Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Tomoyo Hashiguchi"'
Autor:
Suguru Yamasaki, Hung-Ya Tu, Take Matsuyama, Matsuri Horiuchi, Tomoyo Hashiguchi, Junki Sho, Atsushi Kuwahara, Akiyoshi Kishino, Toru Kimura, Masayo Takahashi, Michiko Mandai
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103657- (2022)
Summary: Pluripotent stem cell (PSC)-derived retinal sheet transplanted in vivo can form structured photoreceptor layers, contact with host bipolar cells, and transmit light signals to host retinas. However, a major concern is the presence of graft b
Externí odkaz:
https://doaj.org/article/f2cca607881b4837bbc6d9a9d51e2a11
Autor:
Take Matsuyama, Hung-Ya Tu, Jianan Sun, Tomoyo Hashiguchi, Ryutaro Akiba, Junki Sho, Momo Fujii, Akishi Onishi, Masayo Takahashi, Michiko Mandai
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102866- (2021)
Summary: ESC/iPSC-retinal sheet transplantation, which supplies photoreceptors as well as other retinal cells, has been shown to be able to restore visual function in mice with end-stage retinal degeneration. Here, by introducing a novel type of gene
Externí odkaz:
https://doaj.org/article/a66400a246a743b58dabb3fdb6bb53fd
Autor:
Hung-Ya Tu, Takehito Watanabe, Hiroshi Shirai, Suguru Yamasaki, Masaharu Kinoshita, Keizo Matsushita, Tomoyo Hashiguchi, Hirotaka Onoe, Take Matsuyama, Atsushi Kuwahara, Akiyoshi Kishino, Toru Kimura, Mototsugu Eiraku, Kiyoshi Suzuma, Takashi Kitaoka, Masayo Takahashi, Michiko Mandai
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 562-574 (2019)
Background: We have previously reported that xeno-transplanted human ESC-derived retinas are able to mature in the immunodeficient retinal degeneration rodent models, similar to allo-transplantations using mouse iPSC-derived retina. The photoreceptor
Externí odkaz:
https://doaj.org/article/9426142104d94319966b4aa705aca802
Autor:
Ryutaro Akiba, Take Matsuyama, Hung-Ya Tu, Tomoyo Hashiguchi, Junki Sho, Shuichi Yamamoto, Masayo Takahashi, Michiko Mandai
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Quantitative and qualitative evaluation of synapses is crucial to understand neural connectivity. This is particularly relevant now, in view of the recent advances in regenerative biology and medicine. There is an urgent need to evaluate synapses to
Externí odkaz:
https://doaj.org/article/6011b284d0a44b4e9670446ab4da9302
Autor:
Michiko Mandai, Momo Fujii, Tomoyo Hashiguchi, Genshiro A. Sunagawa, Shin-ichiro Ito, Jianan Sun, Jun Kaneko, Junki Sho, Chikako Yamada, Masayo Takahashi
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 1112-1113 (2017)
Externí odkaz:
https://doaj.org/article/2b70c08485f84c278e6f6597c118e8d1
Autor:
Masayo Takahashi, Junki Sho, Jianan Sun, Take Matsuyama, Tomoyo Hashiguchi, Akishi Onishi, Momo Fujii, Ryutaro Akiba, Michiko Mandai, Hung-Ya Tu
Publikováno v:
iScience
iScience, Vol 24, Iss 8, Pp 102866-(2021)
iScience, Vol 24, Iss 8, Pp 102866-(2021)
Summary ESC/iPSC-retinal sheet transplantation, which supplies photoreceptors as well as other retinal cells, has been shown to be able to restore visual function in mice with end-stage retinal degeneration. Here, by introducing a novel type of genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18368e9880a633ef18cbe64324858f14
https://pubmed.ncbi.nlm.nih.gov/34409267
https://pubmed.ncbi.nlm.nih.gov/34409267
Autor:
Take Matsuyama, Hung-Ya Tu, Michiko Mandai, Momo Fujii, Masayo Takahashi, Junki Sho, Tomoyo Hashiguchi, Jianan Sun, Ryutaro Akiba, Akishi Onishi
ES/iPS-retinal sheet transplantation, which supplies photoreceptors as well as other retinal cells, has been shown able to restore visual function in mice with end-stage retinal degeneration. Here, by introducing a novel type of genetically engineere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ca6634bea679ee4c0b706aaebbd4bd
https://doi.org/10.1101/2020.12.23.424068
https://doi.org/10.1101/2020.12.23.424068
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Retinal ganglion cell (RGC) transplantation is a therapeutic approach to replace irreversibly degenerated RGCs in diseases such as glaucoma. However, the application of primary RGCs is limited by the availability of tissues. The goal of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28110fdf1c276e50c1da8ce92d252eed
https://doi.org/10.1167/iovs.62.13.26
https://doi.org/10.1167/iovs.62.13.26
Autor:
Hung-Ya Tu, Takashi Kitaoka, Toru Kimura, Michiko Mandai, Tomoyo Hashiguchi, Hiroshi Shirai, Keizo Matsushita, Takehito Watanabe, Mototsugu Eiraku, Masayo Takahashi, Atsushi Kuwahara, Masaharu Kinoshita, Akiyoshi Kishino, Take Matsuyama, Hirotaka Onoe, Suguru Yamasaki, Kiyoshi Suzuma
Publikováno v:
EBioMedicine
Background We have previously reported that xeno-transplanted human ESC-derived retinas are able to mature in the immunodeficient retinal degeneration rodent models, similar to allo-transplantations using mouse iPSC-derived retina. The photoreceptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a02a7bcb286ca6fd0ff20888300a84d
https://pubmed.ncbi.nlm.nih.gov/30502055
https://pubmed.ncbi.nlm.nih.gov/30502055
Autor:
Tomoyo Hashiguchi, Michiko Mandai, Yuko Iwasaki, Kyoko Iseki, S. Okamoto, Naoko Hayashi, Masayo Takahashi, Hiroyuki Kamao, Sunao Sugita
Publikováno v:
Investigative Ophthalmology & Visual Science. 56:1051-1062
PURPOSE The purpose of this study was to determine whether human retinal pigment epithelial (RPE) cells from induced pluripotent stem (iPS) cells could inhibit T-cell activation in vitro. METHODS Cultured iPS-derived RPE (iPS-RPE) cells were establis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add2ae33d38f4ec0a566af799df2fcdb
https://doi.org/10.1167/iovs.14-15619
https://doi.org/10.1167/iovs.14-15619