Výsledky vyhledávání - "Tomoko Yamakawa"

Akademický článek

TM2D3, a mammalian homologue of Drosophila neurogenic gene product Almondex, regulates surface presentation of Notch receptors

Autor: Wataru Masuda, Tomoko Yamakawa, Rieko Ajima, Katsuya Miyake, Toshifumi Umemiya, Kazuhiko Azuma, Jun-ichi Tamaru, Makoto Kiso, Puspa Das, Yumiko Saga, Kenji Matsuno, Motoo Kitagawa

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)

Abstract Notch signaling is an evolutionarily conserved mechanism required for numerous types of cell fate decisions in metazoans. It mediates short-range communication between cells with receptors and ligands, both of which are expressed on the cell

Externí odkaz: https://doaj.org/article/db8e41c628a4412e85d3d2da141b5a7e

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Akademický článek

Numb Suppresses Notch-Dependent Activation of Enhancer of split during Lateral Inhibition in the Drosophila Embryonic Nervous System

Autor: Elzava Yuslimatin Mujizah, Satoshi Kuwana, Kenjiroo Matsumoto, Takuma Gushiken, Naoki Aoyama, Hiroyuki O. Ishikawa, Takeshi Sasamura, Daiki Umetsu, Mikiko Inaki, Tomoko Yamakawa, Martin Baron, Kenji Matsuno

Publikováno v: Biomolecules, Vol 14, Iss 9, p 1062 (2024)

The role of Drosophila numb in regulating Notch signaling and neurogenesis has been extensively studied, with a particular focus on its effects on the peripheral nervous system (PNS). Previous studies based on a single loss-of-function allele of numb

Externí odkaz: https://doaj.org/article/2572c86223e642aa886aeaf6fec28dac

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Akademický článek

Notch Signalling Under Maternal-to-Zygotic Transition

Autor: Tomoko Yamakawa, Elzava Yuslimatin Mujizah, Kenji Matsuno

Publikováno v: Fly, Vol 16, Iss 1, Pp 347-359 (2022)

The development of all animal embryos is initially directed by the gene products supplied by their mothers. With the progression of embryogenesis, the embryo's genome is activated to command subsequent developments. This transition, which has been st

Externí odkaz: https://doaj.org/article/3e2a5534a75d46c2a207f9b8a2cfb6b0

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Akademický článek

Notch Missense Mutations in Drosophila Reveal Functions of Specific EGF-like Repeats in Notch Folding, Trafficking, and Signaling

Autor: Hilman Nurmahdi, Mao Hasegawa, Elzava Yuslimatin Mujizah, Takeshi Sasamura, Mikiko Inaki, Shinya Yamamoto, Tomoko Yamakawa, Kenji Matsuno

Publikováno v: Biomolecules, Vol 12, Iss 12, p 1752 (2022)

Notch signaling plays various roles in cell-fate specification through direct cell–cell interactions. Notch receptors are evolutionarily conserved transmembrane proteins with multiple epidermal growth factor (EGF)-like repeats. Drosophila Notch has

Externí odkaz: https://doaj.org/article/3f5bbcf78d88431e85704ed2bedec914

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Collective nuclear behavior shapes bilateral nuclear symmetry for subsequent left-right asymmetric morphogenesis in Drosophila

Autor: Mitsutoshi Nakamura, Dongsun Shin, Mikiko Inaki, Tomoko Yamakawa, Masakazu Akiyama, Mototsugu Eiraku, Yoshitaka Morishita, Kenji Matsuno, Takeshi Sasamura

Publikováno v: Development (Cambridge, England)
article-version (VoR) Version of Record

Proper organ development often requires nuclei to move to a specific position within the cell. To determine how nuclear positioning affects left-right (LR) development in the Drosophila anterior midgut (AMG), we developed a surface-modeling method to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c948182ab373da6234c5027fb3322e28
http://europepmc.org/articles/PMC8126412

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Insight into Notch Signaling Steps That Involve pecanex from Dominant-Modifier Screens in Drosophila

Autor: Yu Atsumi, Ami Yamagishi, Kenji Matsuno, Izumi Morita, Tomoko Yamakawa, Shiori Kubo

Publikováno v: Genetics. 209:1099-1119

Notch signaling plays crucial roles in intercellular communications. In Drosophila, the pecanex (pcx) gene, which encodes an evolutionarily conserved multi-pass transmembrane protein, appears to be required to activate Notch signaling in some context

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62014549f16f46d9baa659d0fa611c78
https://doi.org/10.1534/genetics.118.300935

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Maternal almondex, a neurogenic gene, is required for proper subcellular Notch distribution in early Drosophila embryogenesis

Autor: Takeshi Sasamura, Jose L. Salazar, Kenji Matsuno, Motoo Kitagawa, Tomoko Yamakawa, Mitsutoshi Nakamura, Mikiko Inaki, Shinya Yamamoto, David Li-Kroeger, Wataru Masuda, Puspa Das

Publikováno v: Development, growthdifferentiationREFERENCES. 62(1)

Notch signaling plays crucial roles in the control of cell fate and physiology through local cell-cell interactions. The core processes of Notch signal transduction are well established, but the mechanisms that fine-tune the pathway in various develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aceaaa7ee914d34e24e6eb820c629ed
https://pubmed.ncbi.nlm.nih.gov/31782145

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