Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Tomoyuki Hamamoto"'
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Akademický článek
Exploitation of De Novo Helper-Lipids for Effective Gene Delivery.
Autor: Tomoaki Kurosaki, Takashi Kitahara, Mugen Teshima, Koyo Nishida, Junzo Nakamura, Mikiro Nakashima, Hideto To, Hiromitsu Hukuchi, Tomoyuki Hamamoto, Hitoshi Sasaki
Publikováno v: Journal of Pharmacy & Pharmaceutical Sciences, Vol 11, Iss 4 (2009)
Purpose: In gene delivery, a fusogenic lipid such as dioleyl phosphatidylethanolamine (DOPE) which is a component of cationic liposomal vector is important factor for effective transfection efficiency. We investigated the effect of penetration enhanc
Externí odkaz: https://doaj.org/article/389b5a1c1d534229b018f89336765923
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3
[Orolingual Angioedema after Recombinant Tissue Plasminogen Activator Treatment in Acute Cardiogenic Cerebral Embolism Patient Using Olmesartan: A Case Report]
Autor: Chisa Minami, Ryosuke Araki, Tomoyuki Hamamoto, Hideki Yamada
Publikováno v: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 142(1)
Recombinant tissue plasminogen activator (rt-PA), which is used to treat acute cerebral infarction, may cause angioedema immediately after administration particularly in patients who are taking angiotensin-converting enzyme (ACE) inhibitors. On the o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c062c9256944dd2b25dca5f52c8bd4
https://pubmed.ncbi.nlm.nih.gov/34980751
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4
Bcl-2/Bcl-xL inhibitor navitoclax increases the antitumor effect of Chk1 inhibitor prexasertib by inducing apoptosis in pancreatic cancer cells via inhibition of Bcl-xL but not Bcl-2
Autor: Yoshihito Morimoto, Masayoshi Hirohara, Kimihiko Takada, Kazuhiro Watanabe, Yutaka Masuda, Tomoyuki Hamamoto, Osamu Takeuchi
Publikováno v: Molecular and cellular biochemistry. 472(1-2)
In our previous study, we showed that prexasertib, a checkpoint kinase 1 (Chk1) inhibitor, enhances the effects of standard drugs for pancreatic cancer, including gemcitabine (GEM), S-1, and the combination of GEM and S-1 (GS). The combination of pre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c5b68a4e979f99c7f09f7d1255d3f6
https://pubmed.ncbi.nlm.nih.gov/32567031
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5
Anticholinergic load negatively correlates with recovery of cognitive activities of daily living for geriatric patients after stroke in the convalescent stage
Autor: Tomoyuki Hamamoto, Toshiyuki Hirai, Toshiichi Seki, Eiji Kose, Shinji Hidaka
Publikováno v: Journal of Clinical Pharmacy and Therapeutics. 43:799-806
What is known and objective Anticholinergic drugs are associated with risks of falls, confusion and cognitive dysfunction. However, the effect of anticholinergic drug use on rehabilitation outcomes after a stroke is poorly documented. We therefore ai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fa2beb6d6bfe87070d2b02fb9a7138
https://doi.org/10.1111/jcpt.12706
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8
Visualization and Analysis of Adverse Reactions of Molecularly Targeted Anticancer Agents Using the Self-organizing Map (SOM)
Autor: Tomoyuki Hamamoto, Kenichi Sato, Ayaka Serizawa, Kaori Ohtsuki, Junko Kawakami
Publikováno v: YAKUGAKU ZASSHI. 134:1069-1080
Molecularly targeted anticancer agents cause a variety of adverse reactions compared with conventional anticancer agents because of their unique mechanisms of action. Sources of drug information such as package inserts (PIs) provide primarily documen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2617a6c9fb5266c58ee2c50277cffb
https://doi.org/10.1248/yakushi.14-00145
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