Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Tomoya Isaji"'
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87938 (2014)
MicroRNA 130b (miR-130b) is significantly dysregulated in various human tumor types. In this study, using a microarray assay, we characterized the upregulation of miR-130b expression in colorectal cancer (CRC) specimens. However, there is limited kno
Externí odkaz:
https://doaj.org/article/607929601de648a582c058e0ebe9e3f2
Autor:
Tomoya Isaji, Jianguo Gu
Publikováno v:
Trends in Glycoscience and Glycotechnology. 34:E91-E95
Autor:
Yuhan Sun1, Tomoya Isaji1 isaji@tohoku-mpu.ac.jp, Yoshiyuki Oyama1, Xing Xu1, Jianwei Liu1, Hisatoshi Hanamatsu2, Ikuko Yokota3, Nobuaki Miura4, Jun-ichi Furukawa2,3, Tomohiko Fukuda1, Jianguo Gu1 jgu@tohoku-mpu.ac.jp
Publikováno v:
Journal of Biological Chemistry. Aug2023, Vol. 299 Issue 8, p1-14. 14p.
Autor:
Wanli Song, Caixia Liang, Yuhan Sun, Sayaka Morii, Shin Yomogida, Tomoya Isaji, Tomohiko Fukuda, Qinglei Hang, Akiyoshi Hara, Miyako Nakano, Jianguo Gu
Publikováno v:
Journal of Biological Chemistry. 299:103051
Publikováno v:
Biochemical and Biophysical Research Communications. 523:226-232
The N-glycosylation of integrin α5β1 is involved in multiple cell biological functions. Our group previously reported that the N-glycosylation of the Calf-1,2 domain on α5 subunit (S3-5,10-14) was important for its inhibitory effect on EGFR signal
Publikováno v:
The FASEB Journal. 34:881-897
The α2,3-sialylation of N-glycans is considered important but complicated because the functions of the three β-galactoside α2,3-sialyltransferases, ST3GAL3, ST3GAL4, and ST3GAL6, could be compensating for one another. To distinguish their specific
Publikováno v:
Journal of Biological Chemistry. 294:4425-4436
Aberrant N-glycan sialylation of glycoproteins is closely associated with malignant phenotypes of cancer cells and metastatic potential, which includes cell adhesion, migration, and growth. Recently, phosphatidylinositol 4-kinase IIα (PI4KIIα), whi
Autor:
Tomoya Isaji, Wanli Song, Chengwei Duan, Yuqin Wang, Caixia Liang, Tomohiko Fukuda, Jianguo Gu
Publikováno v:
Biochimica et biophysica acta. General subjects. 1865(6)
Background Pancreatic carcinoma is one of the deadliest malignant diseases, in which the increased expression of α1,6-fucosyltransferase (FUT8), a sole enzyme responsible for catalyzing core fucosylation, has been reported. However, its pathological
Publikováno v:
Biochemical and biophysical research communications. 522(4)
The epithelial cell adhesion molecule (EpCAM) is one of the most frequently and intensely expressed of tumor-associated antigens, but the role that EpCAM plays in the proliferation, adhesion and migration properties of cancer cells remains unclear. I
Autor:
Jianguo Gu, Tomohiko Fukuda, Feng Qi, Chengwei Duan, Shinichiro Takahashi, Yuqin Wang, Jie Yang, Tomoya Isaji
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(2)
Fms-like tyrosine kinase 3 (FLT3) is a glycoprotein, that is a member of the class III receptor tyrosine kinase family. Approximately one-third of acute myeloid leukemia (AML) patients have mutations of this gene, and activation of the FLT3 downstrea