Zobrazeno 1 - 10 of 108 pro vyhledávání: '"Tomoko YAJIMA"'
1
Akademický článek
Nitroxide-Mediated Controlled Radical Copolymerization of α-Trifluoromethylstyrenes with Styrenes
Autor: Tadashi Kanbara, Yuriko Ito, Airi Yamaguchi, Tomoko Yajima
Publikováno v: Molecules, Vol 29, Iss 6, p 1214 (2024)
Fluorinated polymers are important materials in everyday life; however, most monomers of widely used fluoropolymers are gaseous, and their polymerization is difficult in an ordinary laboratory. Therefore, partially fluorinated polymers have recently
Externí odkaz: https://doaj.org/article/7312b6d4035d449bac8fc9688bef053f
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2
Akademický článek
Voltammetric Studies on the Reduction Potentials of Perfluoroalkyl Halides and Their Analogous Compounds
Autor: Airi YAMAGUCHI, Naoki SHIDA, Mahito ATOBE, Tomoko YAJIMA
Publikováno v: Electrochemistry, Vol 91, Iss 11, Pp 112016-112016 (2023)
Photocatalytic single-electron transfer (SET) reactions involving perfluoroalkyl halides play a crucial role in synthetic organic chemistry. However, the electrochemical data for these compounds, which are essential in the discussion of the SET proce
Externí odkaz: https://doaj.org/article/a2512d6827fc416d9a3dba756a74b730
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3
Akademický článek
Hydroxy- and Hydro-Perfluoroalkylation of Styrenes by Controlling the Quenching Cycle of Eosin Y
Autor: Haruko Shibata, Moeko Nakayama, Koto Tagami, Tadashi Kanbara, Tomoko Yajima
Publikováno v: Molecules, Vol 28, Iss 22, p 7577 (2023)
Fluoroalkyl compounds are widely used, underscoring a pressing need for the development of methods for their synthesis. However, reports on perfluoroalkylation to styrenes have been sparse. In this study, both hydroxy- and hydro-perfluoroalkylation o
Externí odkaz: https://doaj.org/article/aa9fdb6fd94641bd871c231bee46bb1d
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4
Akademický článek
Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ
Autor: Victoria Llado, Yuki Nakanishi, Angeles Duran, Miguel Reina-Campos, Phillip M. Shelton, Juan F. Linares, Tomoko Yajima, Alex Campos, Pedro Aza-Blanc, Michael Leitges, Maria T. Diaz-Meco, Jorge Moscat
Publikováno v: Cell Reports, Vol 10, Iss 5, Pp 740-754 (2015)
Intestinal epithelial homeostasis requires continuous renewal supported by stem cells located in the base of the crypt. Disruption of this balance results in failure to regenerate and initiates tumorigenesis. The β-catenin and Yap pathways in Lgr5+
Externí odkaz: https://doaj.org/article/61ee338e2b474571b2bcc6ac3214b30d
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5
Akademický článek
Fluorine-Containing Dibenzoanthracene and Benzoperylene-Type Polycyclic Aromatic Hydrocarbons: Synthesis, Structure, and Basic Chemical Properties
Autor: Otohiro Gotsu, Tomomi Shiota, Hiroki Fukumoto, Tomoko Kawasaki-Takasuka, Takashi Yamazaki, Tomoko Yajima, Tomohiro Agou, Toshio Kubota
Publikováno v: Molecules, Vol 23, Iss 12, p 3337 (2018)
Intramolecular photocyclization of stilbene derivatives (Mallory reaction) is one of the efficient methods for building polycyclic aromatic hydrocarbon (PAH) frameworks, and is also expected to be applicable to synthesis of fluorine-containing PAHs (
Externí odkaz: https://doaj.org/article/0f2a77733961428f9e493f47460eeff5
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6
Akademický článek
Diastereoselective radical addition to γ-alkyl-α-methylene-γ-butyrolactams and the synthesis of a chiral pyroglutamic acid derivative
Autor: Tomoko Yajima, Eriko Yoshida, Masako Hamano
Publikováno v: Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 1432-1436 (2013)
The cis- and trans-stereoselective radical additions to α-methylene-γ-alkyl- γ-lactams were investigated and the scope and limitation of the reaction were also revealed. This stereoselective radical reaction was used for synthesis of chiral pyrogl
Externí odkaz: https://doaj.org/article/cc15c26b9fd641c68ed92e2c739f553d
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10
Fine-tuning of nitrogen-containing bisphosphonate esters that potently induce degradation of HMG-CoA reductase
Autor: Kota Kawamura, Hiromasa Yoshioka, Chikako Sato, Tomoko Yajima, Yuuki Furuyama, Kouji Kuramochi, Kenji Ohgane
Publikováno v: Bioorganicmedicinal chemistry. 78
3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway, and competitive inhibitors targeting the catalytic domain of this enzyme, so-called statins, are widely used for the treatm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d5ec1723e733d3576defa28abfb158
https://pubmed.ncbi.nlm.nih.gov/36580745
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