Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tomoya Kuji"'
Autor:
Hikaru Nozawa, Fritz Nagae, Satoshi Ogihara, Rina Hirano, Hirohito Yamazaki, Ryo Iizuka, Munetaka Akatsu, Tomoya Kujirai, Shoji Takada, Hitoshi Kurumizaka, Sotaro Uemura
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract The nucleosome including H2A.B, a mammalian-specific H2A variant, plays pivotal roles in spermatogenesis, embryogenesis, and oncogenesis, indicating unique involvement in transcriptional regulation distinct from canonical H2A nucleosomes. De
Externí odkaz:
https://doaj.org/article/3410c6932f6c40faa76ba1e820d6c511
Autor:
Akiko Fujimura, Hisashi Ishida, Tamiko Nozaki, Shuhei Terada, Yuto Azumaya, Tadashi Ishiguro, Yugo R. Kamimura, Tomoya Kujirai, Hitoshi Kurumizaka, Hidetoshi Kono, Kenzo Yamatsugu, Shigehiro A. Kawashima, Motomu Kanai
Publikováno v:
ACS Central Science, Vol 9, Iss 11, Pp 2115-2128 (2023)
Externí odkaz:
https://doaj.org/article/b35bf482716e4c2ab9429ea65fa36663
Autor:
Naohiro Kuwayama, Tomoya Kujirai, Yusuke Kishi, Rina Hirano, Kenta Echigoya, Lingyan Fang, Sugiko Watanabe, Mitsuyoshi Nakao, Yutaka Suzuki, Kei-ichiro Ishiguro, Hitoshi Kurumizaka, Yukiko Gotoh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Identification of factors that regulate chromatin condensation is important for understanding of gene regulation. High-mobility group AT-hook (HMGA) proteins 1 and 2 are abundant nonhistone chromatin proteins that play a role in many biologi
Externí odkaz:
https://doaj.org/article/7f8d3463872a484badc42ef07230b985
Autor:
Misuzu Habazaki, Shinsuke Mizumoto, Hidetoshi Kajino, Tomoya Kujirai, Hitoshi Kurumizaka, Shigehiro A. Kawashima, Kenzo Yamatsugu, Motomu Kanai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Life emerges from a network of biomolecules and chemical reactions catalyzed by enzymes. As enzyme abnormalities are often connected to various diseases, a chemical catalyst promoting physiologically important intracellular reactions in plac
Externí odkaz:
https://doaj.org/article/8156d1d6d4ed4143bdbccaca68aeba30
Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1
Autor:
Rina Hirano, Haruhiko Ehara, Tomoya Kujirai, Tamami Uejima, Yoshimasa Takizawa, Shun-ichi Sekine, Hitoshi Kurumizaka
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The mechanism by which RNAPII transcribes the DNA in the chromatosome with H1 has remained enigmatic. Here the authors present the cryo-EM structures of the RNAPII-chromatosome complexes, and explain how RNAPII is regulated by H1 in chromatin.
Externí odkaz:
https://doaj.org/article/5e9682fe85694f7a96b35df8cc360283
Publikováno v:
Materials Sciences and Applications. :911-916
Several drawing processes of 3N pure copper (Cu) with ultra high reduction in area have been performed, and the texture has been observed using electron back scattered diffraction. It is well known that the texture of drawn Cu is closely related to i
Publikováno v:
Cells, Vol 12, Iss 10, p 1388 (2023)
In eukaryotes, genomic DNA is tightly wrapped in chromatin. The nucleosome is a basic unit of chromatin, but acts as a barrier to transcription. To overcome this impediment, the RNA polymerase II elongation complex disassembles the nucleosome during
Externí odkaz:
https://doaj.org/article/721bb27f5fdc436bb19f7346e99b5432
Autor:
Rina Hirano, Yasuhiro Arimura, Tomoya Kujirai, Mikihiro Shibata, Aya Okuda, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Hitoshi Kurumizaka
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Hirano et al. show that the H2A.B-H2B histone dimer incorporated within the nucleosome exchanges with the canonical H2A-H2B dimer without assistance from histone chaperones or nucleosome remodelers. This study provides insights into how the H2A.B nuc
Externí odkaz:
https://doaj.org/article/e5db19da91414c99b864481c4f745c6e
Publikováno v:
MRS Proceedings. 980
To design and to develop Half-Heusler based high-temperature thermoelectric materials, thermoelectric properties of n-type MNiSn and p-type MPtSn (M = Hf, Zr) were investigated based on two respective strategies. For the n-type (Hf, Zr)NiSn, a combin
Publikováno v:
MRS Proceedings. 886
We have succeeded to grow almost single-phase of Half-Heusler intermetallic compounds MNiSn, where M = (Hfx,Zr1−x) and x varies from 0 to 1, for the first time by directional solidification using optical floating zone melting (OFZ). Thermoelectric