Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tomoko Minegishi"'
Autor:
Yuka Igarashi, Toru Uchiyama, Tomoko Minegishi, Sirirat Takahashi, Nobuyuki Watanabe, Toshinao Kawai, Masafumi Yamada, Tadashi Ariga, Masafumi Onodera
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 6, Iss C, Pp 8-16 (2017)
Clinical improvement in stem cell gene therapy (SCGT) for primary immunodeficiencies depends on the engraftment levels of genetically corrected cells, and tracing the transgene in each hematopoietic lineage is therefore extremely important in evaluat
Externí odkaz:
https://doaj.org/article/ed70ec7c4d1c4466aa7a2d0b95a82b56
Autor:
Takuya Shuo, Naohiko Koshikawa, Daisuke Hoshino, Tomoko Minegishi, Hiroko Ao-Kondo, Masaaki Oyama, Sadanori Sekiya, Shinichi Iwamoto, Koichi Tanaka, Motoharu Seiki
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43751 (2012)
BACKGROUND: Glycosylation is an important and universal post-translational modification for many proteins, and regulates protein functions. However, simple and rapid methods to analyze glycans on individual proteins have not been available until rece
Externí odkaz:
https://doaj.org/article/6399f8a4bab04b4c9d83a710c233f56b
Autor:
Motoharu Seiki, Alissa M. Weaver, Kazuki Nabeshima, Shingo Miyamoto, Takashi Nakagawa, Takayuki Sueta, Mikiko Aoki, Sung-Ouk Nam, Taizo Tomari, Tomoko Minegishi, Hiroaki Taniguchi, Daisuke Hoshino, Naohiko Koshikawa
Supplementary Figure S3. Cleavage of EphA2 in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0045606bf5bc8183a7e00d40707e5cfd
https://doi.org/10.1158/0008-5472.22404824.v1
https://doi.org/10.1158/0008-5472.22404824.v1
Autor:
Motoharu Seiki, Alissa M. Weaver, Kazuki Nabeshima, Shingo Miyamoto, Takashi Nakagawa, Takayuki Sueta, Mikiko Aoki, Sung-Ouk Nam, Taizo Tomari, Tomoko Minegishi, Hiroaki Taniguchi, Daisuke Hoshino, Naohiko Koshikawa
Supplementary Methods, Figure Legends and References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5435b4d13ac458cb3462ab02d8f3856b
https://doi.org/10.1158/0008-5472.22404803
https://doi.org/10.1158/0008-5472.22404803
Autor:
Motoharu Seiki, Eisuke Mekada, Ryo Iwamoto, Tomoko Minegishi, Hiroto Mizushima, Naohiko Koshikawa
Epidermal growth factor (EGF) receptors (ErbB) and EGF family members represent promising targets for cancer therapy. Heparin-binding EGF (HB-EGF) is a member of the EGF family and is an important target for therapy in some types of human cancers. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::531ec3c48f9b32bf7824f6727b962240
https://doi.org/10.1158/0008-5472.c.6500552
https://doi.org/10.1158/0008-5472.c.6500552
Autor:
Motoharu Seiki, Eisuke Mekada, Ryo Iwamoto, Tomoko Minegishi, Hiroto Mizushima, Naohiko Koshikawa
Supplementary Methods, Table 1, Figures 1-8 from Membrane Type 1-Matrix Metalloproteinase Cleaves Off the NH2-Terminal Portion of Heparin-Binding Epidermal Growth Factor and Converts It into a Heparin-Independent Growth Factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a71ff7f3f56d20718fdfdbf3a78b30
https://doi.org/10.1158/0008-5472.22383470
https://doi.org/10.1158/0008-5472.22383470
Autor:
Shingo Miyamoto, Tomoko Minegishi, Fusanori Yotsumoto, Naohiko Koshikawa, Fuyuki Eguchi, Motoharu Seiki, Hiroto Mizushima, Kazuki Nabeshima, Eisuke Mekada
Publikováno v:
Cancer Science. 102:111-116
Increased expression of heparin-binding EGF-like growth factor (HB-EGF) and membrane-type matrix metalloproteinase-1 (MT1-MMP) is frequently associated with various types of malignant tumor. HB EGF-like growth factor has been reported to promote the
Publikováno v:
Cancer Research. 68:530-536
Laminin-5 (Ln-5), a heterotrimer composed of three different laminin chains [laminin-α3 (Ln-α3), laminin-β3 (Ln-β3), and laminin-γ2 (Ln-γ2)], is a major component of the basement membrane in most adult tissues. One of the chains, Ln-γ2, is a s
Autor:
Naohiko Koshikawa, Tomoko Minegishi, Takashi Karashima, Taro Shuin, Chiaki Kawada, Motoharu Seiki, Masayuki Kamada
Publikováno v:
Cancer Science
Lack of appropriate biomarkers has hampered early detection of urothelial cancer (UC), therefore, development of biomarkers for its diagnosis at earlier stages is of importance. Laminin-332 (Ln-332, formerly Ln-5), a component of basement membranes,
Membrane-type Matrix Metalloproteinase-1 (MT1-MMP) Is a Processing Enzyme for Human Laminin γ2 Chain
Publikováno v:
Journal of Biological Chemistry. 280:88-93
Processing of the laminin-5 (Ln-5) gamma 2 chain by membrane-type-1 matrix metalloproteinases (MT1-MMP) promotes migration and invasion of epithelial and tumor cells. We previously demonstrated that MT1-MMP cleaves the rat gamma 2 chain at two sites,