Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Tomomi M. Yamamoto"'
Autor:
Lindsay J. Wheeler, Zachary L. Watson, Lubna Qamar, Tomomi M. Yamamoto, Brandon T. Sawyer, Kelly D. Sullivan, Santosh Khanal, Molishree Joshi, Veronique Ferchaud-Roucher, Harry Smith, Lauren A. Vanderlinden, Sky W. Brubaker, Cecilia M. Caino, Hyunmin Kim, Joaquin M. Espinosa, Jennifer K. Richer, Benjamin G. Bitler
Publikováno v:
iScience, Vol 19, Iss , Pp 474-491 (2019)
Summary: High-grade serous ovarian cancers (HGSOCs) arise from exfoliation of transformed cells from the fallopian tube, indicating that survival in suspension, and potentially escape from anoikis, is required for dissemination. We report here the re
Externí odkaz:
https://doaj.org/article/d7cae58c70cf4b989ef74c7cfa5a6c7f
Autor:
Lindsay W. Brubaker, Donald S. Backos, Vu T. Nguyen, Philip Reigan, Tomomi M Yamamoto, Elizabeth R. Woodruff, Ritsuko Iwanaga, Michael F. Wempe, Vijay Kumar, Christianne Persenaire, Zachary L. Watson, Benjamin G. Bitler
Publikováno v:
Expert Opinion on Therapeutic Targets. :1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05bb72902b5fcb68b31e7422a9211081
https://doi.org/10.1080/14728222.2023.2218614
https://doi.org/10.1080/14728222.2023.2218614
Autor:
Alexandra McMellen, Tomomi M. Yamamoto, Lubna Qamar, Brooke E. Sanders, Lily L. Nguyen, Daniela Ortiz Chavez, Jaidev Bapat, Amber Berning, Miriam D. Post, Joshua Johnson, Kian Behbakht, Elmar Nurmemmedov, Edward B. Chuong, Benjamin G. Bitler
Publikováno v:
Mol Cancer Res
High-grade serous ovarian cancer (HGSOC) is the deadliest ovarian cancer histotype due in-part to the lack of therapeutic options for chemotherapy-resistant disease. PARP inhibitors (PARPi) represent a targeted treatment. However, PARPi resistance is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830ad527d4c63b130ee0192ec77dc0d7
https://doi.org/10.1158/1541-7786.mcr-22-0102
https://doi.org/10.1158/1541-7786.mcr-22-0102
Autor:
Benjamin G. Bitler, Kian Behbakht, Margaret Neville, Saketh R. Guntupalli, Elizabeth R. Woodruff, Heidi K. Baumgartner, Dana M. Davis, Patricia G. Webb, Tomomi M. Yamamoto
High-grade serous ovarian cancer is the deadliest gynecologic malignancy due to progression to resistant disease. Claudin-4 is classically defined as a tight junction protein and is often associated with epithelial cancers. Claudin-4 is aberrantly ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150c8a5faa4a0a8ff02ce46844d96f3c
https://doi.org/10.1158/1535-7163.c.6543310
https://doi.org/10.1158/1535-7163.c.6543310
Autor:
Benjamin G. Bitler, Neil Johnson, Paul S. Mischel, Elizabeth M. Swisher, Silvia Casadei, Kian Behbakht, Zachary L. Watson, Andrew V. Kossenkov, Kristen M. Turner, Andrea J. Bernhardy, Yifan Wang, Bing Xia, Allen L. Alcivar, Hua Li, Tomomi M. Yamamoto, Pyoung Hwa Park
Immunoprecipitation of BRCA2 . List of proteins identified via mass spectrometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c3719a3603c8d1f9fbeb54a1d1fd00
https://doi.org/10.1158/1535-7163.22506633.v1
https://doi.org/10.1158/1535-7163.22506633.v1
Autor:
Benjamin G. Bitler, Kian Behbakht, Margaret Neville, Saketh R. Guntupalli, Elizabeth R. Woodruff, Heidi K. Baumgartner, Dana M. Davis, Patricia G. Webb, Tomomi M. Yamamoto
Supplementary Table from Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac01d736f5cf41d967f9953e227aeb8
https://doi.org/10.1158/1535-7163.22522225
https://doi.org/10.1158/1535-7163.22522225
Autor:
Benjamin G. Bitler, Kian Behbakht, Margaret Neville, Saketh R. Guntupalli, Elizabeth R. Woodruff, Heidi K. Baumgartner, Dana M. Davis, Patricia G. Webb, Tomomi M. Yamamoto
Supplementary Figure from Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000a889c6b466db4272d5c7ddbb4716a
https://doi.org/10.1158/1535-7163.22522234
https://doi.org/10.1158/1535-7163.22522234
Autor:
Benjamin G. Bitler, Neil Johnson, Paul S. Mischel, Elizabeth M. Swisher, Silvia Casadei, Kian Behbakht, Zachary L. Watson, Andrew V. Kossenkov, Kristen M. Turner, Andrea J. Bernhardy, Yifan Wang, Bing Xia, Allen L. Alcivar, Hua Li, Tomomi M. Yamamoto, Pyoung Hwa Park
Patients harboring germline breast cancer susceptibility genes 1 and 2 (BRCA1/2) mutations are predisposed to developing breast, pancreatic, and ovarian cancers. BRCA2 plays a critical role in homologous recombination (HR) DNA repair and deleterious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e778c74a3f8f3abad668636d1d3a106
https://doi.org/10.1158/1535-7163.c.6538452.v1
https://doi.org/10.1158/1535-7163.c.6538452.v1
Autor:
Benjamin G. Bitler, Miriam D. Post, Amber Berning, Elizabeth R. Woodruff, Alexandra McMellen, Tomomi M. Yamamoto, Brooke E. Sanders
Supplementary Data from Targeting DUSP Activity as a Treatment for High-Grade Serous Ovarian Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85510fb81d81e87bdb098984e7f18cb
https://doi.org/10.1158/1535-7163.22523043.v1
https://doi.org/10.1158/1535-7163.22523043.v1
Autor:
Benjamin G. Bitler, Isabel R. Schlaepfer, Kian Behbakht, Jennifer K. Richer, Zachary L. Watson, Alexandra McMellen, Tomomi M. Yamamoto, Lubna Qamar, Brandon T. Sawyer
Figure S1. HGSOC cells cultured in suspension upregulate Carnitine and Fatty Acid Metabolism. Figure S2. Confirmation of CPT1A antibody specificity. Figure S3. Oxygen consumption rate (OCR) in suspension cells and oleic acid rescue of anoikis. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14bb67eb67bccae46751d5398b5ce697
https://doi.org/10.1158/1541-7786.22517206.v1
https://doi.org/10.1158/1541-7786.22517206.v1