Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Tomoyuki, Kanamatsu"'
Publikováno v:
Neurochemistry International. 102:1-12
Microglia in the axotomized adult rat facial nucleus (axoFN) have been shown to highly express a glutamate transporter (GLT-1). The microglia appear to serve as glutamate (Glu) scavengers in the axoFN. However, there is no evidence that the microglia
Publikováno v:
Neuroscience Letters. 591:99-104
We previously verified that newborn rat brain-derived microglia have the ability to uptake (14)C-glutamate (Glu) through glutamate transporter-1. A given amount of Glu incorporated into microglia was suspected to be metabolized to glutamine (Gln). Ho
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 58:42-45
L-[4-(13)C]Glutamine was synthesized from sodium [2-(13)C]acetate in 12 steps and 18% overall yield. A Wittig reaction of (R)-benzyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate and ethyl 2-(triphenylphosphoranylidene)[2-(13)C]acetate prepared from
Autor:
Shingo Suzuki, Fumihiko Maekawa, Kohichi Tanaka, Keiko Suzuki, Hayato Sugiyama, Tomoharu Nakamori, Hiroko Ohki-Hamazaki, Tomoyuki Kanamatsu
Publikováno v:
Journal of Neurochemistry. 123:800-810
With the aim of elucidating the neural mechanisms of early learning, we studied the role of brain-derived neurotrophic factor (BDNF) in visual imprinting in birds. The telencephalic neural circuit connecting the visual Wulst and intermediate medial m
Autor:
Ken Fujiwara, Tomoharu Nakamori, Shinji Tsukahara, Kohichi Tanaka, Hiroko Ohki-Hamazaki, Tomoyuki Kanamatsu, Fumihiko Maekawa, Toshihiko Yada, Motoaki Uchimura
Publikováno v:
Journal of Neurochemistry. 102:1645-1657
Chick imprinting behavior is a good model for the study of learning and memory. Imprinting object is recognized and processed in the visual wulst, and the memory is stored in the intermediate medial mesopallium in the dorsal pallium of the telencepha
Autor:
Yasuo Katayama, Hiromitsu Orima, Seiji Okubo, Hironaka Igarashi, Daisuke Hasegawa, Tomoyuki Kanamatsu
Publikováno v:
Brain Research. 1143:221-227
FK-506 confers a neuroprotective effect and is thought to extend the time window for thrombolytic treatment of cerebral ischemia. These effects have not been assessed in an embolic stroke model. In addition, clinical studies have raised concern that
Glutamate metabolism in epilepsy: 13C-magnetic resonance spectroscopy observation in the human brain
Publikováno v:
NeuroReport. 16:2057-2060
To clarify changes in glutamate metabolism in the brain with chronic epileptic activities, 13C-magnetic resonance spectroscopy observation of glutamate and glutamine synthesis after oral administration of [1-13C] glucose (Glc C1) (0.75 g/kg) was perf
Autor:
Douglas L. Rothman, Robert G. Shulman, Anant B. Patel, Graeme F. Mason, Robin A. de Graaf, Tomoyuki Kanamatsu, Kevin L. Behar
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 24:972-985
13C nuclear magnetic resonance (NMR) experiments have previously shown that glutamatergic neurotransmitter flux (Vcycle(Glu/Gln)) changes proportionately with neuronal glucose oxidation (CMRglc(ox)N) in the nonactivated cortex of anesthetized rats. P
Autor:
Kokoro, Nagasawa, Atsushi, Kishida, Masahiro, Kajiwara, Tomoyuki, Kanamatsu, Kazuhiko, Takatori
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 58(2)
L-[4-(13)C]Glutamine was synthesized from sodium [2-(13)C]acetate in 12 steps and 18% overall yield. A Wittig reaction of (R)-benzyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate and ethyl 2-(triphenylphosphoranylidene)[2-(13)C]acetate prepared from
Autor:
Hiroyuki Sakagami, Tomoharu Nakamori, Kohichi Tanaka, Hiroko Ohki-Hamazaki, Tomoyuki Kanamatsu, Katsushige Sato, Masae Kinoshita
Publikováno v:
Journal of neurochemistry. 132(1)
Imprinting in chicks is a good model for elucidating the processes underlying neural plasticity changes during juvenile learning. We recently reported that neural activation of a telencephalic region, the core region of the hyperpallium densocellular