Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tomomi Ogasawara"'
Autor:
Tohru Takashi, Mika Yokoyama, Jun Chiba, Fumito Muro, Takao Horiuchi, Yutaka Iigou, Tomomi Ogasawara, Nobuo Machinaga, Atsushi Nakayama, Shin Iimura, Yuichi Ochiai, Gensuke Takayama, Yoshiyuki Yoneda, Yoshimi Takata, Tomoe Taira, Yuichi Sugimoto, Masao Tsubokawa
Publikováno v:
Chemical and Pharmaceutical Bulletin. 54:1515-1529
A novel series of benzoic acid derivatives as VLA-4 antagonists were synthesized. Optimization, focusing on activity and lipophilicity needed for cell permeability, resulted in the identification of 15b and 15e with good activity (IC50 = 1.6 nM each)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b500c4c2d5a713262c292b29b04d0a
https://doi.org/10.1248/cpb.54.1515
https://doi.org/10.1248/cpb.54.1515
Publikováno v:
Differentiation; research in biological diversity. 86(1-2)
Oncostatin M (OSM), one of the IL-6 family cytokines, inhibits adipogenic differentiation and stimulates osteoblastogenic differentiation from human bone marrow mesenchymal stem cells (hBMSCs). This functional study of OSM enabled us to develop a two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a83503bbacd8543d4b86a982aeffec
https://pubmed.ncbi.nlm.nih.gov/23995451
https://pubmed.ncbi.nlm.nih.gov/23995451
Autor:
Tomomi, OGASAWARA
Publikováno v:
日赤医学 = The Japanese Red Cross Medical Journal. 66(1):265
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::97c40997c7700ee58603c86cf3e8d0c2
http://id.nii.ac.jp/1063/00006236/
http://id.nii.ac.jp/1063/00006236/