Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Tong-Fei Li"'
Autor:
Zhijie Xu, Zhiyang Zhou, Xiaoxin Yang, Abhimanyu Thakur, Ning Han, Hai-Tao Li, Liu-Gen Li, Jun Hu, Tong-fei Li, Yuanliang Yan
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Pazopanib (PAZ), an oral multi-tyrosine kinase inhibitor, demonstrates promising cytostatic activities against various human cancers. However, its clinical utility is limited by substantial side effects and therapeutic resistance. We develop
Externí odkaz:
https://doaj.org/article/f5e4605a3ed24f9abc97e48608e701f5
Autor:
Chuan-Yong Xiao, Yijun Tang, Tao Ren, Cunqing Kong, Hui You, Xiao-Feng Bai, Qi Huang, Yi Chen, Liu-Gen Li, Mei-Yi Liu, Fan Leng, Ning Han, Tong-Fei Li, Mei-Fang Wang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 286, Iss , Pp 117161- (2024)
Macrophage polarization facilitates the inflammatory response and intensified fibrosis in the silicosis microenvironment by a mechanism related to macrophage pyroptosis, although the upstream target remains poorly defined. Currently, there are few re
Externí odkaz:
https://doaj.org/article/22fdeb12b3ed4582b3d0ecaec3c74bec
Autor:
Liu-Gen Li, Xing-Chun Peng, Zi-Yi Yang, Ning Han, Chang-Long Gou, Jun Shi, Li-Li Yu, Nan-Nan Chen, Ting-Ting Yu, Tong-Fei Li, Xian-Yu Li, Jun Hu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Chemotherapeutic agents can inhibit the proliferation of malignant cells due to their cytotoxicity, which is limited by collateral damage. Dihydroartemisinin (DHA), has a selective anti-cancer effect, whose target and mechanism remain uncove
Externí odkaz:
https://doaj.org/article/cef8aa1158df444b860bcc60c3b7c2b1
Autor:
Yuan-Jian Hui, Ting-Ting Yu, Liu-Gen Li, Xing-Chun Peng, Mao-Jun Di, Hui Liu, Wen-Long Gu, Tong-Fei Li, Kai-Liang Zhao, Wei-Xing Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract B-Myb has received considerable attention for its critical tumorigenic function of supporting DNA repair. However, its modulatory effects on chemotherapy and immunotherapy have rarely been reported in colorectal cancer. Bortezomib (BTZ) is a
Externí odkaz:
https://doaj.org/article/fb4acb4c47c04685a12e6ec1253507d2
Autor:
Tong-fei Li, Zhijie Xu, Kui Zhang, Xiaoxin Yang, Abhimanyu Thakur, Shuangshuang Zeng, Yuanliang Yan, Wangrui Liu, Ming Gao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 277, Iss , Pp 116372- (2024)
Environmental pollution, including air pollution, plastic contamination, and heavy metal exposure, is a pressing global issue. This crisis contributes significantly to pollution-related diseases and is a critical risk factor for chronic health condit
Externí odkaz:
https://doaj.org/article/a1e60601160b4a6192bd383ade5a8850
Autor:
Yuanliang Yan, Xiaoxin Yang, Ning Han, Yuanhong Liu, Qiuju Liang, Liu-Gen Li, Jun Hu, Tong-Fei Li, Zhijie Xu
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Dihydroartemisinin (DHA), a natural product derived from the herbal medicine Artemisia annua, is recently used as a novel anti-cancer agent. However, some intrinsic disadvantages limit its potential for clinical management of cancer patients
Externí odkaz:
https://doaj.org/article/e62d633dbab848b88b884c7f3f7828cf
Autor:
Qi-Rui Li, Hua-Zhen Xu, Rong-Cheng Xiao, Bin Liu, Tian-Qi Ma, Ting-Ting Yu, Liu-Gen Li, Mei-Fang Wang, Li Zhao, Xiao Chen, Tong-Fei Li
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
In our previous study, target drug delivery and treatment of malignant tumors have been achieved by using platelets as carriers loading nano-chemotherapeutic agents (ND-DOX). However, drug release from ND-DOX-loaded platelets is dependent on negative
Externí odkaz:
https://doaj.org/article/0e9492a586f141caa48f48de9acef6de
Autor:
Qi-Rui Li, Hua-Zhen Xu, Rong-Cheng Xiao, Yan Liu, Jun-Ming Tang, Jian Li, Ting-Ting Yu, Bin Liu, Liu-Gen Li, Mei-Fang Wang, Ning Han, Yong-Hong Xu, Chao Wang, Naoki Komatsu, Li Zhao, Xing-Chun Peng, Tong-Fei Li, Xiao Chen
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 937-949 (2022)
The present work aims to prove the concept of tumor-targeted drug delivery mediated by platelets. Doxorubicin (DOX) attached to nanodiamonds (ND-DOX) was investigated as the model payload drug of platelets. In vitro experiments first showed that ND-D
Externí odkaz:
https://doaj.org/article/f3b09e0ba9ae46919fc4ef7978ef0912
Autor:
Xiao-Xin Yang, Xiang Xu, Mei-Fang Wang, Hua-Zhen Xu, Xing-Chun Peng, Ning Han, Ting-Ting Yu, Liu-Gen Li, Qi-Rui Li, Xiao Chen, Yu Wen, Tong-Fei Li
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Chemodynamic therapy (CDT) relying on intracellular iron ions and H2O2 is a promising therapeutic strategy due to its tumor selectivity, which is limited by the not enough metal ions or H2O2 supply of tumor microenvironment. Herei
Externí odkaz:
https://doaj.org/article/1718d787c1ed46e49c6b39167ea5c3b3
Autor:
Hua-Zhen Xu, Tong-Fei Li, Chao Wang, Yan Ma, Yan Liu, Mei-Yan Zheng, Zhang-Jun-Yan Liu, Jin-Bo Chen, Ke Li, Shi-Kuan Sun, Naoki Komatsu, Yong-Hong Xu, Li Zhao, Xiao Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-24 (2021)
Abstract Background Tumor-associated macrophages (TAMs) are the most abundant stromal cells in the tumor microenvironment. Turning the TAMs against their host tumor cells is an intriguing therapeutic strategy particularly attractive for patients with
Externí odkaz:
https://doaj.org/article/d483002b0c34474cbc1bc0a1e9f3b471