Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tomoyuki Shono"'
Autor:
Akiteru Seki, Ryusuke Nagasawa, Ken-ichi Ogawara, Junsaku Kitagawa, Tomoya Ohno, Mark Bruce, Koji Shinozaki, Tomoyuki Shono, Takuya Nishio, Tatsuya Komagata, Hirotaka Tanaka, Hiroyuki Iida
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 379:400-408
Acromegaly is a chronic systemic disease characterized by facial and peripheral changes caused by soft tissue overgrowth, together with multiple complications. Despite available surgical and medical therapies, suitable treatments for acromegaly are s
Autor:
Tomoyuki Shono, Tohru Kambe, Masayuki Nakano, Yoshiyuki Yamaura, Akiteru Seki, Takayuki Maruyama, Hisao Nakai, Masaaki Toda, Toru Maruyama, Kiyoto Sakata
Publikováno v:
Chemicalpharmaceutical bulletin. 59(12)
Analogs 8-aza-16-aryl prostaglandin E(1) (PGE(1)) and 8-aza-5-thia-16-arylPGE(1) were synthesized and evaluated with respect to their subtype receptor affinity and EP4 agonist activity for the purposes of identifying subtype-selective EP4 agonists th