Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tomotaka OKAMURA"'
Autor:
Chieko Yokota, Kosuke Fujimoto, Natsuko Yamakawa, Masamitsu Kono, Daichi Miyaoka, Masaki Shimohigoshi, Miho Uematsu, Miki Watanabe, Yukari Kamei, Akira Sugimoto, Natsuko Kawasaki, Takato Yabuno, Tomotaka Okamura, Eisuke Kuroda, Shigeto Hamaguchi, Shintaro Sato, Muneki Hotomi, Yukihiro Akeda, Ken J. Ishii, Yasuhiro Yasutomi, Kishiko Sunami, Satoshi Uematsu
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-12 (2023)
Abstract Background Although vaccination is recommended for protection against invasive pneumococcal disease, the frequency of pneumococcal pneumonia is still high worldwide. In fact, no vaccines are effective for all pneumococcal serotypes. Fusion p
Externí odkaz:
https://doaj.org/article/707122d771834299ab42a5fa158c5832
Autor:
Tomotaka Okamura, Yuya Shimizu, Masamitsu N. Asaka, Tomohiro Kanuma, Yusuke Tsujimura, Takuya Yamamoto, Kazuhiro Matsuo, Yasuhiro Yasutomi
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-18 (2021)
Abstract The use of an adjuvant in vaccination is thought to be effective for enhancing immune responses to various pathogens. We genetically constructed a live attenuated simian human immunodeficiency virus (SHIV) to express the adjuvant molecule Ag
Externí odkaz:
https://doaj.org/article/31b33892f7494441b84085b8894ee5c9
Autor:
Maya Shofa, Tomotaka Okamura, Emiko Urano, Yoshiharu Matsuura, Yasuhiro Yasutomi, Akatsuki Saito
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14002 (2022)
Zika virus (ZIKV) outbreaks in Central and South America caused severe public health problems in 2015 and 2016. These outbreaks were finally contained through several methods, including mosquito control using insecticides and repellents. Additionally
Externí odkaz:
https://doaj.org/article/ba943c1211c341cc80aac00e5a5961b5
Autor:
Motomu Nakatake, Hajime Kurosaki, Nozomi Kuwano, Kosuke Horita, Mai Ito, Hiromichi Kono, Tomotaka Okamura, Kosei Hasegawa, Yasuhiro Yasutomi, Takafumi Nakamura
Publikováno v:
Molecular Therapy: Oncolytics, Vol 14, Iss , Pp 159-171 (2019)
Vaccinia virus (VV) has been utilized in oncolytic virotherapy, but it risks a host antiviral immune response. VV has an extracellular enveloped virus (EEV) form consisting of a normal virion covered with a host-derived outer membrane that enables it
Externí odkaz:
https://doaj.org/article/62edb807eaa94f1ca4186d396229d2e9
Autor:
Emiko Urano, Yumi Itoh, Tatsuya Suzuki, Takanori Sasaki, Jun-ichi Kishikawa, Kanako Akamatsu, Yusuke Higuchi, Yusuke Sakai, Tomotaka Okamura, Shuya Mitoma, Fuminori Sugihara, Akira Takada, Mari Kimura, Mika Hirose, Tadahiro Sasaki, Ritsuko Koketsu, Shunya Tsuji, Shota Yanagida, Tatsuo Shioda, Eiji Hara, Satoaki Matoba, Yoshiharu Matsuura, Yasunari Kanda, Hisashi Arase, Masato Okada, Junichi Takagi, Takayuki Kato, Atsushi Hoshino, Yasuhiro Yasutomi, Akatsuki Saito, Toru Okamoto
The Omicron variant continuously evolves under the humoral immune pressure obtained by vaccination and SARS-CoV-2 infection and the resultant Omicron subvariants exhibit further immune evasion and antibody escape. Engineered ACE2 decoy composed of hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9428d3d93df375c7414efd4a7d7d1d94
https://doi.org/10.1101/2022.12.29.522275
https://doi.org/10.1101/2022.12.29.522275
Autor:
Shiho FUJITA, Tadashi SANKAI, Shouji KAWAMURA, Kazunori YAMADA, Iori ITAGAKI, Hideki SUGIURA, Yoshiki MORIMITSU, Shinichi HAYAMA, Tetsuya SAKAMAKI, Masayuki TANAKA, Tomotaka OKAMURA, Hideshi TSUSAKI
Publikováno v:
Primate Research. 37:177-182
Autor:
Emiko Urano, Kayoko Ueda, Mahoko Higuchi, Mugi Furukawa, Tomotaka Okamura, Yuetsu Tanaka, Yasuhiro Yasutomi
Publikováno v:
Journal of Virology. 96
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However, the precise mechanisms leading to HTLV-1 chronic infection and the ons
Publikováno v:
Translational and Regulatory Sciences. 4:20-24
Autor:
Aftab A. Ansari, Hirotaka Sato, Emi E. Nakayama, Francois Villinger, Yohei Saito, Nursarat Ahmed, Tatsuo Shioda, Tomotaka Okamura, Kazuyasu Mori, Masayuki Fujino, Chie Sugimoto, Kouji Matsushima, Ken-Ichi Hanaki, Satoru Watanabe
Publikováno v:
The Journal of Immunology. 205:1331-1344
Deglycosylated, live-attenuated SIV vaccines elicited protective immune responses against heterologous SIVsmE543-3, which differs from the vaccine strain SIVmac239 to levels similar to those across HIV-1 clades. Two thirds of the vaccinees contained
Autor:
Satoshi Nagata, Wataru Kamitani, Tomotaka Okamura, Shiori Ueno, Mahoko Higuchi, Yoshiharu Matsuura, Yasuhiro Yasutomi, Yoshihiro Kawaoka, Haruhiko Kamada, Emiko Urano, Chikako Ono, Mugi Furukawa
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance COVID-19 has shown severe pathogenicity in people with underlying diseases and in elderly people. It is necessary to elucidate the pathological conditions in patients with underlying diseases and in elderly patients. The use of appropria