Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Tomoya Kono"'
Autor:
Yo Okamura, Hiroshi Miyanishi, Masato Kinoshita, Tomoya Kono, Masahiro Sakai, Jun-ichi Hikima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract In the intestine, the host must be able to control the gut microbiota and efficiently absorb transiently supplied metabolites, at the risk of enormous infection. In mammals, the inflammatory cytokine interleukin (IL)-17A/F is one of the key
Externí odkaz:
https://doaj.org/article/e352f1cbbb6345aaa7428dfeb60b8e2e
Publikováno v:
Fish and Shellfish Immunology Reports, Vol 2, Iss , Pp 100028- (2021)
Phospholipase A2 (PLA2), a phospholipid hydrolase, has recently attracted attention owing to its broad functionality. Immunological evidence has revealed increased susceptibility to infectious diseases and immunodeficiency in knockout (KO) mice of se
Externí odkaz:
https://doaj.org/article/ac4779681a394bd185cd712d1df3fe13
Autor:
Yoshie Takahashi, Yo Okamura, Nanaki Harada, Mika Watanabe, Hiroshi Miyanishi, Tomoya Kono, Masahiro Sakai, Jun-ichi Hikima
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mucosal tissue forms the first line of defense against pathogenic microorganisms. Cellular damage in the mucosal epithelium may induce the interleukin (IL)-22-related activation of many immune cells, which are essential for maintaining the mucosal ep
Externí odkaz:
https://doaj.org/article/7eaaf3cc3c2c4beda861f2470749437f
Autor:
Yo Okamura, Natsuki Morimoto, Daisuke Ikeda, Nanami Mizusawa, Shugo Watabe, Hiroshi Miyanishi, Yuichi Saeki, Haruko Takeyama, Takashi Aoki, Masato Kinoshita, Tomoya Kono, Masahiro Sakai, Jun-ichi Hikima
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In mammals, interleukin (IL)-17A and F are hallmark inflammatory cytokines that play key roles in protection against infection and intestinal mucosal immunity. In the gastrointestinal tract (GI), the induction of antimicrobial peptide (AMP) productio
Externí odkaz:
https://doaj.org/article/c510216ac3734419b82af9f6a7bb9140
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4389 (2021)
Pattern recognition receptors (PRRs) play a crucial role in inducing inflammatory responses; they recognize pathogen-associated molecular patterns, damage-associated molecular patterns, and environmental factors. Nucleotide-binding oligomerization do
Externí odkaz:
https://doaj.org/article/61b493ff58fb414688250459e259c21a
Autor:
Tomonori Nakanishi, Mayuko Anraku, Ryoji Suzuki, Tomoya Kono, Laurie Erickson, Satoshi Kawahara
Publikováno v:
Journal of Functional Foods, Vol 21, Iss , Pp 283-289 (2016)
Phytanic acid is one of the constituents of animal products with possible health benefits through improving lipid and glucose metabolism; however, its immunomodulatory effects remain undetermined. The in vitro effects of phytanic acid and its related
Externí odkaz:
https://doaj.org/article/2c6b058dfd644ffa92e298b749e4b0bb
Autor:
Meiko Takahashi, Takanobu Yoshimoto, Masayuki Shimoda, Tomoya Kono, Masayuki Koizumi, Shujiro Yazumi, Yutaka Shimada, Ryuichiro Doi, Tsutomu Chiba, Hajime Kubo
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 12, Pp 1003-1010 (2006)
The importance of genetic mutations in carcinogenesis has been recognized, and it has been proposed that aberrant mutation of mRNA may represent a novel oncogenic principle. Here we report that the mRNA of a homeobox gene prox1, a candidate tumor sup
Externí odkaz:
https://doaj.org/article/32d524db1af6437bb951faffa582c8f8
Autor:
Tomoya Kono, Hiroki Korenaga
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66364 (2013)
CD4(+) T (Th) cells are a central component of the adaptive immune response and are divided into distinct sets based on their specific cytokine production pattern. Several reports have suggested that fish possess Th subset activity similar to that of
Externí odkaz:
https://doaj.org/article/402b6a0245634a41abb1c7b11f757a98
Autor:
Tomoya Kono
Publikováno v:
Asian Fisheries Science, Vol 23, Iss 4 (2011)
Externí odkaz:
https://doaj.org/article/5b5762f51cca45c590853bb9f986583c
Autor:
Tomoya, Takeuchi, Takahiko, Hata, Hiroshi, Miyanishi, Takumi, Yuasa, Suzuka, Setoguchi, Ayaka, Takeda, Natsuki, Morimoto, Jun-Ichi, Hikima, Masahiro, Sakai, Tomoya, Kono
Publikováno v:
Fish & Shellfish Immunology. 127:238-246
In recent years, studies on circadian control in immunity have been actively conducted in mammals, but little is known about circadian rhythms in the field of fish immunology. In this study, we aimed to analyse the regulation of the diel oscillation