Effect of Grinder Pretreatment for Easy Disintegration of Chitin into Nanofiber

Autor: Hiroyuki Saimoto, Yihun Fantahun Aklog, Hironori Izawa, Tomone Nagae, Minoru Morimoto, Shinsuke Ifuku

Publikováno v: Journal of Nanoscience and Nanotechnology. 17:5037-5041

Chitin nanofibers were prepared by grinder pretreatments and subsequent mechanical treatment using a high-pressure water-jet (HPWJ) system. From SEM observations, grinder pretreatment improved disintegration efficiency in subsequent HPWJ treatment. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a1a428242c8d04028c34109fe85125a
https://doi.org/10.1166/jnn.2017.14223

Biomaterials based on freeze dried surface-deacetylated chitin nanofibers reinforced with sulfobutyl ether β-cyclodextrin gel in wound dressing applications

Autor: Tsubasa Tanou, Fumitoshi Hirayama, Ryo Tabuchi, Daisuke Iohara, Kaneto Uekama, Yoshiharu Okamoto, Masaki Otagiri, Shinsuke Ifuku, Kazuo Azuma, Tomone Nagae, Ryotaro Izumi, Makoto Anraku

Publikováno v: International Journal of Pharmaceutics. 511:1080-1087

A freeze-dried gel composed of surface-deacetylated chitin nanofibers (SDACNFs), reinforced with an anionic cyclodextrin, sulfobutyl ether β-cyclodextrin (SBE-β-CD) was evaluated for treating wounds in a rat model, and the results were compared wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a642474624c03b99f0283d0cf8d761
https://doi.org/10.1016/j.ijpharm.2016.08.019

Effects of Surface-Deacetylated Chitin Nanofibers in an Experimental Model of Hypercholesterolemia.

Autor: Kazuo Azuma¹ kazu-azuma@muses.tottori-u.ac.jp, Tomone Nagae² tomonekomame@gmail.com, Takeshi Nagai³ nagait@jfrl.or.jp, Hironori Izawa² h-izawa@chem.tottori-u.ac.jp, Minoru Morimoto⁴ morimoro@chem.tottori-u.ac.jp, Yusuke Murahata¹ ymurahata@muses.tottori-u.ac.jp, Tomohiro Osaki¹ tosaki@muses.tottori-u.ac.jp, Takeshi Tsuka¹ tsuka@muses.tottori-u.ac.jp, Tomohiro Imagawa¹ imagawat@muses.tottori-u.ac.jp, Norihiko Ito¹ taro@muses.tottori-u.ac.jp, Yoshiharu Okamoto¹ yokamoto@muses.tottori-u.ac.jp, Hiroyuki Saimoto² saimoto@chem.tottori-u.ac.jp, Shinsuke Ifuku² sifuku@chem.tottori-u.ac.jp

Publikováno v: International Journal of Molecular Sciences. Aug2015, Vol. 16 Issue 8, p17445-17455. 11p. 5 Charts.

Preparation of chitin nanofibers by surface esterification of chitin with maleic anhydride and mechanical treatment

Autor: Minoru Morimoto, Hironori Izawa, Yihun Fantahun Aklog, Hiroyuki Saimoto, Shinsuke Ifuku, Tomone Nagae

Publikováno v: Aklog, Yihun Fantahun. Nagae, Tomone. Izawa, Hironori. et al. Preparation of chitin nanofibers by surface esterification of chitin with maleic anhydride and mechanical treatment. Carbohydrate Polymers. 153. 55-59. 2016-11-20.

Esterification with maleic anhydride significantly improved the mechanical disintegration of chitin into uniform 10-nm nanofibers. Nanofibers with 0.25 ° of esterification were homogeneously dispersed in basic water due to the carboxylate salt on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f18d5c6f3e3586ce4565844747056ac
https://pubmed.ncbi.nlm.nih.gov/27561471

Effects of Oral Administration of Chitin Nanofiber on Plasma Metabolites and Gut Microorganisms

Autor: Yoshiharu Okamoto, Ryotaro Izumi, Hironori Izawa, Shinsuke Ifuku, Mari Kawata, Yusuke Murahata, Norihiko Ito, Takeshi Tsuka, Kazuo Azuma, Minoru Morimoto, Hiroyuki Saimoto, Tomohiro Osaki, Tomohiro Imagawa, Tomone Nagae

Publikováno v: International Journal of Molecular Sciences
Volume 16
Issue 9
Pages 21931-21949
International Journal of Molecular Sciences, Vol 16, Iss 9, Pp 21931-21949 (2015)

The aim of this study was to examine the effects of oral administration of chitin nanofibers (CNFs) and surface-deacetylated (SDA) CNFs on plasma metabolites using metabolome analysis. Furthermore, we determined the changes in gut microbiota and feca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482fe8db6a92fd943206d6e029f89abf