Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Tomonori Aoyama"'
Publikováno v:
Gastroenterology Research and Practice, Vol 2010 (2010)
Liver fibrosis occurs as a wound-healing scar response following acute and chronic liver inflammation including alcoholic liver disease, non-alcoholic steatohepatitis, hepatitis B and C, and autoimmune hepatitis. Myofibroblasts, mainly transdifferent
Externí odkaz:
https://doaj.org/article/e31e56df8cd64556a4c5a74dc8afcf79
The Chemical Chaperone 4‐Phenylbutyric Acid Prevents Alcohol‐Induced Liver Injury in Obese KK‐AyMice
Autor:
Kenichi Ikejima, Tomonori Aoyama, Maiko Suzuki, Kumiko Arai, Kazuyoshi Kon, Akira Uchiyama, Sumio Watanabe, Shunhei Yamashina, Takashi Ueno
Publikováno v:
Alcoholism: Clinical and Experimental Research. 43:617-627
Background Co-occurrence of metabolic syndrome and chronic alcohol consumption is increasing worldwide. The present study investigated the effect of the chemical chaperone 4-phenylbutyric acid (PBA)-which has been shown to alleviate dietary steatohep
Autor:
Junko Abe, Ryota Fujitsuka, Fumiki Aiso, Keiichi Sawa, Yoshihiro Ogawa, Shunsuke Okada, Takanori Yamanaka, Hideshi Miyajima, Seiji Nakagawa, Masaki Noguchi, Tomonori Aoyama, Tatsunori Isogai, Hiroyuki Yamashita
Publikováno v:
2019 IEEE International Electron Devices Meeting (IEDM).
For high reliability non-volatile memory cell dielectrics, hydrogen-free deuterated charge-trap SiN and tunnel SiON films are demonstrated. By using deuterated ammonia instead of ammonia as nitridation species in ALD cycles, an ultra-high deuterium/h
Autor:
Atsushi Arakawa, Kazuyoshi Kon, Shunhei Yamashina, Sumio Watanabe, Kenichi Ikejima, Akira Uchiyama, Hirofumi Fukushima, Gentaro Taniguchi, Tomonori Aoyama
Publikováno v:
Hepatology Research. 48:757-767
AIM Hepatic inclusion composed of autophagy-specific substrate p62 is one of the histological features of non-alcoholic fatty liver disease (NAFLD) and can be a precursor to hepatic carcinogenesis. The expression of p62 was enhanced by not only autop
Autor:
Kenichi Ikejima, Hironao Okubo, Akihisa Miyazaki, Kazuyoshi Kon, Tomonori Aoyama, Akira Uchiyama, Sumio Watanabe, Kyoko Kuwahara-Arai, Shigehiro Kokubu, Shunhei Yamashina
Publikováno v:
Laboratory Investigation. 97:890-902
The liver has an immune tolerance against gut-derived products from the portal vein (PV). A disruption of the gut-liver axis leads to liver injury and fibrosis. The spleen is connected to the PV and regulates immune functions. However, possible splen
Autor:
Sumio Watanabe, Kenichi Ikejima, Tomonori Aoyama, Hideyuki Ban, Shunhei Yamashina, Kazuyoshi Kon, Hidekatsu Takada, Akira Uchiyama
Publikováno v:
Internal Medicine
Continuity is required for diet therapy, but it depends on patients. We examined the utility of a new tool, the customized online nutrition guidance system, in patients with nonalcoholic fatty liver disease (NAFLD). Seven patients plotted their body
Autor:
Kumiko Arai, Kenichi Ikejima, Tomonori Aoyama, Sumio Watanabe, Hiromi Kusama, Kazuyoshi Kon, Akira Uchiyama, Shunhei Yamashina
Publikováno v:
Journal of Gastroenterology. 52:611-622
Acetaminophen (APAP) overdose induces severe oxidative stress followed by hepatocyte apoptosis/necrosis. Previous studies have indicated that endoplasmic reticulum (ER) stress is involved in the cell death process. Therefore, we investigated the effe
Autor:
Kazuyoshi Kon, Maki Morinaga, Sumio Watanabe, Tomonori Aoyama, Shunhei Yamashina, Akira Uchiyama, Kumiko Arai, Kenichi Ikejima, Hiromi Kusama
Publikováno v:
Hepatology Research. 47:E44-E54
Aim Pharmacological treatment for metabolic syndrome-related non-alcoholic steatohepatitis has not been established. We investigated the effect of L-carnitine, an essential substance for β-oxidation, on metabolic steatohepatitis in mice. Methods Mal
Autor:
Tomonori Aoyama
Publikováno v:
IEICE Communications Society Magazine. 10:54-66
Autor:
Yutaka Tsukune, Tomonori Aoyama, Atsushi Isoda, Takaaki Miyake, Kazutaka Sunami, Makoto Sasaki, Yukiyoshi Moriuchi, Masaki Iino, Taro Kurihara, Kei Nakajima, Tomomi Takei, Aiko Igarashi, Takeshi Odajima, Koji Nagafuji, Hiroki Sugimori, Takayuki Shimizu, Norio Komatsu, Aya Nakaya, Koji Miyazaki, Tsuyoshi Muta
Publikováno v:
Blood Cancer Journal, Vol 7, Iss 12, Pp 1-6 (2017)
Blood Cancer Journal
Blood Cancer Journal