Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tomoko Moriyama"'
Autor:
Hiroshi Kamasaka, Yoshiaki Kagami, Tomoko Moriyama, Takashi Kuriki, Masaki Mika, Ken Omori, Zhi-Li Huang, Chikako Yokoyama, Yoshihiro Urade, Naomi Matsumoto, Koso Shiraishi, Hiroyasu Nakamura, Takashi Kometani
Publikováno v:
Sleep and Biological Rhythms. 10:38-45
We examined the effects of ornithine on the sleep-wake cycle by monitoring the electroencephalo-gram, electromyogram, and locomotor activity of freely moving mice after oral administration of it at lights-off time (18:00). Ornithine (1.0 and 3.0 g/kg
Autor:
Hitoshi Inada, Makoto Tominaga, Tomoko Moriyama, Fumitaka Fujita, Koji Shibasaki, Takaaki Sokabe, Kunitoshi Uchida, Asako Shima
Publikováno v:
Journal of Clinical Investigation. 118:4049-4057
Vertebrate cells require a very narrow pH range for survival. Cells accordingly possess sensory and defense mechanisms for situations where the pH deviates from the viable range. Although the monitoring of acidic pH by sensory neurons has been attrib
Publikováno v:
British Journal of Pharmacology. 151:134-141
Background and purpose: Parabens are commonly added in pharmaceutical, cosmetic and food products because of their wide antibacterial properties, low toxicity, inertness and chemical stability, although the molecular mechanism of their antibacterial
Autor:
Kengo Sanai, Tsukasa Sakurada, Tohru Orito, Tomoko Moriyama, Takaaki Komatsu, Shinobu Sakurada, Chikai Sakurada, Mika Sasaki
Publikováno v:
Peptides. 26:2505-2512
Injection of capsaicin into the hindpaw has been employed as a model of chemogenic nociception in mice. Intraplantar injection of nociceptin (30-240 pmol) produced a significant and dose-dependent antinociceptive activity in the capsaicin test. The n
Autor:
Kimiko Kobayashi, Makoto Tominaga, Hiroki Yamanaka, Tomoko Moriyama, Koichi Noguchi, Kazuya Togashi, Tomohiro Higashi, Yi Dai
Publikováno v:
The Journal of Neuroscience. 24:4293-4299
Proteinase-activated receptor (PAR) 2 is expressed on a subset of primary afferent neurons and involved in inflammatory nociception. Transient receptor potential vanilloid subfamily 1 (TRPV1) is a sensory neuron-specific cation channel that responds
Autor:
Tatsuo Watanabe, Tohru Fushiki, Makoto Tominaga, Akihito Morita, S. Hashizume, Namie Murayama, Susumu Yazawa, Kenji Kobata, Tohko Iida, Tomoko Moriyama
Publikováno v:
Neuropharmacology. 44:958-967
Capsiate is a capsaicin-like ingredient of a non-pungent cultivar of red pepper, CH-19 sweet. To elucidate the mechanisms underlying the non-pungency of capsiate, we investigated whether capsiate activates the cloned capsaicin receptor, TRPV1 (VR1).
Autor:
Tomoko Moriyama, Shinya Ueno, Takeshi Katsuragi, Tsukasa Sakurada, Kenji Honda, Hiro-o Kamiya
Publikováno v:
Drug Development Research. 59:104-111
In the present study, we examined the involvement of P2X receptors in neuropathic pain using the chronic constriction injury (CCI) model. The thermal and mechanical nociceptive thresholds were evaluated using the paw withdrawal test and a von Frey te
Autor:
Takeshi Katsuragi, Yukio Takano, Shinya Ueno, Kenji Honda, Hiromi Yamada, Tomoko Moriyama, Hiro-o Kamiya
Publikováno v:
Brain Research Protocols. 10:95-101
The P2X receptor is a receptor-gated cationic channel that responds to ATP. The quantification of P2X mRNA expression in dorsal root ganglion (DRG) provides important information for neuropathic pain studies. We developed a rapid and sensitive extern
Publikováno v:
Neuroscience Letters. 322:161-164
We examined the role of the spinal muscarinic receptor subtype in the anti-nociceptive effect of intrathecal (i.t.) α 2 adrenoceptor agonist clonidine in mice. I.t. injection of the muscarinic receptor antagonist atropine completely inhibited i.t. c
Publikováno v:
Ergonomics. 42:964-979
The present paper aimed at determining the combined effects of two different levels of air permeability and moisture absorption, in terms of clothing microclimate and subjective sensation, in resting and exercising subjects at an ambient temperature