Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Tomoyuki Miyazaki"'
Autor:
Naoki Ikegaya, Honoka Nakamura, Yutaro Takayama, Yohei Miyake, Takahiro Hayashi, Masaki Sonoda, Mitsuru Sato, Kensuke Tateishi, Jun Suenaga, Masao Takaishi, Yu Kitazawa, Misako Kunii, Hiroki Abe, Tomoyuki Miyazaki, Tetsuaki Arai, Manabu Iwasaki, Takayuki Abe, Tetsuya Yamamoto
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION The use of anti‐epileptic drugs (AEDs) in degenerative dementia (DD) remains uncertain. We aimed to evaluate the association of early AED administration with subsequent DD occurrence. METHODS Using a large nationwide database,
Externí odkaz:
https://doaj.org/article/a9e3e85dd375488d89766625af530235
Autor:
Nami Masumoto, Shingo Kato, Masahiro Aichi, Sho Hasegawa, Kota Sahara, Kumiko Suyama, Akane Sano, Tomoyuki Miyazaki, Koji Okudela, Takeshi Kaneko, Takuya Takahashi
Publikováno v:
Thoracic Cancer, Vol 14, Iss 29, Pp 2897-2908 (2023)
Abstract Background Small cell lung cancer (SCLC) is a neuroendocrine tumor with poor prognosis. Neuroendocrine tumors possess characteristics of both nerve cells and hormone‐secreting cells; therefore, targeting the neuronal properties of these tu
Externí odkaz:
https://doaj.org/article/418c4c541dbf4c5191c29bc5273bfa0b
Autor:
Ryo Niikura, Tomoyuki Miyazaki, Kenkichi Takase, Hiroki Sasaguri, Takashi Saito, Takaomi C. Saido, Takahisa Goto
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-14 (2022)
Abstract As the proportion of elderly in society increases, so do the number of older patients undergoing surgical procedures. This is concerning as exposure to anesthesia has been identified as a risk factor for Alzheimer’s disease (AD). However,
Externí odkaz:
https://doaj.org/article/856d66431aba4d70ae9d543fef54654b
Autor:
Masayuki Nakano, Motokazu Koga, Tatsuo Hashimoto, Natsuki Matsushita, Daiki Masukawa, Yusuke Mizuno, Hiraku Uchimura, Ryo Niikura, Tomoyuki Miyazaki, Fumio Nakamura, Suo Zou, Takahiro Shimizu, Motoaki Saito, Kouichi Tamura, Takahisa Goto, Yoshio Goshima
Publikováno v:
Journal of Pharmacological Sciences, Vol 148, Iss 2, Pp 214-220 (2022)
Pulmonary hypertension (PH) is a severe and progressive disease that causes elevated right ventricular systolic pressure, right ventricular hypertrophy and ultimately right heart failure. However, the underlying pathophysiologic mechanisms are poorly
Externí odkaz:
https://doaj.org/article/0731879c0abe4c7cb92a39d3bebe47cb
Autor:
Mai Hatano, Tomoyuki Miyazaki, Yoshinobu Ishiwata, Waki Nakajima, Tetsu Arisawa, Yoko Kuroki, Ayako Kobayashi, Yuuki Takada, Matsuyoshi Ogawa, Kazunori Kawamura, Ming-Rong Zhang, Makoto Higuchi, Masataka Taguri, Yasuyuki Kimura, Takuya Takahashi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract [11C]K-2, a radiotracer exhibiting high affinity and selectivity for α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs), is suitable for the quantification of AMPARs in living human brains and potentially useful in the
Externí odkaz:
https://doaj.org/article/e64e9318174b4b25acffef4f39849587
Autor:
