Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tomomi Hosono"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract We previously demonstrated that cinnamon extract (CE) alleviates streptozotocin-induced type 1 diabetes in rats. The present study aimed to elucidate the detailed molecular target of cinnamon in cultured adipocytes and epididymal adipose tis
Externí odkaz:
https://doaj.org/article/21a7982da4b449fd91328a386a67ecef
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 47:33-37
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 137(8)
Several case studies have reported a possible drug interaction between warfarin and tramadol where tramadol coadministration enhanced the antithrombotic effects of warfarin. To assess this drug interaction, changes in prothrombin time-international n
Autor:
Tony Wyss-Coray, Markus Britschgi, Shiori Ohtake-Niimi, Tomomi Hosono-Fukao, Kazuchika Nishitsuji, Toin H. van Kuppevelt, Md. Motarab Hossain, Hitomi Hoshino, Koji Kimata, Hiroyasu Akatsu, Kenji Uchimura, Makoto Michikawa
Publikováno v:
The American Journal of Pathology. 180:2056-2067
Alzheimer's disease (AD) is characterized by extracellular cerebral accumulation of amyloid β peptide (Aβ). Heparan sulfate (HS) is a glycosaminoglycan that is abundant in the extracellular space. The state of sulfation within the HS chain influenc
Autor:
Kenji Uchimura, Shiori Ohtake-Niimi, Kazuchika Nishitsuji, Tomomi Hosono-Fukao, Md. Motarab Hossain, Toin H. van Kuppevelt, Makoto Michikawa
Publikováno v:
Journal of Neuroscience Research, 89, 11, pp. 1840-8
Journal of Neuroscience Research, 89, 1840-8
Journal of Neuroscience Research, 89, 1840-8
Contains fulltext : 98280.pdf (Publisher’s version ) (Closed access) RB4CD12 is a phage display antibody that recognizes a heparan sulfate (HS) glycosaminoglycan epitope. The epitope structure is proposed to contain a trisulfated disaccharide, [-Id
Autor:
Yuki Tanaka, Kazunari Watanabe, Toyohiko Ariga, Takashi Hosono, Taiichiro Seki, Shun Suda, Rie Tanaka, Jun Ogihara, Tomomi Hosono-Fukao, Kazuhiro Watanabe
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 78:1415-1417
To identify the molecular target of diallyl trisulfide (DATS) in human leukemic cell line U937, we examined modification of thiol group(s) of cellular proteins by the redox 2D PAGE. A unique protein spot appeared by DATS treatment was identified to b
Autor:
Taiichiro Seki, Tomomi Hosono-Fukao, Yuji Iitsuka, Rie Tanaka, Toyohiko Ariga, Kahoru Inada, Takashi Hosono, Isao Hasegawa, Haruhisa Yamada
Publikováno v:
Carcinogenesis
Alk(en)yl trisulfides (R-SSS-R') are organosulfur compounds produced by crushed garlic and other Allium vegetables. We found that these compounds exhibit potent anticancer effects through the reaction with microtubules, causing cell cycle arrest. Nin
Autor:
Takashi Hosono, Toyohiko Ariga, Tomomi Hosono-Fukao, Kazunari Watanabe, Taiichiro Seki, Kazuhiro Watanabe
Publikováno v:
Bioscience, biotechnology, and biochemistry. 78(8)
We reported the regulation of protein function by oxidative modification of the specific cysteine residue(s) by diallyl trisulfide (DATS). In this study, we examined if DATS modifies the cysteine residue of thioredoxin (Trx) by urea-polyacryl amide g
Autor:
Tomomi, Hosono-Fukao, Shiori, Ohtake-Niimi, Hitomi, Hoshino, Markus, Britschgi, Hiroyasu, Akatsu, Md Motarab, Hossain, Kazuchika, Nishitsuji, Toin H, van Kuppevelt, Koji, Kimata, Makoto, Michikawa, Tony, Wyss-Coray, Kenji, Uchimura
Publikováno v:
The American journal of pathology. 180(5)
Alzheimer's disease (AD) is characterized by extracellular cerebral accumulation of amyloid β peptide (Aβ). Heparan sulfate (HS) is a glycosaminoglycan that is abundant in the extracellular space. The state of sulfation within the HS chain influenc
Autor:
Toyohiko Ariga, Yuji Iitsuka, Takashi Hosono, Yuki Tanaka, Taiichiro Seki, Tomomi Hosono-Fukao
Publikováno v:
Oncology research. 18(11-12)
Of the compounds contained in or derived from garlic (Allium sativum L.), alk(en)yl sulfides are known to be responsible for most of the physiological or neutraceutical functions of garlic. We previously found that diallyl trisulfide (DATS) is a pote