Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tomoshi, Kakeya"'
Autor:
Harutsugu Tatebe, Takashi Kasai, Takuma Ohmichi, Yusuke Kishi, Tomoshi Kakeya, Masaaki Waragai, Masaki Kondo, David Allsop, Takahiko Tokuda
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-11 (2017)
Abstract Background There is still a substantial unmet need for less invasive and lower-cost blood-based biomarkers to detect brain Alzheimer’s disease (AD) pathology. This study is aimed to determine whether quantification of plasma tau phosphoryl
Externí odkaz:
https://doaj.org/article/769b90d66b04440387e11f8bc344dec7
Autor:
Takuma Ohmichi, Takashi Kasai, Masaki Kondo, Harutsugu Tatebe, Takahiko Tokuda, David Allsop, Masaaki Waragai, Tomoshi Kakeya, Yusuke Kishi
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-11 (2017)
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-11 (2017)
Background There is still a substantial unmet need for less invasive and lower-cost blood-based biomarkers to detect brain Alzheimer’s disease (AD) pathology. This study is aimed to determine whether quantification of plasma tau phosphorylated at t
Autor:
Tomoshi Kakeya, Ayako Sakai, Ken-ichi Tanamoto, Jun-ichi Sawada, Yutaka Kikuchi, Kosuke Takatori, Takeshi Yamazaki, Osamu Nakajima, Naoto Yamaguchi, Haruo Matsuda, Kikuko Ikeda
Publikováno v:
FEBS Journal. 275:2965-2976
The human prion protein (PrP) is a glycoprotein with a glycosylphosphatidylinositol (GPI) anchor at its C-terminus. Here we report alternative splicing within exon 2 of the PrP gene (PRNP) in the human glioblastoma cell line T98G. The open reading fr
Autor:
Norimasa Tamehiro, Tomoshi Kakeya, Kazuhiro Suzuki, Taku Nagao, Ryuichiro Sato, Yukari Shigemoto-Mogami, Tomoko Nishimaki-Mogami, Keiichiro Okuhira
Publikováno v:
Journal of Biological Chemistry. 282:21090-21099
ABC transporter A1 (ABCA1) mediates and rate-limits biogenesis of high density lipoprotein (HDL), and hepatic ABCA1 plays a major role in regulating plasma HDL levels. HDL generation is also responsible for release of cellular cholesterol. In periphe
Autor:
Jun-ichi Sawada, Takeshi Yamazaki, Yutaka Kikuchi, Ken-ichi Tanamoto, Ayako Sakai, Tomoshi Kakeya, Kosuke Takatori, Haruo Matsuda, Naoto Nakamura
Publikováno v:
Journal of General Virology. 85:3449-3457
Human prion diseases, such as Creutzfeldt–Jakob disease (CJD), a lethal, neurodegenerative condition, occur in sporadic, genetic and transmitted forms. CJD is associated with the conversion of normal cellular prion protein (PrPC) into a protease-re
Autor:
Ryusei Matsumura, Sakae Takeuchi, Tomoshi Kakeya, Chika Takagi, Kiyoshi Okuda, Sumio Takahashi
Publikováno v:
Neuroendocrinology. 78:96-104
The intermediate lobe of rodent pituitaries is involved in the regulation of prolactin (PRL) secretion from the anterior lobe. In a previous study, we demonstrated the stimulatory effect of alpha-melanocyte-stimulating hormone (alpha-MSH) on PRL rele
Publikováno v:
Zoological Science. 19(7):789-795
Several reports have indicated that prolactin-secreting cells (PRL cells) are generated from growth hormone-secreting cells (GH cells). We have shown that treatment with a combination of epidermal growth factor (EGF), insulin, and estradiol-17beta (E
Autor:
Jun-ichi Sawada, Morikazu Shinagawa, Takeshi Yamazaki, Ken-ichi Tanamoto, Motohiro Horiuchi, Yutaka Kikuchi, Akio Tanimura, Kosuke Takatori, Tomoshi Kakeya, Kaori Takekida
Publikováno v:
Journal of Health Science. 48:288-291
Transmissible spongiform encephalopathy (TSE) is a neurodegenerative disease characterized by spongiform degeneration and accumulation of an infectious isoform (PrPSc) of the prion protein in the central nervous system. PrPSc originates from a ubiqui
Publikováno v:
Cell and Tissue Research. 299:237-243
Autor:
Yutaka, Kikuchi, Tomoshi, Kakeya, Osamu, Nakajima, Ayako, Sakai, Kikuko, Ikeda, Naoto, Yamaguchi, Takeshi, Yamazaki, Ken-ichi, Tanamoto, Haruo, Matsuda, Jun-ichi, Sawada, Kosuke, Takatori
Publikováno v:
The FEBS journal. 275(11)
The human prion protein (PrP) is a glycoprotein with a glycosylphosphatidylinositol (GPI) anchor at its C-terminus. Here we report alternative splicing within exon 2 of the PrP gene (PRNP) in the human glioblastoma cell line T98G. The open reading fr