Constituintes químicos de Sebastiania macrocarpa Muell. Arg. (Euphorbiaceae) Chemical constituents from Sebastiania macrocarpa Muell. Arg. (Euphorbiaceae)

Autor: Michele A. A. Lima, Jefferson Q. Lima, Ângela M. C. Arriaga, Manoel Andrade-Neto, Gilvandete M. P. Santiago, Beatriz P. Bezerra, Yana S. Fereira, Helenicy N. H. Veras, Raimundo Braz-Filho

Publikováno v: Química Nova, Vol 32, Iss 2, Pp 348-353 (2009)

The chemical investigation of the methanolic extract of the aerial part of Sebastiania macrocarpa allowed the isolation of the mixture of steroids β-sitosterol and stigmasterol, gallic acid, and scopoletin. The hexane extract of the roots allowed th

Externí odkaz: https://doaj.org/article/91dc301632b745518446c122bd934bbe

Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives

Autor: Karsten Siems, Hannah Benson, Florenz Sasse, Gerald Dräger, Andreas Kirschning, Eike Kunst, Torsten Busch

Publikováno v: Organic and Biomolecular Chemistry 14 (2016), Nr. 38

The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines. © The Royal Society of Chemistry 2016.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba626ba297620109e2c09946fb16844
https://pubmed.ncbi.nlm.nih.gov/27604289

Towards the total synthesis of tonantzitlolone––preparation of key fragments and the complete carbon backbone

Autor: Rüdiger Wittenberg, Christian Beier, Gerald Dräger, Gerhard Jas, Holger Monenschein, Christian Jasper, Andreas Kirschning

Publikováno v: Tetrahedron Letters. 45:4457-4460

The first synthetic advances towards the novel diterpenoid tonantzitlolone 1 are described. The key steps in the synthesis involve a chromium(II) Reformatsky reaction, a diastereoselective C 1 extension and an expeditious aldol coupling step of two a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd09530abbbbb4ae0f7e7b8e8f13db85
https://doi.org/10.1016/j.tetlet.2004.04.056

Criblage d'activités biologiques de plantes endémiques ou indigènes de La Réunion - Recherche de molécules antivirales ciblant le virus du chikungunya

Autor: Techer, Sophie

Ce travail de thèse s'attache à identifier des plantes et/ou molécules à activités cytotoxique, antioxydante, anti-inflammatoire et antivirale ciblant le virus du chikungunya (CHIKV) dans le but de trouver des alternatives thérapeutiques vis-à

Externí odkaz: http://www.theses.fr/2013LARE0014/document

Constituintes químicos de Sebastiania macrocarpa Muell. Arg. (Euphorbiaceae)

Autor: Helenicy N. H. Veras, Ângela M.C. Arriaga, Jefferson Q. Lima, Gilvandete M. P. Santiago, Beatriz Pinheiro Bezerra, Raimundo Braz-Filho, Manoel Andrade-Neto, Yana S. Fereira, Michele A. A. Lima

Publikováno v: Química Nova v.32 n.2 2009
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Volume: 32, Issue: 2, Pages: 348-353, Published: 2009

The chemical investigation of the methanolic extract of the aerial part of Sebastiania macrocarpa allowed the isolation of the mixture of steroids β-sitosterol and stigmasterol, gallic acid, and scopoletin. The hexane extract of the roots allowed th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b40cea101fc2f57b14564de67815e95
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000200015