Zobrazeno 1 - 10
of 865
pro vyhledávání: '"Tong Gao"'
Autor:
Jinhu Liu, Huajun Zhao, Tong Gao, Xinyan Huang, Shujun Liu, Meichen Liu, Weiwei Mu, Shuang Liang, Shunli Fu, Shijun Yuan, Qinglin Yang, Panpan Gu, Nan Li, Qingping Ma, Jie Liu, Xinke Zhang, Na Zhang, Yongjun Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Cytotherapy is a strategy to deliver modified cells to a diseased tissue, but targeting solid tumours remains challenging. Here we design macrophages, harbouring a surface glypican-3-targeting peptide and carrying a cargo to combat solid tum
Externí odkaz:
https://doaj.org/article/e0f6524a4aa747788c8e0d90890f216b
Autor:
Rui Chen, Xinyao Shi, Xiangrui Yao, Tong Gao, Guangyu Huang, Duo Ning, Zemin Cao, Youxin Xu, Weizheng Liang, Simon Zhongyuan Tian, Qionghua Zhu, Liang Fang, Meizhen Zheng, Yuhui Hu, Huanhuan Cui, Wei Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract CRISPR/Cas-based transcriptional activators can be enhanced by intrinsically disordered regions (IDRs). However, the underlying mechanisms are still debatable. Here, we examine 12 well-known IDRs by fusing them to the dCas9-VP64 activator, o
Externí odkaz:
https://doaj.org/article/ceef07aaa4ad422491da45a1b81f56bd
Autor:
Alina Sprenger-Svačina, Martin K. R. Svačina, Tong Gao, Rodney M. Ritzel, Louise D. McCullough, Kazim A. Sheikh, Gang Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe current study focuses on understanding the functional role of different subsets of endoneurial macrophages in autoimmune polyneuropathies (AP) and traumatic peripheral nerve injury (TPNI), which holds potential for clinical applicatio
Externí odkaz:
https://doaj.org/article/e2dbca4db85a45b68d916d1b933985fc
Autor:
Lin Cao, Yue Zhou, Shuai Lin, Chunyan Yang, Zixuan Guan, Xiaofan Li, Shujie Yang, Tong Gao, Jiazhen Zhao, Ning Fan, Yanan Song, Dongmin Li, Xiang Li, Zhuo Li, Feng Guan, Zengqi Tan
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Hepatocellular carcinoma (HCC) is a prevalent primary liver cancer often associated with chronic hepatitis B virus infection (CHB) and liver cirrhosis (LC), underscoring the critical need for biomarker discovery to improve patient outcomes.
Externí odkaz:
https://doaj.org/article/a052faee04894d5d966348f815b16327
Autor:
Zhi-Dong Zhang, Osezua Ibhadode, Shahriar Imani Shahabad, Xing-Yue Zhai, Dao-Yuan Yu, Tong Gao, Ji-Hong Zhu, Wei-Hong Zhang
Publikováno v:
Journal of Materials Research and Technology, Vol 30, Iss , Pp 6576-6595 (2024)
Laser powder bed fusion (LPBF) additive manufacturing (AM) broadens the horizons of design in academia and industry. However, LPBF contends with challenges like residual stresses and distortions due to uneven heating and cooling, leading to substanti
Externí odkaz:
https://doaj.org/article/db7044e661004467a2d855b79a7ebc21
Publikováno v:
Materials Research Letters, Vol 12, Iss 5, Pp 355-362 (2024)
A novel (8.5Al3BC + 14.5Al2O3)/Al composite was fabricated with exceptional elevated-temperature properties and stiffness. The composite boasts an average Young’s modulus of 99 GPa, with ultimate tensile strength and elongation of the composite at
Externí odkaz:
https://doaj.org/article/8ef03679794847aa8099b1e558bc84fc
Autor:
Huizhen Yang, Weiwei Mu, Shijun Yuan, Han Yang, Lili Chang, Xiao Sang, Tong Gao, Shuang Liang, Xiaoqing Liu, Shunli Fu, Zipeng Zhang, Yongjun Liu, Na Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Immune checkpoint inhibitors (ICIs) combined with antiangiogenic therapy have shown encouraging clinical benefits for the treatment of unresectable or metastatic hepatocellular carcinoma (HCC). Nevertheless, therapeutic efficacy and wide cli
Externí odkaz:
https://doaj.org/article/42ed710dee35490caf73fdc1ad5e65a0
Autor:
Xiao-Liang Wang, Xiangfei He, Tong Gao, Xinyu Zhou, Zobeida Cruz-Monserrate, Allan Tsung, Jianjie Ma, Chuanxi Cai
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102118- (2024)
Pancreatic ductal adenocarcinoma (PDAC) poses a formidable challenge in oncology due to its limited treatment options and poor long-term survival rates. Our previous work identified MG53, a member of the tripartite motif family protein (TRIM72), as a
Externí odkaz:
https://doaj.org/article/428077f6371d45f0b6084e5b72312785
Publikováno v:
International Journal of Digital Earth, Vol 17, Iss 1 (2024)
ABSTRACTMultispectral images make it possible to retrieve water quality parameters over a wide range and long time series by remote sensing. The robustness of traditional supervised machine learning models, which have been widely used, is affected in
Externí odkaz:
https://doaj.org/article/38adaf41eb064ed6a8ec666eb85a5ec5
Publikováno v:
Engineering Science and Technology, an International Journal, Vol 55, Iss , Pp 101755- (2024)
This study aims to enhance the performance of Proton Exchange Membrane Fuel Cell (PEMFC) by optimizing the design of a three-channel serpentine flow field. The focus is on the introduction of sub-channels beneath the flow field ribs, utilizing the pr
Externí odkaz:
https://doaj.org/article/6c88ae0fd2b843c6a0631c2a3b800d79