Výsledky vyhledávání - "Tomoko Kanno"

Inhibitory Effect of Gnetin C, a Resveratrol Dimer from Melinjo (Gnetum gnemon), on Tyrosinase Activity and Melanin Biosynthesis

Autor: Ken Hashimoto, Miyako Yanagihara, Akinori Inoue, Tomoko Kanno, Tomoki Tatefuji, Maiko Yoshimatsu

Publikováno v: Biological and Pharmaceutical Bulletin. 35:993-996

Tyrosinase is the key enzyme involved in melanogenesis. The aim of this study was to investigate the in vitro inhibitory effects of gnetin C, a resveratrol dimer isolated from melinjo (Gnetum gnemon) seeds, on tyrosinase activity and melanin biosynth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87adadefba464f5e77b0a6f1f2bdc21d
https://doi.org/10.1248/bpb.35.993

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Molecular mechanism of diclofenac-induced apoptosis of promyelocytic leukemia: dependency on reactive oxygen species, akt, bid, cytochrome and caspase pathway

Autor: Hiroshi Tamai, Akiko Inoue, Tomoko Kanno, Kozo Utsumi, Hirofumi Fujita, Shikibu Muranaka

Publikováno v: Free Radical Biology and Medicine. 37:1290-1299

Nonsteroidal anti-inflammatory drugs (NSAIDs) induce apoptosis in a variety of cells, but the mechanism of this effect has not been fully elucidated. We report that diclofenac, a NSAID, induces growth inhibition and apoptosis of HL-60 cells through m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c011bfd06beee490ac962afc0b31de7
https://doi.org/10.1016/j.freeradbiomed.2004.07.003

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Involvement of Ceramide in the Mechanism of Cr(VI)-induced Apoptosis of CHO Cells

Autor: Tatsuji Yasuda, Hirofumi Fujita, Tomoko Kanno, Hirotsugu Kobuchi, Shikibu Muranaka, Kozo Utsumi, Jitsuo Akiyama

Publikováno v: Free Radical Research. 38:613-621

Mitochondria reduce Cr(VI) to Cr(V) with concomitant generation of reactive oxygen species, thereby exhibiting cytotoxic effects leading to apoptosis in various types of cells. To clarify the mechanism by which Cr(VI) induces apoptosis, we examined t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d168717760303817c041ed1fb7866a
https://doi.org/10.1080/10715760410001694035

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Role of α-Tocopherol in the Regulation of Mitochondrial Membrane Permeability Transition

Autor: Eisuke F. Sato, Tomoko Kanno, Masae Yorimitsu, Makoto Nagano, Akiko Inoue, Kozo Utsumi, Shikibu Muranaka, Masayasu Inoue

Publikováno v: Journal of Clinical Biochemistry and Nutrition. 35:7-15

Although information about the mechanism of apoptosis is rapidly increasing, critical roles of mitochondria in the regulation of cell death remain to be elucidated. Recent studies revealed that reactive oxygen species (ROS) in cells increase prior to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf88dde1ac322621c48af8a4697461ff
https://doi.org/10.3164/jcbn.35.7

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Cyclosporin A inhibits thyroid hormone-induced shortening of the tadpole tail through membrane permeability transition

Autor: Akihiko Kashiwagi, Eisuke F. Sato, Kozo Utsumi, Tomoko Kanno, Kenjiro Katsu, Junzo Sasaki, Hideki Hanada, Masayasu Inoue

Publikováno v: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 135:473-483

Regression of the tadpole tail through muscule cell apoptosis is one of the most spectacular events in amphibian metamorphosis. Accumulated evidence has shown that mitochondrial membrane permeability transition (MPT) plays a crucial role in apoptosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe064435a9065dcb9e8b0be2a1f35575
https://doi.org/10.1016/s1096-4959(03)00113-1

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The effects of immunosuppressants on FAS-mediated activation-induced cell death in human T lymphocytes

Autor: Takuzo, Fujiwara, Yoshihiro, Ikeda, Kayo, Arita, Tomoko, Kanno, Yoshiki, Takehara, Munehisa, Yabuki, Kozo, Utsumi

Publikováno v: Transplant International. 16:108-114

The effects of cyclosporin A (CsA) and methylprednisolone (MP) on Fas-mediated activation-induced cell death (FMAICD) of T lymphocytes were examined. T lymphocytes were activated with the immobilized anti-CD 3 and CD 28 monoclonal antibodies (MoAbs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0457e17893b9154ed1694db83a234009
https://doi.org/10.1111/j.1432-2277.2003.tb00271.x

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Activation of Caspase-3 by Lysosomal Cysteine Proteases and Its Role in 2,2'-Azobis-(2-Amidinopropane)Dihydrochloride (AAPH)--Induced Apoptosis in HL-60 Cells

Autor: Tamotsu Yoshioka, Rumi Ishisaka, Toshihiko Utsumi, Tomoko Kanno, Kozo Utsumi, Jitsuo Akiyama

Publikováno v: Journal of Biochemistry. 129:35-41

We previously reported that in addition to mitochondrial cytochrome c dependent activation, lysosomal cysteine proteases were also involved in the activation of caspase-3. In this study, we have separately obtained the lysosomal and mitochondrial cas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b859c94a0a61aa26173be780c4efe40
https://doi.org/10.1093/oxfordjournals.jbchem.a002833

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Mechanism of α-tocopheryl succinate-induced apoptosis of promyelocytic leukemia cells

Autor: Rumi Ishisaka, Hirotsugu Kobuchi, Kayo Arita, Tomoko Kanno, Kozo Utsumi, Hiroshi Tamai, Shinji Yamamoto

Publikováno v: Free Radical Research. 33:407-418

Selective induction of apoptosis in tumor cells is important for treating patients with cancer. Because oxidative stress plays an important role in the process of apoptosis, we studied the effect of alpha-tocopheryl succinate (VES) on the fate of cul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511eb317645559309afafc99c2e5e40a
https://doi.org/10.1080/10715760000300941

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