Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Tomomi Hashidate‐Yoshida"'
The role of lysophosphatidylcholine acyltransferase 2 in osteoblastic differentiation of C2C12 cells
Autor:
Shirou Tabe, Hisako Hikiji, Tomomi Hashidate‐Yoshida, Hideo Shindou, Takao Shimizu, Kazuhiro Tominaga
Publikováno v:
FEBS Open Bio, Vol 14, Iss 9, Pp 1490-1502 (2024)
Glycerophospholipids, a primary component of cellular membranes, play important structural and functional roles in cells. In the remodelling pathway (Lands' cycle), the concerted actions of phospholipase As and lysophospholipid acyltransferases (LPLA
Externí odkaz:
https://doaj.org/article/4fb2163549ec45c59df8158b2051d795
Autor:
Shuto Tanaka, Masataka Kawakita, Hikaru Yasui, Koichi Sudo, Fumie Itoh, Masato Sasaki, Nobuyuki Shibata, Hiromitsu Hara, Yoichiro Iwakura, Tomomi Hashidate-Yoshida, Hideo Shindou, Takao Shimizu, Taiki Oyama, Himawari Matsunaga, Kazuhiko Takahara
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract Acute immune responses with excess production of cytokines, lipid/chemical mediators, or coagulation factors, often result in lethal damage. In addition, the innate immune system utilizes multiple types of receptors that recognize neurotrans
Externí odkaz:
https://doaj.org/article/1ce32dd6b57e4157970de60655be50fa
Sphingosine-1-phosphate promotes liver fibrosis in metabolic dysfunction-associated steatohepatitis.
Autor:
Yosuke Osawa, Hironari Kawai, Keigo Nakashima, Yuichi Nakaseko, Daisuke Suto, Keisuke Yanagida, Tomomi Hashidate-Yoshida, Taizo Mori, Sachiyo Yoshio, Takaaki Ohtake, Hideo Shindou, Tatsuya Kanto
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303296 (2024)
AimMetabolic dysfunction-associated steatohepatitis (MASH) is one of the most prevalent liver diseases and is characterized by steatosis and the accumulation of bioactive lipids. This study aims to understand the specific lipid species responsible fo
Externí odkaz:
https://doaj.org/article/a39a40adb53b45e78a3e925d9fbcd021
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
Peripheral nerve injury (PNI) induces neuronal hyperexcitability, which underlies neuropathic pain. The emergence of RNA sequencing technologies has enabled profiling of transcriptional changes in pathological conditions. However, these approaches do
Externí odkaz:
https://doaj.org/article/576e878e97854bf58c925925e96aaf3c
Autor:
Fumie Hamano, Suzumi Tokuoka, Tomomi Hashidate-Yoshida, Hideo Shindou, Takao Shimizu, Yoshihiro Kita
Publikováno v:
Bio-Protocol, Vol 10, Iss 9 (2020)
In mammalian organisms, fatty acids (FAs) exist mostly in esterified forms, as building blocks of phospholipids, triglycerides, and cholesteryl esters, while some exist as non-esterified free FAs. The absolute quantification of FA species in total li
Externí odkaz:
https://doaj.org/article/424f2c2a733b4d51b7f0e2653bbc6b93
Autor:
Hiroshi Kobayashi, Takayuki Morikawa, Ayumi Okinaga, Fumie Hamano, Tomomi Hashidate-Yoshida, Shintaro Watanuki, Daisuke Hishikawa, Hideo Shindou, Fumio Arai, Yasuaki Kabe, Makoto Suematsu, Takao Shimizu, Keiyo Takubo
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 145-158.e9 (2019)
Summary: Hematopoietic stem cells (HSCs) maintain lifelong hematopoiesis by remaining quiescent in the bone marrow niche. Recapitulation of a quiescent state in culture has not been achieved, as cells rapidly proliferate and differentiate in vitro. A
Externí odkaz:
https://doaj.org/article/0d5b7262cdce4be7b9a78ccf3be0990f
Autor:
Tomomi Hashidate-Yoshida, Takeshi Harayama, Daisuke Hishikawa, Ryo Morimoto, Fumie Hamano, Suzumi M Tokuoka, Miki Eto, Miwa Tamura-Nakano, Rieko Yanobu-Takanashi, Yoshiko Mukumoto, Hiroshi Kiyonari, Tadashi Okamura, Yoshihiro Kita, Hideo Shindou, Takao Shimizu
Publikováno v:
eLife, Vol 4 (2015)
Polyunsaturated fatty acids (PUFAs) in phospholipids affect the physical properties of membranes, but it is unclear which biological processes are influenced by their regulation. For example, the functions of membrane arachidonate that are independen
Externí odkaz:
https://doaj.org/article/e77477d61e2740d5a54c570fec3d11ef
Autor:
Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate‐Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara
Publikováno v:
Hepatology. 77:77-91
Immunotherapy has become the standard-of-care treatment for hepatocellular carcinoma (HCC), but its efficacy remains limited. To identify immunotherapy-susceptible HCC, we profiled the molecular abnormalities and tumor immune microenvironment (TIME)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d234b3344152904598e20d8ee64eeda
https://doi.org/10.1002/hep.32573
https://doi.org/10.1002/hep.32573
Autor:
Takae Tanosaki, Yu Mikami, Hideo Shindou, Tomoyuki Suzuki, Tomomi Hashidate-Yoshida, Keisuke Hosoki, Shizuko Kagawa, Jun Miyata, Hiroki Kabata, Katsunori Masaki, Ryuji Hamamoto, Hidenori Kage, Naoya Miyashita, Kosuke Makita, Hirotaka Matsuzaki, Yusuke Suzuki, Akihisa Mitani, Takahide Nagase, Takao Shimizu, Koichi Fukunaga
Publikováno v:
Inflammation. 45:1765-1779
Chronic obstructive pulmonary disease (COPD) is primarily caused by inhalation of cigarette smoke and is the third leading cause of death worldwide. Pulmonary surfactant, a complex of phospholipids and proteins, plays an essential role in respiration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9238ebb73d595af757cdfa76562a37e5
https://doi.org/10.1007/s10753-022-01659-4
https://doi.org/10.1007/s10753-022-01659-4
Autor:
Yoshihiro Kita, Fumie Hamano, Tomoyuki Suzuki, Takeshi Harayama, Tomomi Hashidate-Yoshida, Daisuke Hishikawa, Takao Shimizu, Hideo Shindou, Nobuo N. Noda, Kiyotake Miura, Kazuaki Matoba, Koichi Yuki
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(6)
Platelet-activating factor (PAF) is a potent proinflammatory phospholipid mediator that elicits various cellular functions and promotes several pathological events, including anaphylaxis and neuropathic pain. PAF is biosynthesized by two types of lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5516bac0fd50b830b6a4c9c6e61feb54
https://pubmed.ncbi.nlm.nih.gov/33956375
https://pubmed.ncbi.nlm.nih.gov/33956375