Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Tomonari Harada"'
Autor:
Kazuki Kagami, MD, Masaru Obokata, MD, PhD, Tomonari Harada, MD, PhD, Yuki Saito, MD, PhD, Ayami Naito, MD, Hidemi Sorimachi, MD, PhD, Naoki Yuasa, MD, Toshimitsu Kato, MD, PhD, Naoki Wada, MD, PhD, Takeshi Adachi, MD, PhD, Hideki Ishii, MD, PhD
Publikováno v:
CJC Open, Vol 5, Iss 5, Pp 380-391 (2023)
Background: Hospitalization with a first episode of heart failure (HF) is a serious event associated with poor clinical outcomes in HF with preserved ejection fraction (HFpEF). Identification of HFpEF via detection of elevated left ventricular fillin
Externí odkaz:
https://doaj.org/article/e2a99f08f2e343f7b2bd38e2ddaa5a2d
Autor:
Ayami Naito, Masaru Obokata, Kazuki Kagami, Tomonari Harada, Hidemi Sorimachi, Naoki Yuasa, Yuki Saito, Toshimitsu Kato, Naoki Wada, Takeshi Adachi, Hideki Ishii
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 48, Iss , Pp 101255- (2023)
Aims: Anemia is common in patients with heart failure with preserved ejection fraction (HFpEF) and is associated with exercise intolerance. However, there are limited data on how anemia contributes to reduced exercise capacity in patients with HFpEF.
Externí odkaz:
https://doaj.org/article/9cb67446c03d403ab09b89a97fdee592
Autor:
Yuki Saito, Masaru Obokata, Tomonari Harada, Kazuki Kagami, Makoto Murata, Hidemi Sorimachi, Toshimitsu Kato, Naoki Wada, Yasuo Okumura, Hideki Ishii
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Cardiopulmonary exercise testing (CPET) may potentially differentiate heart failure (HF) with preserved ejection fraction (HFpEF) from noncardiac causes of dyspnea (NCD). While contemporary guidelines for HF recommend using CPET for identify
Externí odkaz:
https://doaj.org/article/8425b5a01a1e40af8fb18c049fd9829d
Autor:
Ryo Kawakami, Hiroaki Sunaga, Tatsuya Iso, Ryosuke Kaneko, Norimichi Koitabashi, Masaru Obokata, Tomonari Harada, Hiroki Matsui, Tomoyuki Yokoyama, Masahiko Kurabayashi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Ketone body β-hydroxybutyrate (βOHB) and fibroblast growth factor-21 (FGF21) have been proposed to mediate systemic metabolic response to fasting. However, it remains elusive about the signaling elicited by ketone and FGF21 in the heart. S
Externí odkaz:
https://doaj.org/article/8ef047ff176a4e448e80b6e0f81fb16f
Autor:
Reika Nagata, Tomonari Harada, Kazunori Omote, Hiroyuki Iwano, Kotaro Yoshida, Toshimitsu Kato, Koji Kurosawa, Toshiyuki Nagai, Toshihisa Anzai, Masaru Obokata
Publikováno v:
ESC Heart Failure, Vol 9, Iss 2, Pp 1454-1462 (2022)
Abstract Aims Right‐sided filling pressure is elevated in some patients with heart failure (HF) and preserved ejection fraction (HFpEF). We hypothesized that right atrial pressure (RAP) would represent the cumulative burden of abnormalities in the
Externí odkaz:
https://doaj.org/article/084dc49c60c848748c20c1f3d74f1d86
Autor:
Shiro Amanai, Tomonari Harada, Kazuki Kagami, Kuniko Yoshida, Toshimitsu Kato, Naoki Wada, Masaru Obokata
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Exercise intolerance is a primary manifestation in patients with heart failure with preserved ejection fraction (HFpEF) and is associated with abnormal hemodynamics and a poor quality of life. Two multiparametric scoring systems have been pr
Externí odkaz:
https://doaj.org/article/7884f2fc981c4f72816000717b9b1d22
Autor:
Yuko Seki, Masaru Obokata, Tomonari Harada, Kazuki Kagami, Hidemi Sorimachi, Yuki Saito, Toshimitsu Kato, Hideki Ishii
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 44, Iss , Pp 101162- (2023)
Background: Despite the obesity paradox, visceral adiposity is associated with poor clinical outcomes in patients with heart failure with preserved ejection fraction (HFpEF). However, it remains unclear whether a relationship between visceral fat and
Externí odkaz:
https://doaj.org/article/f88051025bc34245a8bc08e8a9d5e331
Autor:
Tomonari Harada, Takeshi Araki, Hiroaki Sunaga, Kazuki Kagami, Kuniko Yoshida, Toshimitsu Kato, Ryo Kawakami, Junichi Tomono, Naoki Wada, Tatsuya Iso, Masahiko Kurabayashi, Masaru Obokata
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Elevated intracardiac pressure at rest and/or exercise is a fundamental abnormality in heart failure with preserved ejection fraction (HFpEF). Fatty acid-binding protein 1 (FABP1) is proposed to be a sensitive biomarker for liver injury. We
Externí odkaz:
https://doaj.org/article/d048d3b5e65e4da18cfca697b4cccf5a
Autor:
Kazuki Kagami, Masaru Obokata, Tomonari Harada, Toshimitsu Kato, Naoki Wada, Takeshi Adachi, Hideki Ishii
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 13 (2022)
Background Exercise‐induced high heart rate may impair exercise tolerance by reducing diastolic filling time and ventricular filling in heart failure with preserved ejection fraction (HFpEF). Given the importance of chronotropic response, we hypoth
Externí odkaz:
https://doaj.org/article/cf99356acbd24719a66de9b4ddc79f44
Autor:
Kazuki Kagami, Hiroaki Sunaga, Hidemi Sorimachi, Tomonari Harada, Kuniko Yoshida, Toshimitsu Kato, Koji Kurosawa, Ryo Kawakami, Norimichi Koitabashi, Tatsuya Iso, Takeshi Adachi, Masahiko Kurabayashi, Masaru Obokata
Publikováno v:
ESC Heart Failure, Vol 8, Iss 2, Pp 1494-1501 (2021)
Abstract Aims Few biomarkers to evaluate pathophysiological changes in extra‐cardiac tissues have been identified in patients with heart failure (HF). Fatty acid‐binding protein 1 (FABP), also known as liver FABP, is predominantly expressed in th
Externí odkaz:
https://doaj.org/article/2c5e73a491e7436a99b91f63ed4fb4f6