Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tomoyo Sawada"'
Autor:
Ethan Tietze, Andre Rocha Barbosa, Bruno Araujo, Veronica Euclydes, Bailey Spiegelberg, Hyeon Jin Cho, Yong Kyu Lee, Yanhong Wang, Alejandra McCord, Alan Lorenzetti, Arthur Feltrin, Joyce van de Leemput, Pasquale Di Carlo, Gianluca Ursini, Kynon J. Benjamin, Helena Brentani, Joel E. Kleinman, Thomas M. Hyde, Daniel R. Weinberger, Ronald McKay, Joo Heon Shin, Tomoyo Sawada, Apua C. M. Paquola, Jennifer A. Erwin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Primary human trophoblast stem cells (TSCs) and TSCs derived from human pluripotent stem cells (hPSCs) can potentially model placental processes in vitro. Yet, the pluripotent states and factors involved in the differentiation of hPSCs to TS
Externí odkaz:
https://doaj.org/article/6bb7441979f6437cb464f3a0916c266a
Autor:
Kaori Sawada, Tomoyo Sawada, Tadahiro Kobayashi, Akiko Fujiki, Takashi Matsushita, Shigeru Kawara, Kentaro Izumi, Wataru Nishie, Hiroshi Shimizu, Kazuhiko Takehara, Yasuhito Hamaguchi
Publikováno v:
Immunological Medicine, Vol 44, Iss 1, Pp 53-55 (2021)
Bullous pemphigoid (BP) is a cutaneous autoimmune blistering disorder. Recently, it has been reported that dipeptidyl peptidase-4 inhibitors (DPP4i) is associated with the development of BP (DPP4i-BP). Patients with DPP4i-BP have autoantibodies (auto
Externí odkaz:
https://doaj.org/article/188aacc15f304d18a8c4ef9f1d2b69f1
Autor:
Tomoyo Sawada, Kynon J.M. Benjamin, Anna C. Brandtjen, Ethan Tietze, Samuel J. Allen, Apuã C.M. Paquola, Joel E. Kleinman, Thomas M. Hyde, Jennifer A. Erwin
Publikováno v:
Stem Cell Research, Vol 46, Iss , Pp 101806- (2020)
In this study, we established induced pluripotent stem (iPS) cell lines from postmortem dura-derived fibroblasts of four control individuals with low polygenic risk score for psychiatric disorders including schizophrenia and bipolar disorder. The fib
Externí odkaz:
https://doaj.org/article/b9f6ef4714e54a639760efb76d5718e3
Autor:
Tomoko Kanao, Tomoyo Sawada, Shireen-Anne Davies, Hiroshi Ichinose, Kazuko Hasegawa, Ryosuke Takahashi, Nobutaka Hattori, Yuzuru Imai
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30958 (2012)
Activation of the forkhead box transcription factor FoxO is suggested to be involved in dopaminergic (DA) neurodegeneration in a Drosophila model of Parkinson's disease (PD), in which a PD gene product LRRK2 activates FoxO through phosphorylation. In
Externí odkaz:
https://doaj.org/article/9a7b8e49f3524278bb298715201f3b01
Autor:
Song Liu, Tomoyo Sawada, Seongsoo Lee, Wendou Yu, George Silverio, Philomena Alapatt, Ivan Millan, Alice Shen, William Saxton, Tomoko Kanao, Ryosuke Takahashi, Nobutaka Hattori, Yuzuru Imai, Bingwei Lu
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002537 (2012)
Mutations in Pten-induced kinase 1 (PINK1) are linked to early-onset familial Parkinson's disease (FPD). PINK1 has previously been implicated in mitochondrial fission/fusion dynamics, quality control, and electron transport chain function. However, i
Externí odkaz:
https://doaj.org/article/4ddc5e023a0a462b8d1a24398e510dd1
Autor:
