Výsledky vyhledávání - "Tomoyuki, Ono"

Akademický článek

Effect of fenofibrate and selective PPARα modulator (SPPARMα), pemafibrate on KATP channel activity and insulin secretion

Autor: Shigeki Kitamura, Naoya Murao, Shoko Yokota, Masaru Shimizu, Tomoyuki Ono, Yusuke Seino, Atsushi Suzuki, Yuko Maejima, Kenju Shimomura

Publikováno v: BMC Research Notes, Vol 16, Iss 1, Pp 1-8 (2023)

Abstract Objective Insulin secretion is regulated by ATP-sensitive potassium (KATP) channels in pancreatic beta-cells. Peroxisome proliferator-activated receptors (PPAR) α ligands are clinically used to treat dyslipidemia. A PPARα ligand, fenofibra

Externí odkaz: https://doaj.org/article/16b4b294cf154b6cb024b62b129c2711

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Akademický článek

Traditional Japanese medicine Kamikihito ameliorates sucrose preference, chronic inflammation and obesity induced by a high fat diet in middle-aged mice

Autor: Yuko Maejima, Shoko Yokota, Megumi Yamachi, Shingen Misaka, Tomoyuki Ono, Hiroaki Oizumi, Keita Mizuno, Shizu Hidema, Katsuhiko Nishimori, Masato Aoyama, Heidi de Wet, Kenju Shimomura

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

The high prevalence of obesity has become a pressing global public health problem and there exists a strong association between increased BMI and mortality at a BMI of 25 kg/m2 or higher. The prevalence of obesity is higher among middle-aged adults t

Externí odkaz: https://doaj.org/article/188f3a3a00b84739acde88f84d0b71f7

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Akademický článek

Impact of Green Tea Catechin Ingestion on the Pharmacokinetics of Lisinopril in Healthy Volunteers

Autor: Shingen Misaka, Yuko Ono, Atsushi Uchida, Tomoyuki Ono, Osamu Abe, Hiroshi Ogata, Hideyuki Sato, Masahiko Suzuki, Satomi Onoue, Yayoi Shikama, Kenju Shimomura

Publikováno v: Clinical and Translational Science, Vol 14, Iss 2, Pp 476-480 (2021)

Lisinopril, a highly hydrophilic long‐acting angiotensin‐converting enzyme inhibitor, is frequently prescribed for the treatment of hypertension and congestive heart failure. Green tea consumption may reduce the risk of cardiovascular outcomes an

Externí odkaz: https://doaj.org/article/8ffee0fc0dfb4bab84c1da2a2c3ecaa5

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Akademický článek

Structure based analysis of KATP channel with a DEND syndrome mutation in murine skeletal muscle

Autor: Shoichiro Horita, Tomoyuki Ono, Saul Gonzalez-Resines, Yuko Ono, Megumi Yamachi, Songji Zhao, Carmen Domene, Yuko Maejima, Kenju Shimomura

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Abstract Developmental delay, epilepsy, and neonatal diabetes (DEND) syndrome, the most severe end of neonatal diabetes mellitus, is caused by mutation in the ATP-sensitive potassium (KATP) channel. In addition to diabetes, DEND patients present musc

Externí odkaz: https://doaj.org/article/f773962797f64e77ad79d1b308605126

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Identification of oxytocin receptor activating chemical components from traditional Japanese medicines

Autor: Yuko, Maejima, Shoichiro, Horita, Shoko, Yokota, Tomoyuki, Ono, Peter, Proks, Hiromi, Yoshida-Komiya, Yoichi, Ueta, Katsuhiko, Nishimori, Shingen, Misaka, Kenju, Shimomura

Publikováno v: Journal of Food and Drug Analysis. 29:653-675

Oxytocin (Oxt) is known to regulate social communication, stress and body weight. The activation of Oxt receptors (OTR) has clinical potential to abate stress disorders and metabolic syndrome. Kamikihito (KKT) is a traditional Japanese medicine used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504c3bbb9316f6c2d01ba0d8caf6a7c3
https://doi.org/10.38212/2224-6614.3381

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Double Valve Replacement After Ventricular Assist Device Implantation in a Fontan Patient

Autor: Hiromichi Sonoda, Shinichiro Oda, Tomoyuki Ono, Satoshi Fujita, Akira Shiose

Publikováno v: The Annals of Thoracic Surgery. 113:e437-e439

Few reports have described the implantation and management of an implantable ventricular assist device in patients with functional uni-ventricular anatomy. We herein report a case who underwent HVAD implantation due to severe cardiac dysfunction and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef5722db0602ad62731133c3a75c633a
https://doi.org/10.1016/j.athoracsur.2021.08.050

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