Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tomomi G. Otsuji"'
Autor:
Tomomi G. Otsuji, Jiang Bin, Azumi Yoshimura, Misayo Tomura, Daiki Tateyama, Itsunari Minami, Yoshihiro Yoshikawa, Kazuhiro Aiba, John E. Heuser, Taito Nishino, Kouichi Hasegawa, Norio Nakatsuji
Publikováno v:
Stem Cell Reports, Vol 2, Iss 5, Pp 734-745 (2014)
Utilizing human pluripotent stem cells (hPSCs) in cell-based therapy and drug discovery requires large-scale cell production. However, scaling up conventional adherent cultures presents challenges of maintaining a uniform high quality at low cost. In
Externí odkaz:
https://doaj.org/article/a7da3ee2651749578143de9250850ca9
Autor:
Itsunari Minami, Kohei Yamada, Tomomi G. Otsuji, Takuya Yamamoto, Yan Shen, Shinya Otsuka, Shin Kadota, Nobuhiro Morone, Maneesha Barve, Yasuyuki Asai, Tatyana Tenkova-Heuser, John E. Heuser, Motonari Uesugi, Kazuhiro Aiba, Norio Nakatsuji
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1448-1460 (2012)
Human pluripotent stem cells (hPSCs), including embryonic stem cells and induced pluripotent stem cells, are potentially useful in regenerative therapies for heart disease. For medical applications, clinical-grade cardiac cells must be produced from
Externí odkaz:
https://doaj.org/article/6308896a15144f35836539ec46846f5f
Autor:
Tomoyuki Sumi, Kaori Yamauchi, Norio Nakatsuji, Tomomi G. Otsuji, Eihachiro Kawase, Hirofumi Suemori, Itsunari Minami
Publikováno v:
Genes to Cells. 15:1216-1227
Cardiomyocytes arise from cells that migrate to the mid-to-anterior region of the primitive streak (PS) during embryogenesis. We previously showed that canonical Wnt/β-catenin pathway signaling leads to the development of nascent PS populations from
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 9, p e45010 (2012)
PLoS ONE, Vol 7, Iss 9, p e45010 (2012)
Cardiomyocytes (CMs) derived from human embryonic stem cells (hESCs) or human induced pluripotent stem cells (hiPSCs) are functionally heterogeneous, display insufficient biological efficacy and generally possess the electrophysiological properties s
Autor:
Christine L. Mummery, Kazuwa Nakao, Tadashi Ikeda, Masataka Fujiwara, Peishi Yan, Hideki Uosaki, Satoshi Matsuoka, Koichiro Kuwahara, Masato Nakagawa, Norio Nakatsuji, Genta Narazaki, Ryuzo Sakata, Hiroyuki Fukushima, Shinya Yamanaka, Hiroyuki Matsuda, Masaki Harada, Kazutoshi Takahashi, Jun K. Yamashita, Tomomi G. Otsuji, Keisuke Okita
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16734 (2011)
PLoS ONE
PLoS ONE, 6(2)
PLoS ONE
PLoS ONE, 6(2)
Induced pluripotent stem cells (iPSCs) are novel stem cells derived from adult mouse and human tissues by reprogramming. Elucidation of mechanisms and exploration of efficient methods for their differentiation to functional cardiomyocytes are essenti
Autor:
Kaori, Yamauchi, Tomoyuki, Sumi, Itsunari, Minami, Tomomi G, Otsuji, Eihachiro, Kawase, Norio, Nakatsuji, Hirofumi, Suemori
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 15(12)
Cardiomyocytes arise from cells that migrate to the mid-to-anterior region of the primitive streak (PS) during embryogenesis. We previously showed that canonical Wnt/β-catenin pathway signaling leads to the development of nascent PS populations from
Publikováno v:
Stem Cell Research. (3):201-213
The field of drug testing currently needs a new integrated assay system, as accurate as systems using native tissues, that will allow us to predict arrhythmia risks of candidate drugs and the relationship between genetic mutations and acquired electr
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45010 (2012)
Cardiomyocytes (CMs) derived from human embryonic stem cells (hESCs) or human induced pluripotent stem cells (hiPSCs) are functionally heterogeneous, display insufficient biological efficacy and generally possess the electrophysiological properties s
Externí odkaz:
https://doaj.org/article/6ec5312a6ef544858f23adb08e3622f0
Autor:
Masataka Fujiwara, Peishi Yan, Tomomi G Otsuji, Genta Narazaki, Hideki Uosaki, Hiroyuki Fukushima, Koichiro Kuwahara, Masaki Harada, Hiroyuki Matsuda, Satoshi Matsuoka, Keisuke Okita, Kazutoshi Takahashi, Masato Nakagawa, Tadashi Ikeda, Ryuzo Sakata, Christine L Mummery, Norio Nakatsuji, Shinya Yamanaka, Kazuwa Nakao, Jun K Yamashita
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16734 (2011)
Induced pluripotent stem cells (iPSCs) are novel stem cells derived from adult mouse and human tissues by reprogramming. Elucidation of mechanisms and exploration of efficient methods for their differentiation to functional cardiomyocytes are essenti
Externí odkaz:
https://doaj.org/article/ebcc9e28bec240eb83991bb68d5b334c