Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Tomoya Hino"'
Publikováno v:
Biophysics and Physicobiology, Vol 19 (2022)
Steroid hormones modulate numerous physiological processes in various higher organisms. Research on the physiology, biosynthesis, and metabolic degradation of steroid hormones is crucial for developing drugs, agrochemicals, and anthelmintics. Most st
Externí odkaz:
https://doaj.org/article/37273e9c4ce24ddaa7b867225345213d
Autor:
Alexander M. Wolff, Iris D. Young, Raymond G. Sierra, Aaron S. Brewster, Michael W. Martynowycz, Eriko Nango, Michihiro Sugahara, Takanori Nakane, Kazutaka Ito, Andrew Aquila, Asmit Bhowmick, Justin T. Biel, Sergio Carbajo, Aina E. Cohen, Saul Cortez, Ana Gonzalez, Tomoya Hino, Dohyun Im, Jake D. Koralek, Minoru Kubo, Tomas S. Lazarou, Takashi Nomura, Shigeki Owada, Avi J. Samelson, Tomoyuki Tanaka, Rie Tanaka, Erin M. Thompson, Henry van den Bedem, Rahel A. Woldeyes, Fumiaki Yumoto, Wei Zhao, Kensuke Tono, Sebastien Boutet, So Iwata, Tamir Gonen, Nicholas K. Sauter, James S. Fraser, Michael C. Thompson
Publikováno v:
IUCrJ, Vol 7, Iss 2, Pp 306-323 (2020)
Innovative new crystallographic methods are facilitating structural studies from ever smaller crystals of biological macromolecules. In particular, serial X-ray crystallography and microcrystal electron diffraction (MicroED) have emerged as useful me
Externí odkaz:
https://doaj.org/article/6e6b471c98104285badfe50aab472279
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 8, p e1002674 (2012)
Nitric oxide reductases (NORs) are membrane proteins that catalyze the reduction of nitric oxide (NO) to nitrous oxide (N(2)O), which is a critical step of the nitrate respiration process in denitrifying bacteria. Using the recently determined first
Externí odkaz:
https://doaj.org/article/947add0f42fc44cc9d356b2ff5f3c8f2
Publikováno v:
Biochemical and Biophysical Research Communications. 596:43-48
ε-poly-l-lysine (ε-PL) synthetase (Pls) is a membrane protein that possesses both adenylation and thiolation domains, characteristic of non-ribosomal peptide synthetases (NRPSs). Pls catalyzes the polymerization of l-Lys molecules in a highly speci
Autor:
Tesshin, Uegaki, Taisei, Takei, Shuhei, Yamaguchi, Keisuke, Fujiyama, Yusuke, Sato, Tomoya, Hino, Shingo, Nagano
Publikováno v:
International journal of molecular sciences. 24(1)
Ladderane lipids (found in the membranes of anaerobic ammonium-oxidizing [anammox] bacteria) have unique ladder-like hydrophobic groups, and their highly strained exotic structure has attracted the attention of scientists. Although enzymes encoded in
Autor:
Hiroyuki Osada, Yuji Sugita, Keisuke Fujiyama, Toshihiko Nogawa, Kiyomi Kinugasa, Suyong Re, Shunji Takahashi, Shingo Nagano, Kohei Watanabe, Tomoya Hino, Naoki Kato, Ryo Takita
Publikováno v:
Angewandte Chemie (International Ed. in English)
Enzymes catalyzing [4+2] cycloaddition have attracted increasing attention because of their key roles in natural product biosynthesis. Here, we solved the X‐ray crystal structures of a pair of decalin synthases, Fsa2 and Phm7, that catalyze intramo
Autor:
Alexander M. Wolff, Eriko Nango, Iris D. Young, Aaron S. Brewster, Minoru Kubo, Takashi Nomura, Michihiro Sugahara, Shigeki Owada, Benjamin A. Barad, Kazutaka Ito, Asmit Bhowmick, Sergio Carbajo, Tomoya Hino, James M. Holton, Dohyun Im, Lee J. O’Riordan, Tomoyuki Tanaka, Rie Tanaka, Raymond G. Sierra, Fumiaki Yumoto, Kensuke Tono, So Iwata, Nicholas K. Sauter, James S. Fraser, Michael C. Thompson
Understanding and controlling protein motion at atomic resolution is a hallmark challenge for structural biologists and protein engineers because conformational dynamics are essential for complex functions such as enzyme catalysis and allosteric regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::698d152d45b8f079d9f639fc74329611
https://doi.org/10.1101/2022.06.10.495662
https://doi.org/10.1101/2022.06.10.495662
Autor:
Ryoji, Suno, Yukihiko, Sugita, Kazushi, Morimoto, Hiroko, Takazaki, Hirokazu, Tsujimoto, Mika, Hirose, Chiyo, Suno-Ikeda, Norimichi, Nomura, Tomoya, Hino, Asuka, Inoue, Kenji, Iwasaki, Takayuki, Kato, So, Iwata, Takuya, Kobayashi
Publikováno v:
Cell reports. 40(11)
Prostaglandin receptors have been implicated in a wide range of functions, including inflammation, immune response, reproduction, and cancer. Our group has previously determined the crystal structure of the active-like EP3 bound to its endogenous ago
Publikováno v:
Biophys J
The membrane-embedded protein rhodopsin is widely produced in organisms as a photoreceptor showing a variety of light-dependent biological functions. To investigate its molecular features, rhodopsin is often extracted from cellular membrane lipids by
Autor:
Kazuki Nishimoto, Takayuki Motoyama, Naoshi Dohmae, Choong-Soo Yun, Shingo Nagano, Tomoya Hino, Hiroyuki Osada, Takeshi Shimizu
Publikováno v:
J Biol Chem
Many microbial secondary metabolites are produced by multienzyme complexes comprising nonribosomal peptide synthetases (NRPSs) and polyketide synthases (PKSs). The ketosynthase (KS) domains of polyketide synthase normally catalyze the decarboxylative