Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tomonobu Yokomichi"'
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 229-239 (2014)
Ursolic acid (3β-hydroxy-urs-12-en-28-oic acid) is a natural pentacyclic triterpenoid that is present in many plants, including medicinal herbs, and foods. Ursolic acid was initially identified as an inhibitor of the expression of intercellular adhe
Externí odkaz:
https://doaj.org/article/4e18e8adf67c4e219032023e3ba996b8
Autor:
Takao Kataoka, Masayoshi Ando, Shigeru Taketani, Liwei Fu, Yuriko Yamada, Nana Oshima, Tomonobu Yokomichi, Kyoko Morimoto
Publikováno v:
Biomolecules, Vol 1, Iss 1, Pp 32-47 (2011)
Pro-inflammatory cytokines, such as tumor necrosis factor (TNF)-α, induce the expression of a wide variety of genes, including intercellular adhesion molecule-1 (ICAM-1). Ursolic acid (3β-hydroxy-urs-12-en-28-oic acid) was identified to inhibit the
Externí odkaz:
https://doaj.org/article/c487ea6e3cf443e3a3803f28fcaaa06f
Publikováno v:
European Journal of Pharmacology. 767:126-134
Betulinic acid (3β-hydroxy-20(29)-lupen-28-oic acid), oleanolic acid (3β-hydroxy-olean-12-en-28-oic acid), and ursolic acid (3β-hydroxy-urs-12-en-28-oic acid) are close structural isomers of natural pentacyclic triterpenoid carboxylic acids. We re
Publikováno v:
Biological and Pharmaceutical Bulletin. 38:39-47
Cardiac glycosides, which are inhibitors of Na(+)/K(+)-ATPase, are classified into cardenolides and bufadienolides. We have recently shown that two cardenolide glycosides, ouabain and odoroside A, inhibit Na(+)/K(+)-ATPase, thereby preventing nuclear
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 229-239 (2014)
FEBS Open Bio
FEBS Open Bio
Graphical abstract
Highlights • Ursolic acid inhibits cell-surface expression of ICAM-1. • Ursolic acid induces accumulation of high-mannose-type ICAM-1 in ER. • Ursolic acid induces morphological changes of Golgi apparatus. • Ursolic ac
Highlights • Ursolic acid inhibits cell-surface expression of ICAM-1. • Ursolic acid induces accumulation of high-mannose-type ICAM-1 in ER. • Ursolic acid induces morphological changes of Golgi apparatus. • Ursolic ac