Výsledky vyhledávání - "Tomoya Sakabe"

Akademický článek

High Efficacy of Preoperative Low-Dose Radiotherapy with Sanazole (AK-2123) for Extraskeletal Ewing's Sarcoma: A Case Report

Autor: Tomoya Sakabe, Hiroaki Murata, Eiichi Konishi, Kazutaka Koto, Naoyuki Horie, Takaaki Matsui, Yasushi Sawai, Hideya Yamazaki, Tsutomu V. Kagiya, Toshikazu Kubo

Publikováno v: Sarcoma, Vol 2011 (2011)

Extraskeletal Ewing's sarcoma is a rare soft tissue tumor that is morphologically indistinguishable from Ewing's sarcoma of bone. We report a case of extraskeletal Ewing's sarcoma with several systemic problems. A 69-year-old man presented with a 5-m

Externí odkaz: https://doaj.org/article/936f4bb420f64d7c9bcf70943b1a41cb

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Transcription factor scleraxis vitally contributes to progenitor lineage direction in wound healing of adult tendon in mice

Autor: Nao Furuta, Tomoya Sakabe, Takako Sasaki, Takao Sakai, Ataru Sunaga, Keiko Sakai, Toru Maeda, Ronen Schweitzer

Publikováno v: The Journal of Biological Chemistry
The Journal of biological chemistry

Tendon is a dense connective tissue that transmits high mechanical forces from skeletal muscle to bone. The transcription factor scleraxis (Scx) is a highly specific marker of both precursor and mature tendon cells (tenocytes). Mice lacking scx exhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9d097012e1ecfef5a24bafd992ca97
https://doi.org/10.1074/jbc.ra118.001987

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Magnetic resonance imaging and thallium-201 scintigraphy for the diagnosis of localized pigmented villonodular synovitis arising from the elbow: A case report and review of the literature

Autor: Hiroaki Murata, Yasushi Sawai, Naoyuki Horie, Tomoya Sakabe, Toshikazu Kubo, Takaaki Matsui, Yoshiro Tsuji, Kazutaka Koto

Publikováno v: Experimental and Therapeutic Medicine

Pigmented villonodular synovitis (PVNS) arising from the elbow joint is extremely rare; only 24 cases have been reported. It is extremely difficult to differentiate PVNS from other soft tissue tumors on the basis of imaging findings alone. Therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3035b84ad276f66922cc723d1f8097ca
https://doi.org/10.3892/etm.2013.1022

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Chondrosarcoma from the sternum: Reconstruction with titanium mesh and a transverse rectus abdominis myocutaneous flap after subtotal sternal excision

Autor: Hiroaki Murata, Naoyuki Horie, Tomoya Sakabe, Toshihiro Ishida, Toshikazu Kubo, Eiichi Konishi, Kazuteru Ryu, Shinichiro Nakamura, Kazutaka Koto

Publikováno v: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

Summary Background Chondrosarcoma arising from the sternum is extremely rare and is often untreatable. Removal of the sternum for malignant tumor results in large defects in bone and soft tissue, causing deformity and paradoxical movement of the ches

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd29613e9fb5e60c40bb8e6b756c03ec
http://europepmc.org/articles/PMC3560565

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Musculoskeletal diseases--tendon

Autor: Tomoya Sakabe, Takao Sakai

Publikováno v: British Medical Bulletin. 99:211-225

Introduction: Tendons establish specific connections between muscles and the skeleton by transferring contraction forces from skeletal muscle to bone thereby allowing body movement. Tendon physiology and pathology are heavily dependent on mechanical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33c503c652b66288182b552dd25734c
https://doi.org/10.1093/bmb/ldr025

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Conversion of Mechanical Force into TGF-β-Mediated Biochemical Signals

Autor: Dusko Ilic, Harihara Baskaran, Douglas R. Keene, Alexander L. Rivera, Takao Sakai, Joseph P. Iannotti, Toru Maeda, Ataru Sunaga, Edward Stavnezer, Tomoya Sakabe, Takako Sasaki, Keiko Sakai, Ronen Schweitzer

Publikováno v: Current Biology. 21:933-941

Summary Mechanical forces influence homeostasis in virtually every tissue [1, 2]. Tendon, constantly exposed to variable mechanical force, is an excellent model in which to study the conversion of mechanical stimuli into a biochemical response [3–5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71453a4e3f188c4ab8c3f6605ed34c7c
https://doi.org/10.1016/j.cub.2011.04.007

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Combined effects of a third-generation bisphosphonate, zoledronic acid with other anticancer agents against murine osteosarcoma

Autor: Shinya Kimura, Toshikazu Kubo, Taira Maekawa, Hiroaki Murata, Hideyuki Takeshita, Takaaki Matsui, Naoyuki Horie, Tomoya Sakabe, Shinji Fushiki

Publikováno v: British Journal of Cancer

Bisphosphonates (BPs) are widely used to treat bone diseases and also appear to possess direct antitumour activity. We have previously reported that third-generation BPs such as zoledronic acid (ZOL) and minodronic acid (YM529) synergistically augmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb710a260c450c5c66bf572604ed691
https://doi.org/10.1038/sj.bjc.6603548

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Chromosomal imbalances in adult T-cell leukemia revealed by comparative genomic hybridization: gains at 14q32 and 2p16-22 in cell lines

Autor: Yoji Ariyama, Johji Inazawa, Yusuke Nakamura, Takashi Shinomiya, Toshiki Mori, Akihisa Kanamaru, Tomoya Sakabe, Yoji Fukuda, Masao Seto, Masaharu Isobe, Yasuaki Yamada

Publikováno v: Journal of Human Genetics. 44:357-363

Comparative genomic hybridization was used to identify chromosomal imbalances in eight cell lines and 12 blood samples from patients with adult T-cell leukemia/lymphoma (ATL). The chromosomes most often over-represented in the cell lines were 2p (6 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9630aed9e20f2356d27cc2c79dfb75
https://doi.org/10.1007/s100380050178

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Gains, losses, and amplifications of genomic materials in primary gastric cancers analyzed by comparative genomic hybridization

Autor: Chouhei Sakakura, Yusuke Nakamura, Toshio Takahashi, Akeo Hagiwara, Johji Inazawa, Toshiki Mori, Tomoya Sakabe, Yoji Ariyama, Kosei Date, Takashi Shinomiya, Tatsuo Abe, Toshiharu Yamaguchi

Publikováno v: Genes, Chromosomes and Cancer. 24:299-305

By means of comparative genomic hybridization (CGH), we screened 58 primary gastric cancers for changes in copy number of DNA sequences. We detected frequent losses on Ip32-33 (21%), 3p21-23 (22%), 5q14-22 (36%), 6q16 (26%), 9p21-24 (22%), 16q (21%),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb2b53ce669ee20f41bfc296998b0da
https://doi.org/10.1002/(sici)1098-2264(199904)24:4<299::aid-gcc2>3.0.co

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