Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tomomi Hosono-Fukao"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract We previously demonstrated that cinnamon extract (CE) alleviates streptozotocin-induced type 1 diabetes in rats. The present study aimed to elucidate the detailed molecular target of cinnamon in cultured adipocytes and epididymal adipose tis
Externí odkaz:
https://doaj.org/article/21a7982da4b449fd91328a386a67ecef
Autor:
Tony Wyss-Coray, Markus Britschgi, Shiori Ohtake-Niimi, Tomomi Hosono-Fukao, Kazuchika Nishitsuji, Toin H. van Kuppevelt, Md. Motarab Hossain, Hitomi Hoshino, Koji Kimata, Hiroyasu Akatsu, Kenji Uchimura, Makoto Michikawa
Publikováno v:
The American Journal of Pathology. 180:2056-2067
Alzheimer's disease (AD) is characterized by extracellular cerebral accumulation of amyloid β peptide (Aβ). Heparan sulfate (HS) is a glycosaminoglycan that is abundant in the extracellular space. The state of sulfation within the HS chain influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7146b4989cd60c5cfb3412036b633abd
https://doi.org/10.1016/j.ajpath.2012.01.015
https://doi.org/10.1016/j.ajpath.2012.01.015
Autor:
Kenji Uchimura, Shiori Ohtake-Niimi, Kazuchika Nishitsuji, Tomomi Hosono-Fukao, Md. Motarab Hossain, Toin H. van Kuppevelt, Makoto Michikawa
Publikováno v:
Journal of Neuroscience Research, 89, 11, pp. 1840-8
Journal of Neuroscience Research, 89, 1840-8
Journal of Neuroscience Research, 89, 1840-8
Contains fulltext : 98280.pdf (Publisher’s version ) (Closed access) RB4CD12 is a phage display antibody that recognizes a heparan sulfate (HS) glycosaminoglycan epitope. The epitope structure is proposed to contain a trisulfated disaccharide, [-Id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb862accd9a0ae585ab175b6eeefc42e
https://hdl.handle.net/2066/98280
https://hdl.handle.net/2066/98280
Autor:
Yuki Tanaka, Kazunari Watanabe, Toyohiko Ariga, Takashi Hosono, Taiichiro Seki, Shun Suda, Rie Tanaka, Jun Ogihara, Tomomi Hosono-Fukao, Kazuhiro Watanabe
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 78:1415-1417
To identify the molecular target of diallyl trisulfide (DATS) in human leukemic cell line U937, we examined modification of thiol group(s) of cellular proteins by the redox 2D PAGE. A unique protein spot appeared by DATS treatment was identified to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7bb608c621976ae743058cfed66b77
https://doi.org/10.1080/09168451.2014.921563
https://doi.org/10.1080/09168451.2014.921563
Autor:
Taiichiro Seki, Tomomi Hosono-Fukao, Yuji Iitsuka, Rie Tanaka, Toyohiko Ariga, Kahoru Inada, Takashi Hosono, Isao Hasegawa, Haruhisa Yamada
Publikováno v:
Carcinogenesis
Alk(en)yl trisulfides (R-SSS-R') are organosulfur compounds produced by crushed garlic and other Allium vegetables. We found that these compounds exhibit potent anticancer effects through the reaction with microtubules, causing cell cycle arrest. Nin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b6d0e925f8dd7a15a5575f04d69035
https://doi.org/10.1093/carcin/bgn124
https://doi.org/10.1093/carcin/bgn124
Autor:
Takashi Hosono, Toyohiko Ariga, Tomomi Hosono-Fukao, Kazunari Watanabe, Taiichiro Seki, Kazuhiro Watanabe
Publikováno v:
Bioscience, biotechnology, and biochemistry. 78(8)
We reported the regulation of protein function by oxidative modification of the specific cysteine residue(s) by diallyl trisulfide (DATS). In this study, we examined if DATS modifies the cysteine residue of thioredoxin (Trx) by urea-polyacryl amide g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59a934f3da358b893da3f97bdccb1c2
https://pubmed.ncbi.nlm.nih.gov/25130747
https://pubmed.ncbi.nlm.nih.gov/25130747
Autor:
Tomomi, Hosono-Fukao, Shiori, Ohtake-Niimi, Hitomi, Hoshino, Markus, Britschgi, Hiroyasu, Akatsu, Md Motarab, Hossain, Kazuchika, Nishitsuji, Toin H, van Kuppevelt, Koji, Kimata, Makoto, Michikawa, Tony, Wyss-Coray, Kenji, Uchimura
Publikováno v:
The American journal of pathology. 180(5)
Alzheimer's disease (AD) is characterized by extracellular cerebral accumulation of amyloid β peptide (Aβ). Heparan sulfate (HS) is a glycosaminoglycan that is abundant in the extracellular space. The state of sulfation within the HS chain influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97e9d8f4ef24389dd89d07d086e1a647
https://pubmed.ncbi.nlm.nih.gov/22429964
https://pubmed.ncbi.nlm.nih.gov/22429964
Autor:
Toyohiko Ariga, Yuji Iitsuka, Takashi Hosono, Yuki Tanaka, Taiichiro Seki, Tomomi Hosono-Fukao
Publikováno v:
Oncology research. 18(11-12)
Of the compounds contained in or derived from garlic (Allium sativum L.), alk(en)yl sulfides are known to be responsible for most of the physiological or neutraceutical functions of garlic. We previously found that diallyl trisulfide (DATS) is a pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2ece0aade643cf9542279c0e8a951a
https://pubmed.ncbi.nlm.nih.gov/20939433
https://pubmed.ncbi.nlm.nih.gov/20939433
Autor:
Tomomi Hosono-Fukao, Noriko Sugaya, Kenji Uchimura, Steven D. Rosen, Renhong Tang, Guido J. Jenniskens, Motarab Hossain, Toin H. van Kuppevelt, Koji Kimata
Publikováno v:
Glycobiology, 20, 2, pp. 175-86
Glycobiology, 20, 175-86
Glycobiology, 20, 175-86
Contains fulltext : 88885.pdf (Publisher’s version ) (Closed access) Heparan sulfates (HS) bind a diversity of protein ligands on the cell surface and in the extracellular matrix and thus can modulate cell signaling. The state of sulfation in gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af436745a89396e891e8d29931482615
https://hdl.handle.net/2066/88885
https://hdl.handle.net/2066/88885
Publikováno v:
The Journal of nutrition. 139(12)
Alk(en)yl sulfides have been found to be responsible for the anticancer, antithrombotic, and antioxidant effects of garlic. We sought to identify the most potent structure of sulfides that exhibits a hepatoprotective effect against carbon tetrachlori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7afe33c3a4572524a66e46054314dfd
https://pubmed.ncbi.nlm.nih.gov/19812219
https://pubmed.ncbi.nlm.nih.gov/19812219