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pro vyhledávání: '"Tomoko O. Morita"'
Autor:
Tomoko O. Morita, Kazuhiko Hanada
Publikováno v:
Cancer Chemotherapy and Pharmacology. 90:315-323
Autor:
Tomoko O, Morita, Kazuhiko, Hanada
Publikováno v:
Cancer chemotherapy and pharmacology. 90(4)
This study aimed to investigate the drug-drug interactions of ponatinib with strong, moderate, or weak CYP3A4 inhibitors/inducers by developing physiologically based pharmacokinetic (PBPK) models.SimcypThe PBPK model of ponatinib accurately represent