Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tomomichi Chonan"'
Autor:
Daisuke Yamamoto, Akira Hiratate, Tomomichi Chonan, Miyoko Yashiro, Daisuke Wakasugi, Fusayo Io, Hiroko Koretsune, Hiroaki Tanaka, Ayumi Ohoka-Sugita, Takahiro Oi
Publikováno v:
Bioorganicmedicinal chemistry. 19(5)
Novel (4-piperidinyl)-piperazine derivatives were synthesized and evaluated as ACC1/2 non-selective inhibitors. Optimization of the substituents on the nitrogen of the piperidine ring led to the identification of the fluorine substituted tert-butoxyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ea50dd0e25d528dafcbbd54f81a2a0
https://pubmed.ncbi.nlm.nih.gov/21324704
https://pubmed.ncbi.nlm.nih.gov/21324704
Publikováno v:
ChemInform. 28
A diene-transmissive hetero-Diels–Alder reaction of cross- conjugated azatrienes, which provides a novel and efficient synthetic method for ring-fused, nitrogen-heterocyclic frameworks such as quinazolin-2-ones and pyrimido[5,4-c]- pyridazin-6-ones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55912cdcb71cd1544a0cb0e471f28ed1
https://doi.org/10.1002/chin.199741191
https://doi.org/10.1002/chin.199741191
Autor:
Daisuke Yamamoto, Akira Hiratate, Hiroaki Tanaka, Tomomichi Chonan, Miyoko Yashiro, Hiroko Koretsune, Daisuke Wakasugi, Ayumi Ohoka-Sugita, Fusayo Io, Takahiro Oi
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(13)
Acetyl-CoA carboxylases (ACCs), the rate limiting enzymes in de novo lipid synthesis, play important roles in modulating energy metabolism. The inhibition of ACC has demonstrated promising therapeutic potential for treating obesity and type 2 diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a1ddd265e2e82373209c50ac95e2b3
https://pubmed.ncbi.nlm.nih.gov/20537533
https://pubmed.ncbi.nlm.nih.gov/20537533
Autor:
Daisuke Wakasugi, Takahiro Oi, Miyoko Yashiro, Hiroaki Tanaka, Ayumi Ohoka-Sugita, Tomomichi Chonan, Akira Hiratate, Fusayo Io, Hiroko Koretsune, Daisuke Yamamoto
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(23)
Acetyl-CoA carboxylases (ACCs), the rate limiting enzymes in de novo lipid synthesis, play important roles in modulating energy metabolism. The inhibition of ACC has demonstrated promising therapeutic potential for treating obesity and type 2 diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e245dbea7d6c7f08aaf8c4ff99264571
https://pubmed.ncbi.nlm.nih.gov/19853443
https://pubmed.ncbi.nlm.nih.gov/19853443
Autor:
Tomomichi Chonan, Charles N. Serhan, Siva Elangovan, Yee-Ping Sun, Makoto Arita, Nicos A. Petasis, Song Hong, Sungwhan F. Oh, Jasim Uddin
Publikováno v:
The Journal of biological chemistry. 281(32)
The resolvins (Rv) are lipid mediators derived from omega-3 polyunsaturated fatty acids that act within a local inflammatory milieu to stop leukocyte recruitment and promote resolution. Resolvin E1 (RvE1; (5S,12R,18R)-trihydroxy-6Z,8E,10E,14Z,16E-eic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4790ac9d1f9c4f8b7a5628d85e7c8a
https://pubmed.ncbi.nlm.nih.gov/16757471
https://pubmed.ncbi.nlm.nih.gov/16757471
Publikováno v:
Chemical Communications. :1013-1014
A diene-transmissive hetero-Diels–Alder reaction of cross- conjugated azatrienes, which provides a novel and efficient synthetic method for ring-fused, nitrogen-heterocyclic frameworks such as quinazolin-2-ones and pyrimido[5,4-c]- pyridazin-6-ones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44967cb32fc68631dce00a1324bda094
https://doi.org/10.1039/a701575e
https://doi.org/10.1039/a701575e
Autor:
Arita, Makoto1,2, Sungwhan F. Oh1,2, Tomomichi Chonan1, Song Hong1,2, Elangovan, Siva1,2, Yee-Ping Sun1, Uddin, Jasim3, Petasis, Nicos A.3, Serhan, Charles N.1,2 cnserhan@zeus.bwh.harvard.edu
Publikováno v:
Journal of Biological Chemistry. 8/11/2006, Vol. 281 Issue 32, p22847-22854. 8p. 6 Diagrams, 2 Charts.