Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Tomomi Akita"'
Autor:
Ryosuke Tanino, Yukari Tsubata, Takamasa Hotta, Tamio Okimoto, Yoshihiro Amano, Mayumi Takechi, Tetsuya Tanaka, Tomomi Akita, Mamiko Nagase, Chikamasa Yamashita, Koichiro Wada, Takeshi Isobe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Emphysema limits airflow and causes irreversible progression of chronic obstructive pulmonary disease (COPD). Strain differences must be considered when selecting mouse models of COPD, owing to disease complexity. We previously reported that
Externí odkaz:
https://doaj.org/article/808c1c5d1d5947a18da3fd7110b74ed7
Autor:
Junpei Takahashi, Yudai Ueta, Daisuke Yamada, Sachie Sasaki‐Hamada, Takashi Iwai, Tomomi Akita, Chikamasa Yamashita, Akiyoshi Saitoh, Jun‐Ichiro Oka
Publikováno v:
Neuropsychopharmacology Reports, Vol 42, Iss 4, Pp 492-501 (2022)
Abstract Aim We previously reported that oxytocin, a peptide hormone, can reverse the β‐amyloid peptide (25–35) (Aβ25–35)‐induced impairments of the murine hippocampal synaptic plasticity. In this study, we examined the effects of oxytocin
Externí odkaz:
https://doaj.org/article/ff4dd2c485744413a1596cf3f380bc36
Autor:
Tomomi Akita, Kazuaki Oda, Satoru Narukawa, Yuki Morita, Kota Tange, Yuta Nakai, Chikamasa Yamashita
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 838 (2023)
Chronic obstructive pulmonary disease (COPD) results in obstructive ventilatory impairment caused by emphysema, and current treatment is limited to symptomatic therapy or lung transplantation. Therefore, the development of new treatments to repair al
Externí odkaz:
https://doaj.org/article/58fad632906f493a9059358d1445260e
Autor:
Toshihiro Nakamura, Kunihiko Kiuchi, Koji Fukuzawa, Mitsuru Takami, Tomomi Akita, Hideya Suehiro, Makoto Takemoto, Jun Sakai, Atsusuke Yatomi, Yusuke Sonoda, Hiroyuki Takahara, Kazutaka Nakasone, Kyoko Yamamoto, Ken‐ichi Hirata, Takashi Ashihara
Publikováno v:
Journal of Arrhythmia, Vol 35, Iss 5, Pp 733-736 (2019)
Abstract A 41‐year‐old man with persistent atrial fibrillation (AF) underwent radiofrequency (RF) catheter ablation using an online real‐time phase mapping system: ExTRa Mapping. Box isolation could not terminate AF. Subsequently, RF applicatio
Externí odkaz:
https://doaj.org/article/053a62e1d5384b50b04cc15ad1e9d948
Autor:
Tomomi Akita, Yuki Morita, Takehiro Kawai, Kazuaki Oda, Kota Tange, Yuta Nakai, Chikamasa Yamashita
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 37 (2022)
Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis and emphysema, and current drug treatments target its symptoms. Thus, the development of a therapeutic drug to repair alveolar destruction is urgently needed. Our pre
Externí odkaz:
https://doaj.org/article/daaa5c829bf14b0684fdbad55111dad2
Autor:
Mitsuru Takami, Tetsuya Hara, Tomoaki Okimoto, Masaki Suga, Koji Fukuzawa, Kunihiko Kiuchi, Hideya Suehiro, Tomomi Akita, Makoto Takemoto, Toshihiro Nakamura, Jun Sakai, Atsusuke Yatomi, Kazutaka Nakasone, Yusuke Sonoda, Kyoko Yamamoto, Hiroyuki Takahara, Ken‐ichi Hirata
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 7 (2021)
Background Medium‐dose (25 gray) x‐ray radiation therapy has recently been performed on patients with refractory ventricular tachyarrhythmias. Unlike x‐ray, carbon ion and proton beam radiation can deliver most of their energy to the target tis
Externí odkaz:
https://doaj.org/article/965c43877649486ca99bdc6042daa98c
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 759 (2022)
Human lung deposition data is non-mandatory for drug approval but very useful for the development of orally inhaled drug products. Lung deposition of inhaled drugs can be quantified by radionuclide imaging, for which one of the first considerations i
Externí odkaz:
https://doaj.org/article/8d477b4c355c46d69a4cc39e0097cf25
Autor:
Jun Kurose, Kunihiko Kiuchi, Koji Fukuzawa, Shumpei Mori, Hirotoshi Ichibori, Hiroki Konishi, Yayoi Taniguchi, Kiyohiro Hyogo, Hiroshi Imada, Hideya Suehiro, Yu‐ichi Nagamatsu, Tomomi Akita, Makoto Takemoto, Ken‐ichi Hirata, Shinsuke Shimoyama, Yoshiaki Watanabe, Tatsuya Nishii, Noriyuki Negi, Katsusuke Kyotani
Publikováno v:
Journal of Arrhythmia, Vol 34, Iss 2, Pp 158-166 (2018)
Abstract Background Rhythm outcomes after the pulmonary vein isolation (PVI) using the cryoballoon (CB) are reported to be excellent. However, the lesions after CB ablation have not been well discussed. We sought to characterize and compare the lesio
Externí odkaz:
https://doaj.org/article/8d487fe91b9e42a28630f779e1b9f19d
Autor:
Kahori Miyamoto, Misato Yanagisawa, Hiroaki Taga, Hiromichi Yamaji, Tomomi Akita, Chikamasa Yamashita
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 632 (2021)
It has been previously reported that active vitamin D3 (VD3) is a candidate drug that can repair alveolar damage in chronic obstructive pulmonary disease at a very low dose. We herein report the optimization of a very low-dose formulation of VD3 for
Externí odkaz:
https://doaj.org/article/5a7a5b3510c24ea29f4cebfda721da7b
Systemic Delivery of hGhrelin Derivative by Lyophilizate for Dry Powder Inhalation System in Monkeys
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 233 (2021)
Ghrelin is the peptide that increases the hunger sensation and food intake and is expected to be clinically applied for treatment of diseases such as cachexia and anorexia nervosa. In the clinical application of ghrelin, injections are problematic in
Externí odkaz:
https://doaj.org/article/d597dd7a57df468fb0ddd6fb331325cf