Surface Molecularly Engineered Mitochondria Conduct Immunophenotype Repolarization of Tumor‐Associated Macrophages to Potentiate Cancer Immunotherapy.

Autor: Zhang, Cai‐Ju^1,2 (AUTHOR), Li, Jia‐Mi^3,4 (AUTHOR), Xu, Dan⁵ (AUTHOR), Wang, Dan‐Dan³ (AUTHOR), Qi, Ming‐Hui³ (AUTHOR), Chen, Feng² (AUTHOR), Wu, Bo¹ (AUTHOR), Deng, Kai¹ (AUTHOR) deng-k@whu.edu.cn, Huang, Shi‐Wen^3,6 (AUTHOR) swhuang@whu.edu.cn

Publikováno v: Advanced Science. 10/16/2024, Vol. 11 Issue 38, p1-18. 18p.

Pyroglutamate-Amyloid-v and Glutaminyl Cyclase are Colocalized with Amyloid-v in Secretory Vesicles and Undergo Activity-Dependent, Regulated Secretion

Autor: Cynis, Holger, Funkelstein, Lydiane, Toneff, T., Mosier, C., Ziegler, M., Koch, Birgit, Demuth, Hans-Ulrich, Hook, V.

Background and Aims: N-truncated pyroglutamate (pGlu)-amyloid-v [Av(3-40/42)] peptides are key components that promote Av peptide accumulation, leading to neurodegeneration and memory loss in Alzheimer's disease. Because Av deposition in the brain oc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::9edf0c74afcbab10f186a78e26d62da1
https://publica.fraunhofer.de/handle/publica/237213

Enkephalins and Pain Modulation: Mechanisms of Action and Therapeutic Perspectives.

Autor: García-Domínguez, Mario¹ (AUTHOR) mario.gdominguez@ufv.es

Publikováno v: Biomolecules (2218-273X). Aug2024, Vol. 14 Issue 8, p926. 23p.

Metabolomics Analyses of 14 Classical Neurotransmitters by GC-TOF with LC-MS Illustrates Secretion of 9 Cell-Cell Signaling Molecules from Sympathoadrenal Chromaffin Cells in the Presence of Lithium.

Autor: Hook V; Skaggs School of Pharmacy and Pharmaceutical Sciences , University of California, San Diego , La Jolla , California 92093 , United States.; Department of Neurosciences and Department of Pharmacology, School of Medicine , University of California, San Diego , La Jolla , California 92093 , United States., Kind T; West Coast Metabolomics Center, UC Davis Genome Center , University of California, Davis , Davis , California 95616 , United States., Podvin S; Skaggs School of Pharmacy and Pharmaceutical Sciences , University of California, San Diego , La Jolla , California 92093 , United States., Palazoglu M; West Coast Metabolomics Center, UC Davis Genome Center , University of California, Davis , Davis , California 95616 , United States., Tran C; West Coast Metabolomics Center, UC Davis Genome Center , University of California, Davis , Davis , California 95616 , United States., Toneff T; Skaggs School of Pharmacy and Pharmaceutical Sciences , University of California, San Diego , La Jolla , California 92093 , United States., Samra S; West Coast Metabolomics Center, UC Davis Genome Center , University of California, Davis , Davis , California 95616 , United States., Lietz C; Skaggs School of Pharmacy and Pharmaceutical Sciences , University of California, San Diego , La Jolla , California 92093 , United States., Fiehn O; West Coast Metabolomics Center, UC Davis Genome Center , University of California, Davis , Davis , California 95616 , United States.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2019 Mar 20; Vol. 10 (3), pp. 1369-1379. Date of Electronic Publication: 2019 Jan 23.

Release of nontransmembrane full-length Alzheimer's amyloid precursor protein from the lumenar surface of chromaffin granule membranes

Autor: Tezapsidis, N. Li, H.-C. Ripellino, J.A. Efthimiopoulos, S. Vassilacopoulou, D. Sambamurti, K. Toneff, T. Yasothornsrikul, S. Hook, V.Y.H. Robakis, N.K.

We previously demonstrated the presence of a soluble form of full- length Alzheimer's amyloid precursor protein (APP) in the lumen of adrenal medullary chromaffin granules (CG). Furthermore, full-length APP is released from CG membranes in vitro at p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::091a602155652f357c6b6d47b6d61a94
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3096330