Zobrazeno 1 - 10 of 108 pro vyhledávání: '"Tomoyasu Sugiyama"'
1
Akademický článek
Finding new roles of classic biomolecular condensates in the nucleus: Lessons from fission yeast
Autor: Tomoyasu Sugiyama
Publikováno v: Cell Insight, Vol 3, Iss 5, Pp 100194- (2024)
Decades have passed since the initial discovery of membrane-less nuclear compartments, commonly called nuclear bodies or nuclear condensates. These compartments have drawn attention to their unique characteristics and functions, especially after intr
Externí odkaz: https://doaj.org/article/bd07992fc2714799a522ac1d69f8f867
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2
Akademický článek
Temporal and Locational Values of Images Affecting the Deep Learning of Cancer Stem Cell Morphology
Autor: Yumi Hanai, Hiroaki Ishihata, Zaijun Zhang, Ryuto Maruyama, Tomonari Kasai, Hiroyuki Kameda, Tomoyasu Sugiyama
Publikováno v: Biomedicines, Vol 10, Iss 5, p 941 (2022)
Deep learning is being increasingly applied for obtaining digital microscopy image data of cells. Well-defined annotated cell images have contributed to the development of the technology. Cell morphology is an inherent characteristic of each cell typ
Externí odkaz: https://doaj.org/article/eb00c9e6dbdc45d4a4fdfdb2227aa3fa
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3
Akademický článek
Deep Learning of Cancer Stem Cell Morphology Using Conditional Generative Adversarial Networks
Autor: Saori Aida, Junpei Okugawa, Serena Fujisaka, Tomonari Kasai, Hiroyuki Kameda, Tomoyasu Sugiyama
Publikováno v: Biomolecules, Vol 10, Iss 6, p 931 (2020)
Deep-learning workflows of microscopic image analysis are sufficient for handling the contextual variations because they employ biological samples and have numerous tasks. The use of well-defined annotated images is important for the workflow. Cancer
Externí odkaz: https://doaj.org/article/b83604879e1b4a418cf5c59e05f4f06d
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4
Akademický článek
The Catalytic-Dependent and -Independent Roles of Lsd1 and Lsd2 Lysine Demethylases in Heterochromatin Formation in Schizosaccharomyces pombe
Autor: Bahjat F. Marayati, James F. Tucker, David A. De La Cerda, Tien-Chi Hou, Rong Chen, Tomoyasu Sugiyama, James B. Pease, Ke Zhang
Publikováno v: Cells, Vol 9, Iss 4, p 955 (2020)
In eukaryotes, heterochromatin plays a critical role in organismal development and cell fate acquisition, through regulating gene expression. The evolutionarily conserved lysine-specific demethylases, Lsd1 and Lsd2, remove mono- and dimethylation on
Externí odkaz: https://doaj.org/article/68b1c4342f38417e8fb0bd90b3e5947a
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5
Akademický článek
Rhn1, a nuclear protein, is required for suppression of meiotic mRNAs in mitotically dividing fission yeast.
Autor: Tomoyasu Sugiyama, Rie Sugioka-Sugiyama, Kazumasa Hada, Ryusuke Niwa
Publikováno v: PLoS ONE, Vol 7, Iss 8, p e42962 (2012)
In the fission yeast Schizosaccharomyces pombe, many meiotic mRNAs are transcribed during mitosis and meiosis and selectively eliminated in mitotic cells. However, this pathway for mRNA decay, called the determinant of selective removal (DSR)-Mmi1 sy
Externí odkaz: https://doaj.org/article/ee7adba42c884ae1a39596c96de3b6fd
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7
Deep Learning of Phase-Contrast Images of Cancer Stem Cells Using a Selected Dataset of High Accuracy Value Using Conditional Generative Adversarial Networks
Autor: Zaijun Zhang, Hiroaki Ishihata, Ryuto Maruyama, Tomonari Kasai, Hiroyuki Kameda, Tomoyasu Sugiyama
Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5323
Artificial intelligence (AI) technology for image recognition has the potential to identify cancer stem cells (CSCs) in cultures and tissues. CSCs play an important role in the development and relapse of tumors. Although the characteristics of CSCs h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea368a98c4a7637a7d0876123bdd1b40
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10
Effects of the anti-inflammatory drug celecoxib on cell death signaling in human colon cancer
Autor: Ryuto Maruyama, Yuki Kiyohara, Tomoyasu Sugiyama
The anti-inflammatory drug celecoxib, the only inhibitor of cyclooxygenase-2 (COX-2) with anticancer activity, is used to treat rheumatoid arthritis and can cause endoplasmic reticulum (ER) stress by inhibiting sarco/ER Ca2 + -ATPase activity in canc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d3efbc52e099082e27b0cabb66e3e5b
https://doi.org/10.21203/rs.3.rs-2082790/v1
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