Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tomomitsu Iida"'
Autor:
Anikó Kárpáti, Takeo Yoshikawa, Tadaho Nakamura, Tomomitsu Iida, Takuro Matsuzawa, Haruna Kitano, Ryuichi Harada, Kazuhiko Yanai
Publikováno v:
Journal of Pharmacological Sciences, Vol 137, Iss 2, Pp 122-128 (2018)
Astrocytes play key roles in regulating brain homeostasis and neuronal activity. This is, in part, accomplished by the ability of neurotransmitters in the synaptic cleft to bind astrocyte membrane receptors, activating signalling cascades that regula
Externí odkaz:
https://doaj.org/article/d2badc78d4944a48a4ee5c8b968f0b29
Autor:
Tadaho Nakamura, Takeo Yoshikawa, Fumito Naganuma, Attayeb Mohsen, Tomomitsu Iida, Yamato Miura, Akira Sugawara, Kazuhiko Yanai
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 36-41 (2015)
Pancreatic α‐cells secrete glucagon to maintain energy homeostasis. Although histamine has an important role in energy homeostasis, the expression and function of histamine receptors in pancreatic α‐cells remains unknown. We found that the hist
Externí odkaz:
https://doaj.org/article/c00d4d6626c04ff4a7d6ba18b6ee136e
Publikováno v:
Current topics in behavioral neurosciences. 59
Microglia, a category of glial cells in the central nervous system (CNS), have attracted much attention because of their important role in neuroinflammation. Many translational studies are currently ongoing to discover novel drugs targeting microglia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9094dcae3813024766d4fedb42ad56a6
https://pubmed.ncbi.nlm.nih.gov/35538301
https://pubmed.ncbi.nlm.nih.gov/35538301
Publikováno v:
The Functional Roles of Histamine Receptors ISBN: 9783031169960
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38028644bc0a2c35c49d577e992edcb7
https://doi.org/10.1007/7854_2022_322
https://doi.org/10.1007/7854_2022_322
Autor:
Tadaho Nakamura, Fumito Naganuma, Atushi Yanai, Anikó Kárpáti, Tomomitsu Iida, Takeo Yoshikawa, Kazuhiko Yanai, Nobuyuki Okamura, Takuro Matsuzawa, Takatoshi Mochizuki, Yamato Miura, Asuka Mogi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports
Scientific Reports
Histamine is a neurotransmitter that regulates diverse physiological functions including the sleep-wake cycle. Recent studies have reported that histaminergic dysfunction in the brain is associated with neuropsychiatric disorders. Histamine N-methylt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e7d67fad54de814bf47250b203fab2
http://link.springer.com/article/10.1038/s41598-017-16019-8
http://link.springer.com/article/10.1038/s41598-017-16019-8
Autor:
Rob Leurs, Takeo Yoshikawa, Tadaho Nakamura, Tomomitsu Iida, Manabu Tashiro, Kazuhiko Yanai, Ai Yanai
Publikováno v:
Yanai, K, Yoshikawa, T, Yanai, A, Nakamura, T, Iida, T, Leurs, R & Tashiro, M 2017, ' The clinical pharmacology of non-sedating antihistamines ', Pharmacology and Therapeutics, vol. 178, pp. 148-156 . https://doi.org/10.1016/j.pharmthera.2017.04.004
We previously reported on brain H1 receptor occupancy measurements of antihistamines in human brain using [11C]doxepin and positron emission tomography (PET). We proposed the use of brain H1 receptor occupancy to classify antihistamines objectively i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1f3bd1405ee54ec1d090461767a5e2
https://doi.org/10.1016/j.pharmthera.2017.04.004
https://doi.org/10.1016/j.pharmthera.2017.04.004
Autor:
Anikó Kárpáti, Tomomitsu Iida, Takuro Matsuzawa, Fumito Naganuma, Tadaho Nakamura, Takeo Yoshikawa, Kazuhiko Yanai, Asuka Mogi, Yamato Miura, Ryuichi Harada
Publikováno v:
FEBS Open Bio
The dysregulation of monoamine clearance in the central nervous system occurs in various neuropsychiatric disorders, and the role of polyspecific monoamine transporters in monoamine clearance is increasingly highlighted in recent studies. However, no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730f753c1ff25d262942a9df60ffab69
https://doi.org/10.1002/2211-5463.12183
https://doi.org/10.1002/2211-5463.12183
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 93:3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::497c9eebd7e65d04a681960c3c921dad
https://doi.org/10.1254/jpssuppl.93.0_3-p-272
https://doi.org/10.1254/jpssuppl.93.0_3-p-272
Autor:
Tomomitsu Iida, Yu Yamaguchi, Akira Sugawara, Tadaho Nakamura, Kazuhiko Yanai, Haruna Kitano, Ryuichi Harada, Takeo Yoshikawa, Takuro Matsuzawa, Anikó Kárpáti
Publikováno v:
Biochemical and biophysical research communications. 499(3)
Heparan sulfate (HS), a linear polysaccharide, is involved in diverse biological functions of various tissues. HS is expressed in pancreatic β-cells and may be involved in β-cell functions. However, the importance of HS for β-cell function remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70ac55c43d763ef0199e0d4215b23e9
https://pubmed.ncbi.nlm.nih.gov/29605295
https://pubmed.ncbi.nlm.nih.gov/29605295
Autor:
Attayeb Mohsen, Tomomitsu Iida, Takeo Yoshikawa, Takuro Matsuzawa, Fumito Naganuma, Tadaho Nakamura, Kazuhiko Yanai, Ryuichi Harada, Yamato Miura, Ren Iwata
Publikováno v:
Glia. 63:1213-1225
Histamine is a physiological amine which initiates a multitude of physiological responses by binding to four known G-protein coupled histamine receptor subtypes as follows: histamine H1 receptor (H1 R), H2 R, H3 R, and H4 R. Brain histamine elicits n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13da66e0eebe1295e80f355df4c67783
https://doi.org/10.1002/glia.22812
https://doi.org/10.1002/glia.22812