi.org/10.1158/2159-8290.22530167
Autor:
Mitchell J. Frederick, Jeffrey N. Myers, David A. Wheeler, Richard A. Gibbs, Donna M. Muzny, Jing Wang, John N. Weinstein, Adel K. El-Naggar, Xifeng Wu, Patrick A. Zweidler-McKay, Jean-Pierre J. Issa, Woonbok Chung, Di Zhang, Tong-xin Xie, Elsa Cortez, Jennifer Drummond, Kyle Chang, Marcus V. Ortega Alves, Mei Zhao, David M. Neskey, Shhyam Moorthy, Linnea Bengtsson, Suk Young Yoo, Jiexin Zhang, Curtis R. Pickering
The survival of patients with oral squamous cell carcinoma (OSCC) has not changed significantly in several decades, leading clinicians and investigators to search for promising molecular targets. To this end, we conducted comprehensive genomic analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0124def50b57b5023ab4f2e11dc99bd
https://doi.org/10.1158/2159-8290.c.6546119.v1
https://doi.org/10.1158/2159-8290.c.6546119.v1
Autor:
Abdullah A. Osman, Jeffrey N. Myers, Faye M. Johnson, Heath D. Skinner, Ge Zhou, Carlos Caulin, Natalie L. Silver, Tong-xin Xie, Alison L. Fitzgerald, Mei Zhao, Nene N. Kalu, Mitchell J. Frederick, Jiping Wang, Ameeta A. Patel, Noriaki Tanaka
Supplementary Figure S5. Downregulation of MCl-1, XIAP and their cleavage by AZD-1775 in HPV+ HNSCC cells are caspase-dependent;and Supplementary Figure S6. mRNA levels of MCl-1, XIAP and stable forced expression of MCl-1 in HPV+ HNSCC cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a69d962e745906baaac347638efead
https://doi.org/10.1158/1078-0432.22458053
https://doi.org/10.1158/1078-0432.22458053
Autor:
Abdullah A. Osman, Jeffrey N. Myers, Faye M. Johnson, Heath D. Skinner, Ge Zhou, Carlos Caulin, Natalie L. Silver, Tong-xin Xie, Alison L. Fitzgerald, Mei Zhao, Nene N. Kalu, Mitchell J. Frederick, Jiping Wang, Ameeta A. Patel, Noriaki Tanaka
AZD-1775 as a single agent shows antitumor activity in HPV+ patient derived xenografts xenograft (PDX).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b39f369ce7ab2c4ac1846d1c388c8cc
https://doi.org/10.1158/1078-0432.22458050.v1
https://doi.org/10.1158/1078-0432.22458050.v1
Autor:
Ehab Y. Hanna, Jeffrey N. Myers, Alexander Gelbard, Mitchell J. Frederick, Mei Zhao, Ning-Wei Li, Tong-Xin Xie, June Goo Lee, Tilahun Jiffar, Diana Bell, Michael E. Kupferman, Yoko Takahashi
PDF file - 90K, Expression pattern of epithelial-mesenchymal transition markers in early and late passage SNUC cells. Expression pattern of epithelial markers (pan-keratin and E-cadherin) and mesenchymal markers (α-SMA and vimentin) in both early (a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49bed49541b4909e2879dca8bfe44e1e
https://doi.org/10.1158/1078-0432.22447139
https://doi.org/10.1158/1078-0432.22447139
Autor:
Ehab Y. Hanna, Jeffrey N. Myers, Alexander Gelbard, Mitchell J. Frederick, Mei Zhao, Ning-Wei Li, Tong-Xin Xie, June Goo Lee, Tilahun Jiffar, Diana Bell, Michael E. Kupferman, Yoko Takahashi
PDF file - 88K, STR profile of the original specimen and MDA8788 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399823103c8bbe41c62f076e1622c0e6
https://doi.org/10.1158/1078-0432.22447127.v1
https://doi.org/10.1158/1078-0432.22447127.v1
Autor:
Jeffrey N. Myers, Carlos Caulin, Richard A. Gibbs, David A. Wheeler, Vlad C. Sandulache, Ge Zhou, Curtis R. Pickering, Mei Zhao, Thomas J. Ow, Tong-Xin Xie, Daisuke Sano
PDF file - 1MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a6cb8ba04726f9c02b90a4199f4039
https://doi.org/10.1158/1078-0432.22443209.v1
https://doi.org/10.1158/1078-0432.22443209.v1
Autor:
Ehab Y. Hanna, Jeffrey N. Myers, Alexander Gelbard, Mitchell J. Frederick, Mei Zhao, Ning-Wei Li, Tong-Xin Xie, June Goo Lee, Tilahun Jiffar, Diana Bell, Michael E. Kupferman, Yoko Takahashi
PDF file - 104K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092c1e9cb96def30a8e0f9215eb82aab
https://doi.org/10.1158/1078-0432.22447130.v1
https://doi.org/10.1158/1078-0432.22447130.v1