Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ton N.M. Schumacher"'
Autor:
Kristel Kemper, Oscar Krijgsman, Xiangjun Kong, Paulien Cornelissen-Steijger, Aida Shahrabi, Fleur Weeber, Daphne L. van der Velden, Onno B. Bleijerveld, Thomas Kuilman, Roel J.C. Kluin, Chong Sun, Emile E. Voest, Young Seok Ju, Ton N.M. Schumacher, A.F. Maarten Altelaar, Ultan McDermott, David J. Adams, Christian U. Blank, John B. Haanen, Daniel S. Peeper
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 263-277 (2016)
The therapeutic landscape of melanoma is improving rapidly. Targeted inhibitors show promising results, but drug resistance often limits durable clinical responses. There is a need for in vivo systems that allow for mechanistic drug resistance studie
Externí odkaz:
https://doaj.org/article/b4e20b0f1b48444f832fabb5c11f6dd8
Supplementary Figure Legends 1-2 from Skewing the T-Cell Repertoire by Combined DNA Vaccination, Host Conditioning, and Adoptive Transfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75cdc61fd057f968d4bf6b3c591c2bc
https://doi.org/10.1158/0008-5472.22375337
https://doi.org/10.1158/0008-5472.22375337
Supplementary Figure 1 from Skewing the T-Cell Repertoire by Combined DNA Vaccination, Host Conditioning, and Adoptive Transfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71769d2b4718e8c334651ea70bfeca6a
https://doi.org/10.1158/0008-5472.22375343.v1
https://doi.org/10.1158/0008-5472.22375343.v1
Supplementary Figure 2 from Skewing the T-Cell Repertoire by Combined DNA Vaccination, Host Conditioning, and Adoptive Transfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1b7c34f977ea579db1d1b12e993f04
https://doi.org/10.1158/0008-5472.22375340.v1
https://doi.org/10.1158/0008-5472.22375340.v1
Approaches for T-cell–based immunotherapy that have shown substantial effects in clinical trials are generally based on the adoptive transfer of high numbers of antigen-specific cells, and the success of these approaches is thought to rely on the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b67ad7b5668b18b5c225c4a0c774c9c
https://doi.org/10.1158/0008-5472.c.6497780.v1
https://doi.org/10.1158/0008-5472.c.6497780.v1
Publikováno v:
Cancer Discovery, 12(10), 2244-2248. AMER ASSOC CANCER RESEARCH
Summary: Tumor-specific cytotoxic T cells unleashed by the blockade of immune checkpoints have to overcome a hostile tumor microenvironment (TME). They start from very small numbers of T cells with tumor antigen specificity and, despite expansion, li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1996ce806bb9ca8f6d579332d66d9c5b
http://hdl.handle.net/1887/3566487
http://hdl.handle.net/1887/3566487
Publikováno v:
Trends in Immunology. 23:436-437
Autor:
Jeroen W.J. van Heijst, Koen Schepers, Erwin Swart, Carmen Gerlach, Ron M. Kerkhoven, Ramon Arens, Ton N.M. Schumacher
Publikováno v:
The Journal of Immunology. 178:S195-S195
Antigen-specific T cell responses are composed of phenotypically and functionally distinct subsets. However, it is often unclear how these subsets arise from a pool of naive T cells. To address such issues, we have developed a novel technique that al