Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Tomonori Igarashi"'
Autor:
Yosuke Miyazaki, Kazuaki Kawai, Tomonori Igarashi, Yoshiyuki Shibata, Kazunori Ikegami, Hisanori Hiro, Seichi Horie, Hiroto Izumi
Publikováno v:
Education and Training.
Introduction Karoshi (death from overwork) has been a difficult challenge in Japanese society for a long time. In July 2015, the cabinet of Japan approved a guideline required by the Act on Promotion of Preventive Measures against Karoshi and other O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03b214ff3494b6beb9fa26d8ff470bc1
https://doi.org/10.1136/oemed-2018-icohabstracts.281
https://doi.org/10.1136/oemed-2018-icohabstracts.281
Autor:
Ian D. Greener, J. Kevin Donahue, Tomonori Igarashi, Tetsuo Sasano, David S. Rosenbaum, Xiaoping Wan, Maria Strom
Publikováno v:
Journal of the American College of Cardiology. 60:1103-1110
Objectives The aim of this study was to evaluate the links between connexin43 (Cx43) expression, myocardial conduction velocity, and ventricular tachycardia in a model of healed myocardial infarction. Background Post-infarction ventricular arrhythmia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c60a15531d166412fecf1e94d23f4e
https://doi.org/10.1016/j.jacc.2012.04.042
https://doi.org/10.1016/j.jacc.2012.04.042
Autor:
Hiroto Izumi, Ryuichi Okayasu, Naoya Miyamoto, Kazuo Chijiiwa, Masaki Shiota, Takamitsu Onitsuka, Ichiro Niina, Tomonori Igarashi, Kimitoshi Kohno, Takeshi Uchiumi, Tetsuro Wakasugi, Takayuki Torigoe
Publikováno v:
Cancer Science. 98:858-863
Modification of transcription factors by anticancer agents plays an important role in both apoptotic and survival signaling. Here we report that both DNA topoisomerase I and II inhibitors such as SN-38 and etoposide, but not cisplatin, 5-fluorouracil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43119b263febcf404fe5ac93593705d1
https://doi.org/10.1111/j.1349-7006.2007.00476.x
https://doi.org/10.1111/j.1349-7006.2007.00476.x
Autor:
Kimitoshi Kohno, Kazuo Chijiiwa, Hiroto Izumi, Takeshi Yoshida, Tetsuro Wakasugi, Hideaki Itoh, Takayuki Torigoe, Izumi Shibuya, Tomonori Igarashi, Ken-ichi Matsuo, Ichiro Niina
Publikováno v:
Journal of Biological Chemistry. 280:1179-1185
Drug-induced modifications of transcription factors play important roles in both apoptosis and survival signaling. The data presented here show that the DNA topoisomerase II poison TAS-103 transactivated the SV40 promoter in a GC-box-dependent manner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897ff1b450a086680876601616cbc203
https://doi.org/10.1074/jbc.m410499200
https://doi.org/10.1074/jbc.m410499200
Autor:
Tomonori Igarashi, Ichiro Niina, Yasutomo Momii, Takayuki Torigoe, Mizuho Tanabe, Michihiko Kuwano, Kimitoshi Kohno, Takuya Imaizumi, Tetsuro Wakasugi, Hiroto Izumi, Takeshi Yoshida, Yoichiro Yoshida, Hiroshi Ishiguchi
Publikováno v:
Current Medicinal Chemistry-Anti-Cancer Agents. 5:15-27
Cisplatin is one of the most potent and widely used anti-cancer agents in the treatment of various solid tumors. However, the development of resistance to cisplatin is a major obstacle in clinical treatment. Several mechanisms are thought to be invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfd3ad286d55b96fa8bf92465743065
https://doi.org/10.2174/1568011053352587
https://doi.org/10.2174/1568011053352587
Autor:
Ken Okumura, Tomonori Igarashi, Takenori Takahata, Tomonori Tateishi, Akihiro Munakata, Norio Yasui-Furukori, Shingo Sasaki
Publikováno v:
Life Sciences. 72:2391-2399
The mutations of the SCN5A gene have been implicated to play a pathogenetic role in Brugada syndrome, which causes ventricular fibrillation. To determine the Brugada-associated mutations in Japanese patients, facilitate pre-symptomatic diagnosis, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d5404e114b2576699852de855a585a
https://doi.org/10.1016/s0024-3205(03)00121-8
https://doi.org/10.1016/s0024-3205(03)00121-8
Autor:
Nobuyuki Yanagihara, Tomonori Igarashi, Masato Tsutsui, Hiroaki Masuzaki, Taro Uchida, Akihide Tanimoto, Yumiko Toyohira, Katsuhiko Noguchi, Masayuki Matsushita, Kumiko Arakaki, Junko Nakasone, Toshihiro Matsuzaki, Mayuko Sakanashi, Hiroaki Shimokawa, Yutaka Otsuji, Susumu Ueno, Yusuke Ohya, Yumi Furuno, Haruaki Kubota, Masahito Tamura, Mika Kina-Tanada, Shogo Ishiuchi
Publikováno v:
Journal of molecular and cellular cardiology. 77
We investigated the effect of subtotal nephrectomy on the incidence of acute myocardial infarction (AMI) in mice deficient in all three nitric oxide synthases (NOSs). Two-thirds nephrectomy (NX) was performed on male triple NOSs −/− mice. The 2/3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f66b5d69a23459e5f821763b3c03ed
https://pubmed.ncbi.nlm.nih.gov/25265498
https://pubmed.ncbi.nlm.nih.gov/25265498
Autor:
Yukinobu, Ito, Shingo, Ohuchi, Tadashi, Okubo, Takanori, Harima, Makoto, Sato, Tomonori, Igarashi
Publikováno v:
Kyobu geka. The Japanese journal of thoracic surgery. 66(9)
Aortic valve replacement using CEP Magna 21 mm bioprosthetic valve was performed because of aortic valve stenosis in a 75-year-old man with maintenance dialysis. In the 39th postoperative month, the bioprosthetic valve malfunction due to calcificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ee7366dba580a441605defc521ca5bf
https://pubmed.ncbi.nlm.nih.gov/23917238
https://pubmed.ncbi.nlm.nih.gov/23917238
Autor:
Maria Strom, David S. Rosenbaum, Ayano Takeuchi, Tomonori Igarashi, J. Kevin Donahue, J. Emanuel Finet, Yoshihisa Fujino, Ian D. Greener
Background— Several lines of evidence have suggested that maintenance of atrial fibrillation (AF) depends on reentrant mechanisms. Maintenance of reentry necessitates a sufficiently short refractory period and/or delayed conduction, and AF has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ff45f741fa1e934d9ef09f5181add7
https://europepmc.org/articles/PMC3260348/
https://europepmc.org/articles/PMC3260348/
Autor:
Mizuho Tanabe, Yasuyuki Sasaguri, Kenji Sugio, Kimitoshi Kohno, Tomonori Igarashi, Ke-Yong Wang, Kosei Yasumoto, Tokuzo Arao, Hidetaka Uramoto, Kazuto Nishio, Hiroto Izumi, Yutaka Otsuji, Takeshi Uchiumi
Publikováno v:
Oncogene. 26(33)
The mechanisms underlying cellular drug resistance have been extensively studied, but little is known about its regulation. We have previously reported that activating transcription factor 4 (ATF4) is upregulated in cisplatin-resistant cells and play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87dc51e6ff084a34f1f705808f4b4469
https://pubmed.ncbi.nlm.nih.gov/17297441
https://pubmed.ncbi.nlm.nih.gov/17297441