Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Tomonaga Ichikawa"'
Autor:
Yu Wang, Shunsuke Shimosaki, Emi Ikebe, Hidekatsu Iha, Jun-ichi Yamamoto, Nichole Fife, Tomonaga Ichikawa, Mitsuo Hori, Masao Ogata, Yoshiyuki Tsukamoto, Naoki Hijiya, Masatsugu Moriyama, Shotaro Hagiwara, Shuichi Kusano, Masumichi Saito, Kamruddin Ahmed, Akira Nishizono, Hiroshi Handa, Kazuhiro Morishita
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell neoplasia associated with human T-cell leukemia virus type 1 (HTLV-1) infection and has an extremely poor prognosis. Lenalidomide (LEN; a second-generation immunomodulatory drug [IMiD]) has
Externí odkaz:
https://doaj.org/article/c652ad6387c14272840172d06da6e59c
Autor:
Tomonaga Ichikawa, Akira Suekane, Shingo Nakahata, Hidekatsu Iha, Kazuya Shimoda, Takashi Murakami, Kazuhiro Morishita
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2842 (2024)
N-myc downstream-regulated gene 2 (NDRG2), which is a tumour suppressor, is frequently lost in many types of tumours, including adult T-cell leukaemia/lymphoma (ATL). The downregulation of NDRG2 expression is involved in tumour progression through th
Externí odkaz:
https://doaj.org/article/38464602364044098ce23d872311bc17
Autor:
Yanuar Rahmat Fauzi, Shingo Nakahata, Syahrul Chilmi, Tomonaga Ichikawa, Phawut Nueangphuet, Ryoji Yamaguchi, Tatsufumi Nakamura, Kazuya Shimoda, Kazuhiro Morishita
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256320 (2021)
Adult T-cell leukemia/lymphoma (ATLL) originates from human T-cell leukemia virus type 1 (HTLV-1) infection due to the activation of the nuclear factor-κB (NF-κB) signaling pathway to maintain proliferation and survival. An important mechanism of t
Externí odkaz:
https://doaj.org/article/dadc559e545343faba763fd0ec5d7197
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8391 (2009)
Targeting Nrf2 signaling appears to be an attractive approach for the treatment of maladaptive cardiac remodeling and dysfunction; however, pharmacological modulation of the Nrf2 pathway in the cardiovascular system remains to be established. Herein,
Externí odkaz:
https://doaj.org/article/66fc5dd01b224c0f83669f1b7b400c41
Publikováno v:
Anticancer Research. 42:4743-4752
Autor:
Kazuhiro Morishita, Yoshihiro Yamashita, Mitsuru Futakuchi, Ryoji Yamaguchi, Takashi Baba, Kentaro Nagai, Koji Yamamoto, Yuri Tagawa, Yudai Kondo, Shingo Nakahata, Tomonaga Ichikawa, Tomohiro Tamura
Sequences of the primers for Reverse-transcription polymerase chain reaction (RT-PCR) and Quantitative real-time PCR analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabbea8adaa3b2a17219be47a65773b4
https://doi.org/10.1158/0008-5472.22418040
https://doi.org/10.1158/0008-5472.22418040
Autor:
Kazuhiro Morishita, Yoshihiro Yamashita, Mitsuru Futakuchi, Ryoji Yamaguchi, Takashi Baba, Kentaro Nagai, Koji Yamamoto, Yuri Tagawa, Yudai Kondo, Shingo Nakahata, Tomonaga Ichikawa, Tomohiro Tamura
Loss of the tumor suppressor NDRG2 has been implicated in the development of oral squamous cell carcinoma (OSCC), acting by modulating PI3K/AKT-mediated dephosphorylation of PTEN at S380/S382/T383 (STT). Here, we show that the majority of OSCC tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad2fbdc91ce37b868fbc4aadca9ae9a
https://doi.org/10.1158/0008-5472.c.6510012
https://doi.org/10.1158/0008-5472.c.6510012
Autor:
Kazuhiro Morishita, Yoshihiro Yamashita, Mitsuru Futakuchi, Ryoji Yamaguchi, Takashi Baba, Kentaro Nagai, Koji Yamamoto, Yuri Tagawa, Yudai Kondo, Shingo Nakahata, Tomonaga Ichikawa, Tomohiro Tamura
Supplemental Figure 1. Keratin staining of cervical lymph nodes from Ndrg2-deficient mice treated with 4-NQO. Supplementary figure related to Figure 2; Supplemental Figure 2. Effect of 4-NQO treatment on an OSCC cell line was observed through the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a19609a654f181f79a40da16429e1f
https://doi.org/10.1158/0008-5472.22418043.v1
https://doi.org/10.1158/0008-5472.22418043.v1
Autor:
Kazuhiro Morishita, Yoshihiro Yamashita, Mitsuru Futakuchi, Ryoji Yamaguchi, Takashi Baba, Kentaro Nagai, Koji Yamamoto, Yuri Tagawa, Yudai Kondo, Shingo Nakahata, Tomonaga Ichikawa, Tomohiro Tamura
Supplemental figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2583842ccbc7dea2bc4d31150060c704
https://doi.org/10.1158/0008-5472.22418049
https://doi.org/10.1158/0008-5472.22418049
Autor:
Kazuhiro Morishita, Yoshihiro Yamashita, Mitsuru Futakuchi, Ryoji Yamaguchi, Takashi Baba, Kentaro Nagai, Koji Yamamoto, Yuri Tagawa, Yudai Kondo, Shingo Nakahata, Tomonaga Ichikawa, Tomohiro Tamura
supplementary tables: Supplemental Table 1. Expression rates of immunohistochemical staining of NDRG2 versus p-Akt or p-PTEN in tumors from OSCC patients. Supplementary table related to Figure 1; Supplemental Table 2. Incidence of tumour formation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4059c776469f74f3b9bfdb8daf4a45f
https://doi.org/10.1158/0008-5472.22418037
https://doi.org/10.1158/0008-5472.22418037