Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Tomoya Hikita"'
Autor:
Fumie Mitani, Jianyu Lin, Tatsuya Sakamoto, Ryo Uehara, Tomoya Hikita, Takuya Yoshida, Andi Setiawan, Masayoshi Arai, Chitose Oneyama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cancer cells secrete aberrantly large amounts of extracellular vesicles (EVs) including exosomes, which originate from multivesicular bodies (MVBs). Because EVs potentially contribute to tumor progression, EV inhibitors are of interest as no
Externí odkaz:
https://doaj.org/article/1a6636c7420f4abbb5b55c3f044c96a4
Autor:
Shin Morioka, Hiroki Nakanishi, Toshiyoshi Yamamoto, Junya Hasegawa, Emi Tokuda, Tomoya Hikita, Tomoko Sakihara, Yuuki Kugii, Chitose Oneyama, Masakazu Yamazaki, Akira Suzuki, Junko Sasaki, Takehiko Sasaki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Different phosphoinositide isomers are involved in a variety of physiological and pathological processes. Here, the authors combine chiral column chromatography and mass spectrometry to measure phosphoinositide regioisomers, revealing their dynamic c
Externí odkaz:
https://doaj.org/article/86945ee841384d22b480e5b663720b37
Autor:
Ryosuke Hayasaka, Sho Tabata, Masako Hasebe, Satsuki Ikeda, Tomoya Hikita, Chitose Oneyama, Jun Yoshitake, Daisuke Onoshima, Kumiko Takahashi, Takahiro Shibata, Koji Uchida, Yoshinobu Baba, Tomoyoshi Soga, Masaru Tomita, Akiyoshi Hirayama
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Cancer-derived small extracellular vesicles (sEVs) are multifunctional particles with a lipid bilayer structure that are involved in cancer progression, such as malignant proliferation, distant metastasis, and cancer immunity evasion. The separation
Externí odkaz:
https://doaj.org/article/ae8ad54e7a964820a6d9d622d040ef46
Autor:
Akira Minami, Masakazu Saito, Shou Mamada, Daisuke Ieno, Tomoya Hikita, Tadanobu Takahashi, Tadamune Otsubo, Kiyoshi Ikeda, Takashi Suzuki
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165257 (2016)
Sialic acid bound to glycans in glycolipids and glycoproteins is essential for synaptic plasticity and memory. Sialidase (EC 3.2.1.18), which has 4 isozymes including Neu1, Neu2, Neu3 and Neu4, regulates the sialylation level of glycans by removing s
Externí odkaz:
https://doaj.org/article/80ba01b87e7e45af84500593689ab8c1
Autor:
Tomoya Hikita, Ryo Uehara, Reina E. Itoh, Fumie Mitani, Mamiko Miyata, Takuya Yoshida, Rui Yamaguchi, Chitose Oneyama
Publikováno v:
Cancer Science. 113:1264-1276
Cancer cells secrete large amounts of extracellular vesicles (EVs) originating from multivesicular bodies (MVBs). Mature MVBs fuse either with the plasma membrane for release as EVs, often referred as to exosomes or with lysosomes for degradation. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2925127c495dc597fab45352f391892b
https://doi.org/10.1111/cas.15288
https://doi.org/10.1111/cas.15288
Autor:
Tomoya Hikita, Masaomi Kimura
Publikováno v:
Advances in Intelligent Systems and Computing ISBN: 9783031148583
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c12b6cb8512f577a31216b95345c021
https://doi.org/10.1007/978-3-031-14859-0_4
https://doi.org/10.1007/978-3-031-14859-0_4
Autor:
Tomoya, Hikita, Chitose, Oneyama
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2524
Bioluminescence (BL) has been widely used to quantitatively monitor various biological phenomena. Here, we describe a protocol for preparing and using cells expressing exosomes labeled with luciferase. The BL of the culture medium of these cells is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a027da982287130f52b0ff9742827521
https://pubmed.ncbi.nlm.nih.gov/35821479
https://pubmed.ncbi.nlm.nih.gov/35821479
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Monitoring of exosome dynamics in living organisms is essential to demonstrate the real functions of cancer-derived exosomes. Currently, these have been elucidated in vitro or under non-physiological conditions in vivo in most cases. To overcome thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d327d5644847848be468e7ebf2f28388
http://link.springer.com/article/10.1038/s41598-020-73580-5
http://link.springer.com/article/10.1038/s41598-020-73580-5
Autor:
Tomoya Hikita, Chitose Oneyama
Publikováno v:
Bioluminescence ISBN: 9781071624524
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c40df59480115b9c8c94d8779014cd1f
https://doi.org/10.1007/978-1-0716-2453-1_21
https://doi.org/10.1007/978-1-0716-2453-1_21
Autor:
Masashi Sanada, Mika Takai, Satoko Shimada, Eisuke Iwamoto, Fumihiko Hayakawa, Akihiko Sakamoto, Tomoya Hikita, Kazuyuki Shimada, Shunsuke Kunou, Tomohiro Aoki, Hitoshi Kiyoi, Yusuke Kagaya, Chitose Oneyama
Publikováno v:
Oncogene
The tumor microenvironment is deeply involved in the process of tumor growth and development. In this study, we focused on cancer-associated fibroblasts (CAFs) and their derived exosomes on the lymphoma microenvironment to uncover their clinical sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b37c1da24f2827504d5130da32dd5af
https://pubmed.ncbi.nlm.nih.gov/33994542
https://pubmed.ncbi.nlm.nih.gov/33994542