Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Tomonori Tsukahara"'
Autor:
Keiya Ozawa, Akihiro Kume, Hiroaki Mizukami, Masashi Urabe, Yasushi Saga, Hiroyuki Mizuguchi, Tomonori Tsukahara, Ryosuke Uchibori
PDF file - 104K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092865d9fbf68b1b717a3ae384ce6c3a
https://doi.org/10.1158/0008-5472.22394117
https://doi.org/10.1158/0008-5472.22394117
Autor:
Keiya Ozawa, Akihiro Kume, Hiroaki Mizukami, Masashi Urabe, Yasushi Saga, Hiroyuki Mizuguchi, Tomonori Tsukahara, Ryosuke Uchibori
PDF file - 103K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b676ff91c90eccea43c5012887591f0
https://doi.org/10.1158/0008-5472.22394120.v1
https://doi.org/10.1158/0008-5472.22394120.v1
Autor:
Keiya Ozawa, Akihiro Kume, Hiroaki Mizukami, Masashi Urabe, Yasushi Saga, Hiroyuki Mizuguchi, Tomonori Tsukahara, Ryosuke Uchibori
PDF file - 189K, In vivo imaging of NF-kappaB-suppressed MSC accumulation at tumor sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c6117bcccfe135d7824bdfc8be380f
https://doi.org/10.1158/0008-5472.22394123.v1
https://doi.org/10.1158/0008-5472.22394123.v1
Autor:
Keiya Ozawa, Akihiro Kume, Hiroaki Mizukami, Masashi Urabe, Yasushi Saga, Hiroyuki Mizuguchi, Tomonori Tsukahara, Ryosuke Uchibori
PDF file - 235K, Tumor homing ability of MSCs in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5ab430a21fc4b5836e2ecdd2545e1d
https://doi.org/10.1158/0008-5472.22394126.v1
https://doi.org/10.1158/0008-5472.22394126.v1
Autor:
Keiya Ozawa, Akihiro Kume, Hiroaki Mizukami, Masashi Urabe, Yasushi Saga, Hiroyuki Mizuguchi, Tomonori Tsukahara, Ryosuke Uchibori
Mesenchymal stem cells (MSC) accumulate at tumor sites when injected into tumor-bearing mice, perhaps offering cellular vectors for cancer-targeted gene therapy. However, the molecular mechanisms involved in MSC targeting the tumors are presently lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b6a8b0caad615258ed66637a6745eae
https://doi.org/10.1158/0008-5472.c.6503951.v1
https://doi.org/10.1158/0008-5472.c.6503951.v1
Autor:
Keiya Ozawa, Akihiro Kume, Hiroaki Mizukami, Masashi Urabe, Yasushi Saga, Hiroyuki Mizuguchi, Tomonori Tsukahara, Ryosuke Uchibori
PDF file - 115K, Analysis of transduction efficiency and transgene expression levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce6efec744df2527182a1e44e11dc6f
https://doi.org/10.1158/0008-5472.22394129.v1
https://doi.org/10.1158/0008-5472.22394129.v1
Autor:
Yasushi Saga, Mitsuaki Suzuki, Akihiro Kume, Masashi Urabe, Tomonori Tsukahara, Hiroaki Mizukami, Naoto Sato, Ryosuke Uchibori, Keiya Ozawa, Hiroyuki Fujiwara
Publikováno v:
International Journal of Oncology
The major causative agent of cervical cancer is human papilloma virus (HPV); the viral proteins E6 and E7 induce carcinogenesis through the inactivation of the host tumor-suppressor gene. Therefore, the stable expression of specific inhibitors of E6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227aae0b2c311c66d3dcdb243a3c91d6
https://pubmed.ncbi.nlm.nih.gov/29344635
https://pubmed.ncbi.nlm.nih.gov/29344635
Autor:
Chizuru Yamamoto, Masataka Nakamura, M Iwasaki, Hiroaki Mizukami, Hiroyuki Ido, Masashi Urabe, Tomonori Tsukahara, Takeshi Teruya, Koichi Kawakami, Yasushi Saga, Akihiro Kume, Renier J. Brentjens, Keiya Ozawa, Ryosuke Uchibori, N Iwase, Ken Ohmine
Publikováno v:
Gene Therapy. 22:209-215
Engineered T-cell therapy using a CD19-specific chimeric antigen receptor (CD19-CAR) is a promising strategy for the treatment of advanced B-cell malignancies. Gene transfer of CARs to T-cells has widely relied on retroviral vectors, but transposon-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05b6ac56610195e9d241037b0c44592
https://doi.org/10.1038/gt.2014.104
https://doi.org/10.1038/gt.2014.104
Autor:
Akihiro Kume, Satsuki Miyata, Takashi Yamaguchi, Tomonori Tsukahara, Masashi Urabe, Eiju Watanabe, Hiroaki Mizukami, Mutsumi Nagai, Akira Gomi, Keiya Ozawa
Publikováno v:
Neurologia medico-chirurgica
Cytosolic isocitrate dehydrogenase 1 (IDH1) with an R132H mutation in brain tumors loses its enzymatic activity for catalyzing isocitrate to α-ketoglutarate (α-KG) and acquires new activity whereby it converts α-KG to 2-hydroxyglutarate. The IDH1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a069f3e3adf215cfc6c0db1bbef11d9a
https://doi.org/10.2176/nmc.oa2012-0409
https://doi.org/10.2176/nmc.oa2012-0409
Autor:
Hiroaki Mizukami, Manabu Ogura, Takayuki Ito, Masashi Urabe, Akira Onishi, Chiharu Ito, Eiji Kusano, Keiya Ozawa, Tomonori Tsukahara, Tetsu Akimoto, Shigeaki Muto, Akihiro Kume
Publikováno v:
Gene Therapy. 19:476-482
Varying degrees of metabolic abnormalities mediated by chronic inflammation are implicated in the chronic glomerular injuries associated with obesity. Interleukin (IL)-10, a pleiotropic cytokine, exerts anti-inflammatory effects in numerous biologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5a8c6968d496599f59eba018ac9ea7
https://doi.org/10.1038/gt.2011.183
https://doi.org/10.1038/gt.2011.183