Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Tomoya O, Akama"'
Autor:
Keita Fujiwara, Tadashi Inoue, Aya Kimoto, Jiang Zixian, Keizo Tokuhiro, Yoshiki Yasukochi, Tomoya O. Akama, Chen-Leng Cai, Ichiro Shiojima, Hiroshi Kimura, Shige H. Yoshimura, Tomoyuki Nakamura, Maretoshi Hirai
Publikováno v:
Cell Reports, Vol 43, Iss 12, Pp 115048- (2024)
Summary: Cardiomyocyte (CM) nuclei are constantly exposed to mechanical stress, but how they maintain their nuclear shape remains unknown. In this study, we found that ventricular CM nuclei acquire characteristic prominent spatial organizations of he
Externí odkaz:
https://doaj.org/article/8ae6e71d01dd4681aaaba4f71d36cebc
Autor:
Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O. Akama, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura
Publikováno v:
Molecules, Vol 29, Iss 4, p 764 (2024)
We recently showed that 6-sulfo sialyl N-acetyllactosamine (LacNAc) in O-linked glycans recognized by the CL40 antibody is abundant in the pleural mesothelium under physiological conditions and that these glycans undergo complementary synthesis by Gl
Externí odkaz:
https://doaj.org/article/a05ca7c0095a482fa2f489acc5395c87
Autor:
Yoshiko Takeda-Uchimura, Kazuchika Nishitsuji, Midori Ikezaki, Tomoya O. Akama, Yoshito Ihara, Fabrice Allain, Kenji Uchimura
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Keratan sulfate (KS) glycan is covalently attached to a core protein of proteoglycans. KS is abundant in neuropils and presents densely in close proximity to the perineuronal region of the perineuronal net-positive neurons in the adult brain under ph
Externí odkaz:
https://doaj.org/article/214dfb5ce4f74815a00a5f1480ead8eb
Autor:
Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O. Akama, Kaho Nishioka, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura
Publikováno v:
Molecules, Vol 27, Iss 14, p 4543 (2022)
Sialyl 6-sulfo Lewis X (6-sulfo sLeX) and its derivative sialyl 6-sulfo N-acetyllactosamine (LacNAc) are sialylated and sulfated glycans of sialomucins found in the high endothelial venules (HEVs) of secondary lymphoid organs. A component of 6-sulfo
Externí odkaz:
https://doaj.org/article/dd9704c8613a46828188e078636ed947
Autor:
Motohiro Nonaka, Hideaki Mabashi-Asazuma, Donald L Jarvis, Kazuhiko Yamasaki, Tomoya O Akama, Masato Nagaoka, Toshio Sasai, Itsuko Kimura-Takagi, Yoichi Suwa, Takashi Yaegashi, Chun-Teng Huang, Chizuko Nishizawa-Harada, Michiko N Fukuda
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0241157 (2021)
We previously reported that IF7 peptide, which binds to the annexin A1 (ANXA1) N-terminus, functions as a tumor vasculature-targeted drug delivery vehicle after intravenous injection. To enhance IF7 stability in vivo, we undertook mirror-image peptid
Externí odkaz:
https://doaj.org/article/5d129291cb2948fdaf1c7fd0544d7567
Autor:
Terufumi Yoshida, Masaki Kaibori, Nanami Fujisawa, Mariko Ishizuka, Fusao Sumiyama, Masahiko Hatta, Hisashi Kosaka, Kosuke Matsui, Kensuke Suzuki, Tomoya O. Akama, Tayo Katano, Kengo Yoshii, Mitsuhiro Ebara, Mitsugu Sekimoto
Publikováno v:
Nanomaterials, Vol 12, Iss 8, p 1364 (2022)
Lenvatinib has a high response rate in unresectable advanced hepatocellular carcinoma (HCC). In this study, we investigated whether lenvatinib-incorporating poly(ε-caprolactone) sheets (lenvatinib sheets) as a drug delivery system (DDS) exerted anti
Externí odkaz:
https://doaj.org/article/5c3d49a85d07471eb4965295493582e2
Autor:
Yuzuru Ariga, Shulin Low, Hitomi Hoshino, Tsutomu Nakada, Tomoya O. Akama, Akifumi Muramoto, Mana Fukushima, Takahiro Yamauchi, Yusei Ohshima, Motohiro Kobayashi
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 70(10)
Spi-B, a member of the E26 transformation-specific (ETS) family of transcription factors, plays an important role in B cell differentiation. Spi-B also functions in development of diffuse large B-cell lymphoma; thus, we hypothesized that it may parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d12fd98b6cc24634307fa9c1f85b42
https://pubmed.ncbi.nlm.nih.gov/36169277
https://pubmed.ncbi.nlm.nih.gov/36169277
Autor:
Mana Fukushima, Akiya Kogami, Tomoya O. Akama, Tadakazu Okoshi, Haruo Ohtani, Junya Mitoma, Takuya Komeno, Motohiro Kobayashi, Hitomi Hoshino, Masataka Murahashi
Publikováno v:
J Histochem Cytochem
Angioimmunoblastic T-cell lymphoma (AITL) is a T-cell lymphoma of follicular helper T-cell origin. Histologically, neoplastic T-cells proliferate to form clusters adjacent to or between arborizing high endothelial venules (HEVs). HEVs in normal lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cae6c33d92abb912e17d576189de7fb
https://doi.org/10.1369/00221554211048551
https://doi.org/10.1369/00221554211048551
Autor:
Chun-Teng Huang, Minoru Fukuda, Yoichi Suwa, Toshio Sasai, Motohiro Nonaka, Michiko N. Fukuda, Kazuhiro Sugihara, Tomoya O. Akama, Kazuhiko Yamasaki, Jun Nakayama, Itsuko Kimura-Takagi, Takashi Yaegashi, Jiunn Chern Yeh, Hideaki Mabashi-Asazuma, Chizuko Nishizawa-Harada, Alexandre Rosa Campos, Misa Suzuki-Anekoji, Toshiaki K. Shibata, Masato Nagaoka, Donald L. Jarvis
Publikováno v:
British Journal of Cancer
Background Annexin A1 is expressed specifically on the tumour vasculature surface. Intravenously injected IF7 targets tumour vasculature via annexin A1. We tested the hypothesis that IF7 overcomes the blood–brain barrier and that the intravenously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74615f6b64e73fceabf514e8e359b9f
https://doi.org/10.1038/s41416-020-01066-2
https://doi.org/10.1038/s41416-020-01066-2
Autor:
Masataka Murahashi, Akiya Kogami, Akifumi Muramoto, Hitomi Hoshino, Tomoya O. Akama, Junya Mitoma, Takanori Goi, Atsuhiro Hirayama, Takuma Okamura, Tadanobu Nagaya, Motohiro Kobayashi
Publikováno v:
J Histochem Cytochem
It is widely accepted that E-selectin, an inducible endothelial cell adhesion molecule, plays a critical role in the initial step of neutrophil recruitment to sites of acute inflammation. However, immunohistological analysis of E-selectin has been ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b43a805dc856be19282eee15446cf1
https://europepmc.org/articles/PMC8971687/
https://europepmc.org/articles/PMC8971687/
