Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Tomomi, Hatanaka"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Corticotropin-releasing factor (CRF) is mainly secreted from the hypothalamic paraventricular nuclei and plays a crucial role in stress-related responses. Recent studies have reported that CRF is a neuromodulator in the central nervous syste
Externí odkaz:
https://doaj.org/article/dbf406862dda4832a92109e633121076
Autor:
Tomoharu Takeuchi, Risa Nakamura, Megumi Hamasaki, Midori Oyama, Shinjiro Hamano, Tomomi Hatanaka
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Objective Galectins are sugar-binding proteins that participate in many biological processes, such as immunity, by regulating host immune cells and their direct interaction with pathogens. They are involved in mediating infection by Schistos
Externí odkaz:
https://doaj.org/article/026fa76716be47e183aa3601d911ee45
Publikováno v:
BioTech, Vol 13, Iss 1, p 6 (2024)
Chitosan, a natural cationic polysaccharide derived from crustaceans and shellfish shells, is known for its advantageous biological properties, including biodegradability, biocompatibility, and antibacterial activity. Chitosan and its composite mater
Externí odkaz:
https://doaj.org/article/4a84101e919d49009afe8f5c7d256b4c
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 121 (2024)
Galectin-1 (Gal-1) is an evolutionarily conserved sugar-binding protein found in intra- and extracellular spaces. Extracellularly, it binds to glycoconjugates with β-galactoside(s) and functions in various biological phenomena, including immunity, c
Externí odkaz:
https://doaj.org/article/f6ae3e0707d14477814cf4f8d83099c7
Autor:
Akira Oka, Atsushi Takagi, Etsuko Komiyama, Nagisa Yoshihara, Shuhei Mano, Kazuyoshi Hosomichi, Shingo Suzuki, Yuko Haida, Nami Motosugi, Tomomi Hatanaka, Minoru Kimura, Mahoko Takahashi Ueda, So Nakagawa, Hiromi Miura, Masato Ohtsuka, Masayuki Tanaka, Tomoyoshi Komiyama, Asako Otomo, Shinji Hadano, Tomotaka Mabuchi, Stephan Beck, Hidetoshi Inoko, Shigaku Ikeda
Publikováno v:
EBioMedicine, Vol 57, Iss , Pp 102810- (2020)
ABSTRACT: Background: Alopecia areata (AA) is considered a highly heritable, T-cell-mediated autoimmune disease of the hair follicle. However, no convincing susceptibility gene has yet been pinpointed in the major histocompatibility complex (MHC), a
Externí odkaz:
https://doaj.org/article/7cb874ff2ece4cad90ef4fbd8faaa171
Autor:
Tomomi Hatanaka, Khampeeraphan Ramphai, Shun Takimoto, Hiromi Kanda, Nami Motosugi, Minoru Kimura, Tomotaka Mabuchi, Midori Oyama, Tomoharu Takeuchi, Yosuke Okamura
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 431 (2022)
Xeroderma pigmentosum (XP) is a rare autosomal recessive hereditary disorder. As patients with XP are deficient in nucleotide excision repair, they show severe photosensitivity symptoms. Although skin protection from ultraviolet (UV) radiation is ess
Externí odkaz:
https://doaj.org/article/38054268e43c42d1a86a978a9aabf578
Autor:
Tomomi Hatanaka, Tomoharu Takeuchi, Yasuhiro Horimoto, Yoichiro Arata, Mayumi Tamura, Midori Oyama, Sachie Nakatani, Kenji Kobata
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1501-1505
Osteoclasts are the only bone-resorbing cells in organisms and understanding their differentiation mechanism is crucial for the treatment of osteoporosis. In the present study, we investigated the effect of Thiamet G, an O-GlcNAcase specific inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f998d51f55e58246a3ca7a8edf5a08
https://doi.org/10.1248/bpb.b20-00221
https://doi.org/10.1248/bpb.b20-00221
Autor:
Toru Tanaka, Takashi Tanikawa, Yoichiro Arata, Norihiko Fujii, Tomoharu Takeuchi, Mayumi Tamura, Tomomi Hatanaka, Seishi Kishimoto, Saori Oka
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:356-360
Galectins are a group of animal lectins characterized by their specificity for β-galactosides. Of these, galectin-2 (Gal-2) is predominantly expressed in the gastrointestinal tract. In the current study, we used a mouse gastric mucous fraction to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0750c91adf0d0c6fa9625b284eb4fc
https://doi.org/10.1248/bpb.b19-00705
https://doi.org/10.1248/bpb.b19-00705
Autor:
Tomoharu Takeuchi, Tomomi Hatanaka, Megumi Hamasaki, Yoichiro Arata, Shinjiro Hamano, Kenji Ishiwata, Mayumi Tamura
Publikováno v:
Glycobiology. 29(6):504-512
Galactoseβ1-4Fucose (GalFuc) is a unique disaccharide found in invertebrates including nematodes. A fungal galectin CGL2 suppresses nematode development by recognizing the galactoseβ1-4fucose epitope. The Caenorhabditis elegans galectin LEC-6 recog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ca57f7f29afff25c4ee6c75bb19319
https://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-glycob_cwz022
https://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-glycob_cwz022
Autor:
Tomoharu, Takeuchi, Yasuhiro, Horimoto, Midori, Oyama, Sachie, Nakatani, Kenji, Kobata, Mayumi, Tamura, Yoichiro, Arata, Tomomi, Hatanaka
Publikováno v:
Biologicalpharmaceutical bulletin. 43(10)
Osteoclasts are the only bone-resorbing cells in organisms and understanding their differentiation mechanism is crucial for the treatment of osteoporosis. In the present study, we investigated the effect of Thiamet G, an O-GlcNAcase specific inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::407cf51829e07f10526b781eaccd706c
https://pubmed.ncbi.nlm.nih.gov/32999159
https://pubmed.ncbi.nlm.nih.gov/32999159