Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Tomoya S. Kitajima"'
Autor:
Anna Kouznetsova, Sonata Valentiniene, Jian-Guo Liu, Tomoya S. Kitajima, Hjalmar Brismar, Christer Höög
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Correct chromosome segregation is essential to preserve genetic integrity. The two protein kinases, Aurora B and its meiotic homolog Aurora C, regulate attachments between chromosomal kinetochores and microtubules, thereby contributing to the accurac
Externí odkaz:
https://doaj.org/article/c682a469ba3248ec81f3677b7768f607
Autor:
Shuhei Yoshida, Sui Nishiyama, Lisa Lister, Shu Hashimoto, Tappei Mishina, Aurélien Courtois, Hirohisa Kyogoku, Takaya Abe, Aki Shiraishi, Meenakshi Choudhary, Yoshiharu Nakaoka, Mary Herbert, Tomoya S. Kitajima
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Oocyte meiosis must achieve spindle bipolarization without predefined spatial cues. Yoshida et al. demonstrate that spindle bipolarization during meiosis I in mouse oocytes requires kinetochores to prevent chromosome segregation errors, a phenomenon
Externí odkaz:
https://doaj.org/article/846a65e485104228b1fc63d20e3f1d9c
Autor:
Shuhei Nakamura, Masaki Oba, Mari Suzuki, Atsushi Takahashi, Tadashi Yamamuro, Mari Fujiwara, Kensuke Ikenaka, Satoshi Minami, Namine Tabata, Kenichi Yamamoto, Sayaka Kubo, Ayaka Tokumura, Kanako Akamatsu, Yumi Miyazaki, Tsuyoshi Kawabata, Maho Hamasaki, Koji Fukui, Kazunori Sango, Yoshihisa Watanabe, Yoshitsugu Takabatake, Tomoya S. Kitajima, Yukinori Okada, Hideki Mochizuki, Yoshitaka Isaka, Adam Antebi, Tamotsu Yoshimori
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Autophagic activity decreases with age via unknown mechanisms. Here the authors show that expression of the negative autophagy regulator Rubicon increases with age, that its genetic ablation improves lifespan and ameliorates a number of age-associate
Externí odkaz:
https://doaj.org/article/8aa18fda9b7a4cc7bd3ad05d003b9c17
Autor:
Meng-Tsen Ke, Yasuhiro Nakai, Satoshi Fujimoto, Rie Takayama, Shuhei Yoshida, Tomoya S. Kitajima, Makoto Sato, Takeshi Imai
Publikováno v:
Cell Reports, Vol 14, Iss 11, Pp 2718-2732 (2016)
Super-resolution imaging deep inside tissues has been challenging, as it is extremely sensitive to light scattering and spherical aberrations. Here, we report an optimized optical clearing agent for high-resolution fluorescence imaging (SeeDB2). SeeD
Externí odkaz:
https://doaj.org/article/4a3bda8de5044ed9bbed38d61c32e337
Autor:
Hirohisa KYOGOKU, Tomoya S KITAJIMA
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 1, Pp 1-9 (2022)
The study of the size of cells and organelles has a long history, dating back to the 1600s when cells were defined. In particular, various methods have elucidated the size of the nucleus and the mitotic spindle in several species. However, little res
Externí odkaz:
https://doaj.org/article/a178d8f0d7e347bda65cc31c8195a76c
Autor:
Kenta Murakami, Nobuhiko Hamazaki, Norio Hamada, Go Nagamatsu, Ikuhiro Okamoto, Hiroshi Ohta, Yoshiaki Nosaka, Yukiko Ishikura, Tomoya S. Kitajima, Yuichiro Semba, Yuya Kunisaki, Fumio Arai, Koichi Akashi, Mitinori Saitou, Kiyoko Kato, Katsuhiko Hayashi
Publikováno v:
Nature. 615:900-906
Sex chromosome disorders severely compromise gametogenesis in both males and females. In oogenesis, the presence of an additional Y chromosome or the loss of an X chromosome disturbs the robust production of oocytes. Here we efficiently converted the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a1d828a664ffb3e9592ec74e410d31
https://doi.org/10.1038/s41586-023-05834-x
https://doi.org/10.1038/s41586-023-05834-x
Autor:
Atsuo Ogura, Tomoya S. Kitajima, Fumihiro Sugiyama, Hiroyuki Tateno, Seiya Mizuno, Tetsuo Kunieda, Kimiko Inoue, Yasuhiro Fujiwara, Yuki Osawa, Toshiaki Hino, Hirohisa Kyogoku, Narumi Ogonuki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::477cca4bdfe10f8f2f32f97eb54a6372
https://doi.org/10.15252/rc.2022495285
https://doi.org/10.15252/rc.2022495285
Autor:
Hiromitsu Araki, Chisako Horikawa, Kinichi Nakashima, Hirohisa Kyogoku, Katsuhiko Hayashi, Harry G. Leitch, Fumihito Miura, Orie Hikabe, Norio Hamada, So Shimamoto, Tomoya S. Kitajima, Takashi Ito, Nobuhiko Hamazaki
Publikováno v:
Nature. 589:264-269
During female germline development, oocytes become a highly specialized cell type and form a maternal cytoplasmic store of crucial factors. Oocyte growth is triggered at the transition from primordial to primary follicle and is accompanied by dynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4015232a7958d26deaa6a95b289107fa
https://doi.org/10.1038/s41586-020-3027-9
https://doi.org/10.1038/s41586-020-3027-9
Birth of mice from meiotically arrested spermatocytes following biparental meiosis in halved oocytes
Autor:
Narumi Ogonuki, Hirohisa Kyogoku, Toshiaki Hino, Yuki Osawa, Yasuhiro Fujiwara, Kimiko Inoue, Tetsuo Kunieda, Seiya Mizuno, Hiroyuki Tateno, Fumihiro Sugiyama, Tomoya S Kitajima, Atsuo Ogura
Publikováno v:
EMBO Rep
Microinjection of spermatozoa or spermatids into oocytes is a major choice for infertility treatment. However, the use of premeiotic spermatocytes has never been considered because of its technical problems. Here, we show that the efficiency of sperm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296e655253f8c98844ebce40e17f091a
https://europepmc.org/articles/PMC9253789/
https://europepmc.org/articles/PMC9253789/
Autor:
Fumihiro Sugiyama, Hirohisa Kyogoku, Kimiko Inoue, Atsuo Ogura, Hiroyuki Tateno, Tomoya S. Kitajima, Yuki Osawa, Seiya Mizuno, Narumi Ogonuki, Toshiaki Hino, Yasuhiro Fujiwara, Tetsuo Kunieda
While the large volume of mammalian oocytes is necessary for embryo development, it can lead to error-prone chromosomal segregation during meiosis. Conversely, we hypothesized that smaller oocytes would have a great unidentified potential to stabiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d13729493ceb70d2ec2424faf6d4e709
https://doi.org/10.1101/2021.09.03.458818
https://doi.org/10.1101/2021.09.03.458818