Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Tomonori Sasahira"'
Autor:
Phuong Thao Nguyen, Yudai Shimojukkoku, Yuka Kajiya, Yasunobu Oku, Ayami Tomishima, Kaori Shima, Tomonori Sasahira
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0300446 (2024)
In cancer cells, the nuclear transport system is often disrupted, leading to abnormal localization of nuclear proteins and altered gene expression. This disruption can arise from various mechanisms such as mutations in genes that regulate nuclear tra
Externí odkaz:
https://doaj.org/article/d5f02e620a054005b242aaa33ce8d918
Autor:
Hung Trong Hoang, Phuong Thao Nguyen, Nam Cong-Nhat Huynh, Tam Thi-Thanh Nguyen, Trang Thi Huyen Tu, Michael George Botelho, Lan Van Nguyen, Kaori Shima, Tomonori Sasahira
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0286148 (2023)
Amidst the fourth COVID-19 wave in Viet Nam, national lockdowns necessitated the closure of numerous dental schools. To assess DDS (Doctor of Dental Surgery) graduation exams, this study analyzed their 2021 implementation in comparison to onsite exam
Externí odkaz:
https://doaj.org/article/a123acc7911a413db23f9f6b0a7c8a73
Autor:
Tomonori Sasahira, Nobuhiro Ueda, Kazuhiko Yamamoto, Miyako Kurihara, Sayako Matsushima, Ujjal K Bhawal, Tadaaki Kirita, Hiroki Kuniyasu
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92534 (2014)
Prospero homeobox 1 (Prox1) and forkhead box (FOX) C2 regulate angiogenesis and/or lymphangiogenesis. However, the detailed role and function of Prox1 and FOXC2 in cancer remains controversial. In the present study, we examined the expression of Prox
Externí odkaz:
https://doaj.org/article/74166562ecf94c7383046f3ec0fe49a1
Autor:
Hiroki Kuniyasu, Tomonori Sasahira, Ujjal K. Bhawal, Yoshitomo Chihara, Miyako Kurihara, Kazuhiko Yamamoto, Tadaaki Kirita
Publikováno v:
Oncology Reviews, Vol 5, Iss 1 (2011)
Angiogenesis and lymphangiogenesis are the vital factors in tumor progression and metastasis. In this review, we show that high-mobility group box 1 (HMGB1) is responsible for both angiogenesis and lymphangiogenesis in oral squamous cell carcinoma (O
Externí odkaz:
https://doaj.org/article/4da5c979a4f740b8b4dbab6c82ec7c41
Publikováno v:
International Journal of Clinical Oncology. 26:1831-1839
LEM domain containing 1 (LEMD1) is a novel factor involved in the development of oral squamous cell carcinoma (OSCC). We previously performed a microarray analysis and found that serpin peptidase inhibitor, clade E, member 2 (SERPINE2) is an LEMD1-re
Autor:
Tomonori Sasahira, Miyako Kurihara-Shimomura, Yudai Shimojjukoku, Kaori Shima, Tadaaki Kirita
Publikováno v:
Journal of personalized medicine. 12(3)
Head and neck cancer, including oral squamous cell carcinoma (OSCC), is the eighth most common malignancy globally and is characterized by local invasiveness and high nodal metastatic potential. The OSCC incidence is also increasing, and the number o
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 15
International Journal of Molecular Sciences, Vol 21, Iss 5416, p 5416 (2020)
Volume 21
Issue 15
International Journal of Molecular Sciences, Vol 21, Iss 5416, p 5416 (2020)
Despite dramatic progress in cancer diagnosis and treatment, the five-year survival rate of oral squamous cell carcinoma (OSCC) is still only about 50%. Thus, the need for elucidating the molecular mechanisms underlying OSCC is urgent. We previously
Autor:
Tomonori Sasahira, Miyako Kurihara-Shimomura, Tadaaki Kirita, Yukiko Nishiguchi, Hiroyuki Shimomura
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3655, p 3655 (2020)
Volume 21
Issue 10
International Journal of Molecular Sciences, Vol 21, Iss 3655, p 3655 (2020)
Volume 21
Issue 10
Because oral squamous cell carcinomas (OSCCs) have a high potential for locoregional invasion and nodal metastasis, early detection and treatment are essential. A LAP2, emerin, MAN1 (LEM) domain containing 1 (LEMD1) is associated with local progressi
Autor:
Chie Nakashima, Miyako Shimomura-Kurihara, Tadaaki Kirita, Hiroyuki Shimomura, Tomonori Sasahira
Publikováno v:
Pathology. 50:642-647
Summary Oral squamous cell carcinoma (OSCC) has a high potential for local invasion and nodal metastasis. Therefore, early detection and elucidation of the detailed molecular mechanisms underlying OSCC are essential. Dehydrogenase/reductase member 9
Autor:
Tomonori Sasahira, Miyako Kurihara-Shimomura, Hiroyuki Shimomura, Chie Nakashima, Tadaaki Kirita
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 9, Iss 1, p 72 (2019)
Volume 9
Issue 1
Journal of Clinical Medicine, Vol 9, Iss 1, p 72 (2019)
Volume 9
Issue 1
Background: Head and neck cancer, including oral squamous cell carcinoma (OSCC), is the sixth most common malignancy. OSCC has strong invasive ability, and its malignant potential is closely associated with local expansion and lymph node metastasis.