Hiromichi Wakui, Takahiro Yamaji, Kengo Azushima, Kazushi Uneda, Kotaro Haruhara, Akiko Nakamura, Kohji Ohki, Sho Kinguchi, Ryu Kobayashi, Shingo Urate, Toru Suzuki, Daisuke Kamimura, Shintaro Minegishi, Tomoaki Ishigami, Tomohiko Kanaoka, Kohei Matsuo, Tomoyuki Miyazaki, Tetsuya Fujikawa, Akio Yamashita, Kouichi Tamura
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Chronic kidney disease (CKD) progresses to end-stage renal failure via renal tubulointerstitial fibrosis. Malnutrition, inflammation, and arteriosclerosis interact to exacerbate the poor prognosis of CKD, and their effective management is th
Externí odkaz:
https://doaj.org/article/bfec8e8a9b8a42ca8255a052c924dad8
Autor:
Fumihiko Ueno, Takefumi Suzuki, Shinichiro Nakajima, Sachio Matsushita, Masaru Mimura, Tomoyuki Miyazaki, Takuya Takahashi, Hiroyuki Uchida
Publikováno v:
Neuropsychopharmacology Reports, Vol 39, Iss 3, Pp 148-155 (2019)
Abstract Background and Objectives Altered trafficking of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptors has been reported in postmortem studies and suggested the involvement of AMPA receptors in the pathophysiol
Externí odkaz:
https://doaj.org/article/f49afba1a05d454ea7a9ac33459de62b
Autor:
Yutaro Yamaoka, Kei Miyakawa, Sundararaj Stanleyraj Jeremiah, Rikako Funabashi, Koji Okudela, Sayaka Kikuchi, Junichi Katada, Atsuhiko Wada, Toshiki Takei, Mayuko Nishi, Kohei Shimizu, Hiroki Ozawa, Shuzo Usuku, Chiharu Kawakami, Nobuko Tanaka, Takeshi Morita, Hiroyuki Hayashi, Hideaki Mitsui, Keita Suzuki, Daisuke Aizawa, Yukihiro Yoshimura, Tomoyuki Miyazaki, Etsuko Yamazaki, Tadaki Suzuki, Hirokazu Kimura, Hideaki Shimizu, Nobuhiko Okabe, Hideki Hasegawa, Akihide Ryo
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 6, Pp 100311- (2021)
Summary: The ongoing coronavirus disease 2019 (COVID-19) pandemic is a major global public health concern. Although rapid point-of-care testing for detecting viral antigen is important for management of the outbreak, the current antigen tests are les
Externí odkaz:
https://doaj.org/article/fb0452d89f3141f5bf9c15493667baf5
Autor:
Atsushi Goto, Hirofumi Go, Kei Miyakawa, Yutaro Yamaoka, Norihisa Ohtake, Sousuke Kubo, Sundararaj Stanleyraj Jeremiah, Takahiro Mihara, Kotaro Senuki, Tomoyuki Miyazaki, Satoshi Ikeda, Takashi Ogura, Hideaki Kato, Ikuro Matsuba, Naoko Sanno, Masaaki Miyakawa, Haruo Ozaki, Masakazu Kikuoka, Yasuo Ohashi, Akihide Ryo, Takeharu Yamanaka
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Objective: There is scarce evidence regarding the long-term persistence of neutralizing antibodies among coronavirus disease 2019 (COVID-19) survivors. This study determined neutralizing antibody titers (NT50) and antibodies against spike protein (SP
Externí odkaz:
https://doaj.org/article/ce74df3f08c1470ba28b127ff7579ae5
Autor:
Akiko Doi, Tomoyuki Miyazaki, Takahiro Mihara, Maiko Ikeda, Ryo Niikura, Tomio Andoh, Takahisa Goto
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248113 (2021)
Immature neurons dominantly express the Na+-K+-2Cl- cotransporter isoform 1 (NKCC1) rather than the K+-Cl- cotransporter isoform 2 (KCC2). The intracellular chloride ion concentration ([Cl-]i) is higher in immature neurons than in mature neurons; the
Externí odkaz:
https://doaj.org/article/b2e4f45377c6401fbfc337731400717c