Yuzuru Imai, Tomoko Kanao, Tomoyo Sawada, Yoshito Kobayashi, Yasuhiro Moriwaki, Yosuke Ishida, Kohsuke Takeda, Hidenori Ichijo, Bingwei Lu, Ryosuke Takahashi
Publikováno v:
PLoS Genetics, Vol 6, Iss 12, p e1001229 (2010)
PTEN-induced kinase 1 (PINK1), which is required for mitochondrial homeostasis, is a gene product responsible for early-onset Parkinson's disease (PD). Another early onset PD gene product, Parkin, has been suggested to function downstream of the PINK
Externí odkaz:
https://doaj.org/article/7b5f21c360034393b1c9a28a38dd3445
Autor:
Tomoyo Sawada, André Barbosa, Bruno Araujo, Alejandra E. McCord, Laura D’Ignazio, Kynon J. M. Benjamin, Arthur Feltrin, Ria Arora, Anna C. Brandtjen, Joel E. Kleinman, Thomas M. Hyde, Daniel R. Weinberger, Apuā C. M. Paquola, Jennifer A. Erwin
Schizophrenia (SCZ) is a brain disorder originating during neurodevelopment with complex genetic and environmental etiologies. Despite decades of clinical evidence of altered striatal function in affected patients, its cellular and molecular underpin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2dc2d603cf397a640ae9ce965d09afd
https://doi.org/10.1101/2022.05.26.493589
https://doi.org/10.1101/2022.05.26.493589
Autor:
Laura D’Ignazio, Ricardo S. Jacomini, Bareera Qamar, Kynon J.M. Benjamin, Ria Arora, Tomoyo Sawada, Taylor A. Evans, Kenneth E. Diffenderfer, Aimee R. Pankonin, William T. Hendriks, Thomas M Hyde, Joel E Kleinman, Daniel R Weinberger, D. Cristopher Bragg, Apua C.M. Paquola, Jennifer A. Erwin
X-linked Dystonia-Parkinsonism (XDP) is an inherited, X-linked, adult-onset movement disorder characterized by degeneration in the neostriatum. No therapeutics alter disease progression. The mechanisms underlying regional differences in degeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea5bc19d9e05ce56a97aa3006635520c
https://doi.org/10.1101/2022.03.26.485862
https://doi.org/10.1101/2022.03.26.485862
Autor:
Shigeru Kawara, Wataru Nishie, Tadahiro Kobayashi, Akiko Fujiki, Kaori Sawada, Tomoyo Sawada, Hiroshi Shimizu, Yasuhito Hamaguchi, Kazuhiko Takehara, Kentaro Izumi, Takashi Matsushita
Publikováno v:
Immunological Medicine, Vol 44, Iss 1, Pp 53-55 (2021)
Bullous pemphigoid (BP) is a cutaneous autoimmune blistering disorder. Recently, it has been reported that dipeptidyl peptidase-4 inhibitors (DPP4i) is associated with the development of BP (DPP4i-BP). Patients with DPP4i-BP have autoantibodies (auto
Autor:
Joo Heon Shin, Jennifer A. Erwin, Joyce van de Leemput, Ethan Tietze, Hyeon Jin Cho, Pasquale Di Carlo, Yong-kyu Lee, Joel E. Kleinman, Kynon J.M. Benjamin, Helena Brentani, Veronica Euclydes, Tomoyo Sawada, Apuã C. M. Paquola, Andre Rocha Barbosa, Arthur Sant’Anna Feltrin, Gianluca Ursini, Ronald D. G. McKay, Thomas M. Hyde, Daniel R. Weinberger
SummaryThe human placenta is increasingly a focus of research related to early child development and the impact of maternal hyperimmune states. The ability to model human trophectoderm disease states from human pluripotent stem cells, the nature of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c12270c697dd72e563102e7d31d1264
https://doi.org/10.1101/2020.08.29.273425
https://doi.org/10.1101/2020.08.29.273425