Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tomoyo Yoshinaga"'
Autor:
Tomoyo Yoshinaga, Kenichiro Uwabe, Shoichi Naito, Kenichi Higashino, Toru Nakano, Yoshito Numata, Akio Kihara
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167848 (2016)
Epithelial-mesenchymal transition (EMT) of renal tubular epithelial cells is one of the causative mechanisms of kidney fibrosis. In our study, we screened lipophilic compounds using a lipid library including approximately 200 lipids to identify those
Externí odkaz:
https://doaj.org/article/75d6453c0a144b8294dde6f7d044a2df
Quantifying Protein-Specific N-Glycome Profiles by Focused Protein and Immunoprecipitation Glycomics
Autor:
Goki Suda, Takuya Sho, Tomoyo Yoshinaga, Megumi Hato, Koji Ogawa, Yasuro Shinohara, Kenichi Higashino, Takashi Kobayashi, Kenichi Morikawa, Yoshito Numata, Jun-ichi Furukawa, Masato Nakai, Naoya Sakamoto, Hisatoshi Hanamatsu
Publikováno v:
Journal of proteome research. 18(8):3133-3141
Serum N-glycans have been reported to be potential diagnostic and therapeutic biomarkers for many diseases and conditions, such as inflammation, fibrosis, and cancer progression. We previously described the focused protein glycomic analysis (FPG) fro
Autor:
Tomoyo Yoshinaga, Takeshi Ishihara, Hiroko Togame, Maho Amano, Norimasa Iwasaki, Koji Takahashi, Hiroshi Takemoto, Shin-Ichiro Nishimura, Kiyoshi Kakiya, Akio Minami, Hiroto Miwa, Yoshikazu Tanaka, Takaomi Ito, Masatomo Rokushima
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1840:645-655
Background Osteoarthritis (OA) is one of the most common chronic diseases among adults, especially the elderly, which is characterized by destruction of the articular cartilage. Despite affecting more than 100 million individuals all over the world,
Autor:
Takami Akagi, Naoki Okada, Kazuhiko Matsuo, Atsushi Oda, Mitsuru Akashi, Yumiko Ishii, Tomoyo Yoshinaga, Shinsaku Nakagawa, Tomoaki Yoshikawa, Hiroyuki Kayamuro, Keisuke Matsuo
Publikováno v:
Vaccine. 26:1303-1313
Nanotechnology is a fundamental technology for designing and generating innovative carriers for biomacromolecular drugs. Biodegradable poly(gamma-glutamic acid)-based nanoparticles (gamma-PGA NPs) are excellent vaccine carriers capable of delivering
Autor:
Kenichi Higashino, Akio Kihara, Toru Nakano, Yoshito Numata, Tomoyo Yoshinaga, Shoichi Naito, Ken-Ichiro Uwabe
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167848 (2016)
PLoS ONE
PLoS ONE
Epithelial-mesenchymal transition (EMT) of renal tubular epithelial cells is one of the causative mechanisms of kidney fibrosis. In our study, we screened lipophilic compounds using a lipid library including approximately 200 lipids to identify those
Autor:
Shinsaku Nakagawa, Mai Yoshikawa, Tomoyo Yoshinaga, Yasuo Yoshioka, Tomoaki Yoshikawa, Kazuyuki Niki, Naoki Okada, Yohei Mukai, Keisuke Matsuo, Kazuhiko Matsuo
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(12)
We previously reported that poly (γ-glutamic acid)-based nanoparticles (γ-PGA NPs) are excellent vaccine carriers for inducing efficient cross-presentation in dendritic cells, thereby producing strong antitumor immunity in vivo. Analyzing the mecha
Autor:
Kazuhiko Matsuo, Shinsaku Nakagawa, Keisuke Matsuo, Naoki Okada, Tomoyo Yoshinaga, Yasuo Yoshioka, Mitsuru Akashi, Yohei Mukai, Yumiko Ishii
Publikováno v:
Biologicalpharmaceutical bulletin. 33(12)
Cytotoxic T-lymphocytes (CTLs) specific for tumor-associated antigens (TAAs) act in the immune surveillance system as major effector cells to eliminate malignant cells. Immunization with TAA-loaded dendritic cells (DCs) has great potential for treati