Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Tomoyuki Oe"'
Autor:
Yusuke Hatakawa, Rina Nakamura, Toshifumi Akizawa, Motomi Konishi, Akira Matsuda, Tomoyuki Oe, Motoaki Saito, Fumiaki Ito
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 586 (2024)
Despite the extensive research conducted on Alzheimer’s disease (AD) over the years, no effective drug for AD treatment has been found. Therefore, the development of new drugs for the treatment of AD is of the utmost importance. We recently reporte
Externí odkaz:
https://doaj.org/article/3dc6c8224bc8487d9553531a7e0cd4bb
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101268- (2022)
Amyloid beta (Aβ) proteins are produced from amyloid precursor protein cleaved by β- and γ-secretases, and are the main components of senile plaques pathologically found in Alzheimer's disease (AD) patient brains. Therefore, the relationship betwe
Externí odkaz:
https://doaj.org/article/6224879762ee4689bd024cb93e3e5f82
Mass spectrometry data from proteomic analysis of human skin keratins after exposure to UV radiation
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 100-106 (2016)
A mass spectrometry (MS)-based proteomic methodology was employed to monitor oxidative modifications in keratins, the main constituents of human skin (“Non-invasive proteomic analysis of human skin keratins: screening of methionine oxidation in ker
Externí odkaz:
https://doaj.org/article/c48dc360bc534b5d9bf7ce84e90fbfa6
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196050 (2018)
Pyridoxamine (PM) is a promising drug candidate for treating various chronic conditions/diseases in which oxidative stress and carbonyl compounds are important factors affecting pathogenicity. These abilities of PM are mainly attributed to its inhibi
Externí odkaz:
https://doaj.org/article/bffc7cfb27d548f39b40fe8e96dc3329
Publikováno v:
Toxicological Research. 39:147-156
Publikováno v:
Analytical biochemistry. 630
Angiotensin (Ang) peptides are the main effectors of the renin-angiotensin system (RAS) regulating diverse physiological conditions and are involved in renal and vascular diseases. Currently, quantitative analyses of Ang peptides in human plasma main
Publikováno v:
The Journal of Toxicological Sciences. 44:559-563
Acetaminophen (Paracetamol, APAP) has been widely used for many decades as an analgesic and antipyretic agent but APAP overdose often causes acute adverse reactions, particularly liver damage. The metabolically oxidized form of APAP, N-acetyl-p-benzo
Publikováno v:
Journal of proteome research. 19(9)
Proteins are continuously exposed to diverse chemical stresses, and the resulting chemical modifications can provide significant information on biological events. Keratins are the main constituent of human skin and are the major target proteins of va
Publikováno v:
Food chemistry. 333
Acrylamide (AA) is a toxic industrial chemical but is also found in heated potato foods such as French fries due to the Maillard reaction between amino acids and reducing sugars. However, high-temperature cooking is often required for flavoring, brow
Publikováno v:
International Journal of Mass Spectrometry. 468:116651
Proteins are continuously exposed to reactive chemical species owing to physiological and chemical stresses, resulting in various chemical modifications such as oxidation, nitration, glycation/glycoxidation, lipidation/lipoxidation, and adduct format